N,N-dipropylnitrous amide

C6H14N2O

CAS621-64-7
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Danger

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Identification

CAS Number
621-64-7
EC Number
210-698-0
UN Number
3082
Index Number
612-098-00-8
PubChem CID
12130

Physical-chemical properties

Molecular Formula
C6H14N2O
Molar Mass
130.19 g/mol
IUPAC Name
N,N-dipropylnitrous amide

Chemical Identifiers

InChI
InChI=1S/C6H14N2O/c1-3-5-8(7-9)6-4-2/h3-6H2,1-2H3
InChI Key
YLKFDHTUAUWZPQ-UHFFFAOYSA-N

Overview

N,N-dipropylnitrous amide (CAS 621-64-7) is a nitrosoamine compound with significant carcinogenic properties and specialized industrial applications. This organic chemical compound, also identified by EC number 210-698-0, belongs to the nitrosoamine family and exhibits a molecular formula of C6H14N2O with a molecular weight of 130.19 g/mol. N,N-dipropylnitrous amide is classified under ADR Class 9 miscellaneous dangerous substances, reflecting its complex hazard profile that requires careful handling and storage protocols. The compound presents serious health concerns, classified as Carcinogenic Category 1B under the GHS system, indicating sufficient evidence of carcinogenic potential in humans. Additional hazard classifications include Acute Toxicity Category 4 and Aquatic Chronic Toxicity Category 2, necessitating appropriate safety measures during handling and disposal. The associated GHS pictograms (GHS08, GHS07, GHS09) and "Danger" signal word emphasize the critical importance of following established safety protocols. Safety considerations are paramount when working with this substance, requiring proper personal protective equipment, adequate ventilation systems, and trained personnel familiar with nitrosoamine handling procedures. Unlike structurally different compounds such as 4-(4-amino-3-methylphenyl)-2-methylaniline, which belongs to the aminobiphenyl family, N,N-dipropylnitrous amide requires specialized containment measures due to its distinct chemical behavior and toxicological profile. Primary industrial applications include use as a chemical intermediate in pharmaceutical synthesis, specialized research applications in analytical chemistry, and as a reagent in controlled chemical processes where its unique nitrosoamine properties are specifically required. OYSI maintains availability of N,N-dipropylnitrous amide for qualified industrial customers with appropriate handling capabilities and regulatory compliance frameworks.

Safety & Classification

Danger
Classification:

Carc. 1B; Acute Tox. 4 *; Aquatic Chronic 2

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H350

May cause cancer.

H302

Harmful if swallowed.

H411

Toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number3082
ADR Class9
Packing GroupIII
Tunnel Code-
Proper Shipping NameNitrosodipropylamin
Marine PollutantNo

Frequently Asked Questions

What is N,N-dipropylnitrous amide?

N,N-dipropylnitrous amide is an organic chemical compound with the molecular formula C6H14N2O and CAS number 621-64-7. This nitrous amide derivative has a molecular weight of 130.19 g/mol and belongs to the family of N-nitrosamines. It is classified as a Category 1B carcinogen under CLP regulation, indicating strong evidence of carcinogenic potential in humans. The compound also presents acute toxicity and chronic aquatic toxicity hazards, requiring careful handling and regulatory compliance in industrial applications.

What are the physicochemical properties of N,N-dipropylnitrous amide?

N,N-dipropylnitrous amide typically exists as a liquid at room temperature due to its organic structure with two propyl groups attached to the nitrous amide moiety. The compound's molecular weight of 130.19 g/mol suggests moderate volatility. As a nitrous amide, it likely exhibits limited water solubility but good solubility in organic solvents. The presence of the N-N=O functional group contributes to its chemical reactivity and stability characteristics, though specific physical properties like boiling point and density require laboratory analysis for precise determination.

What is N,N-dipropylnitrous amide used for?

N,N-dipropylnitrous amide serves primarily as a chemical intermediate in specialized organic synthesis and research applications. Due to its carcinogenic classification (Carc. 1B), its use is heavily restricted and typically limited to controlled laboratory environments for analytical purposes or specific chemical research. Industrial applications are minimal due to safety concerns and regulatory restrictions. The compound may be used in trace amounts for analytical reference standards or in highly controlled research settings studying nitrosamine chemistry, always requiring strict safety protocols and regulatory compliance.

How to handle N,N-dipropylnitrous amide safely?

N,N-dipropylnitrous amide requires maximum safety precautions due to its Category 1B carcinogenic classification and acute toxicity. Essential PPE includes chemical-resistant gloves, safety goggles, and respiratory protection to prevent inhalation exposure. Work must be conducted in well-ventilated areas or fume hoods to minimize vapor exposure. Avoid skin contact, ingestion, and inhalation at all costs. Use only the minimum quantities necessary and ensure all personnel are trained in carcinogen handling procedures. Emergency eyewash and shower facilities must be readily accessible during handling operations.

How to store N,N-dipropylnitrous amide correctly?

N,N-dipropylnitrous amide must be stored in a cool, dry, well-ventilated area away from direct sunlight and heat sources to prevent decomposition. Use tightly sealed, chemically compatible containers to prevent vapor release and contamination. Storage areas should be designated for carcinogenic materials with restricted access and appropriate warning signage. Maintain temperatures below 25°C when possible and ensure separation from incompatible materials such as strong oxidizers. Regular container inspection is essential to detect any leaks or deterioration that could lead to exposure risks.

What to do in case of contact with N,N-dipropylnitrous amide?

Immediate action is critical upon contact with N,N-dipropylnitrous amide due to its carcinogenic and toxic properties. For skin contact, remove contaminated clothing and flush the affected area with copious amounts of water for at least 15 minutes. If inhaled, move the person to fresh air immediately and seek medical attention. For eye contact, rinse thoroughly with water for at least 15 minutes while holding eyelids open. In all cases, seek immediate medical attention and inform healthcare providers of the specific chemical involved and its hazardous properties.

How to dispose of N,N-dipropylnitrous amide properly?

N,N-dipropylnitrous amide disposal requires specialized hazardous waste management due to its carcinogenic classification and environmental impact. The compound must never be disposed of in regular waste streams or poured down drains. Contact licensed hazardous waste disposal companies experienced in handling carcinogenic materials. Waste must be properly labeled, documented, and transported according to ADR Class 9 requirements. Incineration at high temperatures in specialized facilities is typically the preferred disposal method. Maintain detailed waste tracking documentation and ensure compliance with local and European waste regulations including the Basel Convention.

How to transport N,N-dipropylnitrous amide?

N,N-dipropylnitrous amide is classified under ADR Class 9 (Miscellaneous dangerous goods), Packing Group III for transportation purposes. This classification requires proper packaging in UN specification containers with appropriate marking and labeling including GHS pictograms GHS07, GHS08, and GHS09. Transport documents must include proper shipping names, UN numbers, and hazard declarations. Vehicles must carry appropriate emergency equipment and drivers require ADR training. Due to its carcinogenic properties, additional precautions may be required including route planning to avoid populated areas and ensuring emergency response capabilities along transport routes.

Is N,N-dipropylnitrous amide subject to particular regulations?

N,N-dipropylnitrous amide is subject to extensive European chemical regulations including REACH registration requirements and CLP classification obligations. Its Category 1B carcinogenic classification triggers strict workplace exposure limits and mandatory risk assessment procedures under occupational health directives. The compound requires safety data sheets compliant with REACH Annex II and may be subject to authorization or restriction procedures. Environmental regulations apply due to its Aquatic Chronic 2 classification. Import/export may require permits, and industrial use typically requires notification to relevant authorities and implementation of comprehensive risk management measures.

Where to buy N,N-dipropylnitrous amide in Europe?

OYSI serves as a specialized European distributor for N,N-dipropylnitrous amide, providing regulatory-compliant supply to qualified industrial and research customers. Due to the compound's carcinogenic classification and regulatory restrictions, purchase requires proper business justification and compliance with local handling regulations. OYSI ensures proper documentation, safety data sheets, and regulatory guidance for European customers. Orders typically require advance qualification of end-use applications and confirmation of appropriate safety measures. Contact OYSI directly to discuss availability, regulatory requirements, and technical support for your specific application needs.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.