N,N-dipropylnitrous amide

C6H14N2O

CAS621-64-7
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Danger

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Identification

CAS Number
621-64-7
EC Number
210-698-0
UN Number
3082
Index Number
612-098-00-8
PubChem CID
12130

Physical-chemical properties

Molecular Formula
C6H14N2O
Molar Mass
130.19 g/mol
IUPAC Name
N,N-dipropylnitrous amide

Chemical Identifiers

InChI
InChI=1S/C6H14N2O/c1-3-5-8(7-9)6-4-2/h3-6H2,1-2H3
InChI Key
YLKFDHTUAUWZPQ-UHFFFAOYSA-N

Overview

N,N-dipropylnitrous amide (CAS 621-64-7) is an organic nitrosamine compound with significant carcinogenic properties and industrial research applications. This chemical substance, also identified by EC number 210-698-0, belongs to the nitrosamine family of compounds characterized by the presence of the nitroso functional group (-N=O) attached to an amine structure. With a molecular formula of C6H14N2O and molecular weight of 130.19 g/mol, N,N-dipropylnitrous amide represents a specific example of dialkylnitrosamines that have garnered considerable attention in both industrial and regulatory contexts due to their toxicological profiles. The compound exhibits significant safety concerns, classified under GHS as Carcinogenic Category 1B, indicating strong evidence of carcinogenic potential in humans. Additional hazard classifications include Acute Toxicity Category 4 and Aquatic Chronic Toxicity Category 2, requiring careful handling protocols and environmental considerations. The associated GHS pictograms GHS08, GHS07, and GHS09 reflect its health hazards and environmental impact potential. Transportation falls under ADR Class 9 (miscellaneous dangerous goods), emphasizing the need for specialized logistics handling. In industrial applications, N,N-dipropylnitrous amide finds use primarily in analytical chemistry as a reference standard for nitrosamine detection and quantification methods. It serves as a research chemical in toxicological studies and pharmaceutical impurity testing protocols. The compound is also utilized in environmental monitoring applications, particularly in studies examining nitrosamine contamination pathways, alongside related compounds such as 4-(4-amino-3-methylphenyl)-2-methylaniline which appears in similar analytical contexts. OYSI maintains technical-grade N,N-dipropylnitrous amide availability for qualified industrial and research customers, ensuring compliance with European chemical safety regulations and proper documentation for controlled substance handling.

Safety & Classification

Danger
Classification:

Carc. 1B; Acute Tox. 4 *; Aquatic Chronic 2

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H350

May cause cancer.

H302

Harmful if swallowed.

H411

Toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number3082
ADR Class9
Packing GroupIII
Tunnel Code-
Proper Shipping NameNitrosodipropylamin
Marine PollutantNo

Frequently Asked Questions

What is N,N-dipropylnitrous amide?

N,N-dipropylnitrous amide is a chemical compound with the molecular formula C6H14N2O and CAS number 621-64-7. This substance belongs to the nitrous amide family and has a molecular weight of 130.19 g/mol. It is classified as a Category 1B carcinogen and presents significant health hazards, requiring careful handling and strict safety protocols in professional environments.

What are the physicochemical properties of N,N-dipropylnitrous amide?

N,N-dipropylnitrous amide is an organic compound with the molecular formula C6H14N2O and a molecular weight of 130.19 g/mol. As a nitrous amide derivative, it typically exists as a liquid or solid at room temperature. The compound contains nitrogen-oxygen and carbon-nitrogen bonds characteristic of nitrous amides, which influence its chemical reactivity and stability properties.

What is N,N-dipropylnitrous amide used for?

N,N-dipropylnitrous amide is primarily used in specialized chemical research and industrial applications. Due to its carcinogenic classification (Category 1B), its use is restricted to controlled professional environments with appropriate safety measures. Applications may include chemical synthesis processes, research activities, and specific industrial processes where its unique chemical properties are required under strict regulatory compliance.

How to handle N,N-dipropylnitrous amide safely?

N,N-dipropylnitrous amide requires extreme caution due to its carcinogenic properties (Category 1B) and acute toxicity. Personal protective equipment must include chemical-resistant gloves, protective clothing, eye protection, and respiratory protection. Work should be conducted in well-ventilated areas or under fume hoods. Avoid skin contact, inhalation, and ingestion. Emergency procedures and decontamination protocols must be established before handling.

How to store N,N-dipropylnitrous amide correctly?

N,N-dipropylnitrous amide should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Due to its carcinogenic classification, storage areas must be restricted to authorized personnel only. Containers should be properly labeled with hazard warnings and stored according to local regulations for Category 1B carcinogens.

What to do in case of contact with N,N-dipropylnitrous amide?

Immediate action is required in case of contact with N,N-dipropylnitrous amide due to its toxicity. For skin contact, remove contaminated clothing and wash thoroughly with soap and water. In case of eye contact, flush immediately with water for at least 15 minutes. If inhaled, move to fresh air immediately. Seek medical attention in all cases of exposure and inform medical personnel of the carcinogenic nature of the substance.

How to dispose of N,N-dipropylnitrous amide appropriately?

N,N-dipropylnitrous amide must be disposed of as hazardous waste due to its carcinogenic properties and environmental classification (Aquatic Chronic 2). Disposal must comply with local, national, and EU regulations for hazardous chemical waste. Contact licensed waste disposal companies specialized in handling carcinogenic substances. Never discharge to sewers, soil, or water bodies. Maintain disposal records as required by regulations.

How to transport N,N-dipropylnitrous amide?

N,N-dipropylnitrous amide is classified under ADR Class 9 (Miscellaneous dangerous substances), Packing Group III for transport purposes. It requires appropriate UN-specification packaging with proper hazard labels and documentation. Transport must comply with ADR/RID regulations for Class 9 substances. Vehicles must carry appropriate emergency equipment and drivers must have proper training for hazardous materials transport.

Is N,N-dipropylnitrous amide subject to specific regulations?

N,N-dipropylnitrous amide is subject to strict regulations under REACH and CLP due to its carcinogenic classification (Category 1B). It requires safety data sheets, proper classification and labeling with GHS pictograms (GHS08, GHS07, GHS09), and the signal word 'Danger'. Users must comply with occupational exposure limits, authorization procedures, and workplace safety regulations for carcinogenic substances.

Where to buy N,N-dipropylnitrous amide in Europe?

N,N-dipropylnitrous amide is available through specialized chemical distributors like OYSI, a European distributor of technical chemicals. Due to its carcinogenic classification, purchase is restricted to qualified professionals and companies with appropriate handling capabilities and regulatory compliance. Buyers must provide proper documentation and meet regulatory requirements for handling Category 1B carcinogenic substances before purchase approval.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.