4-chloro-3,5-dimethylphenol

4-chloro-3,5-dimethylphenol is an organic chemical compound with the molecular formula C8H9ClO and CAS number 88-04-0. This chlorinated phenolic compound has a molecular weight of 156.61 g/mol and belongs to the family of substituted phenols. It features a benzene ring substituted with two methyl groups at positions 3 and 5, a chlorine atom at position 4, and a hydroxyl group, giving it both aromatic and phenolic properties essential for various industrial applications.

4-chloro-3,5-dimethylphenol typically appears as a white to off-white crystalline solid at room temperature. The compound has a characteristic phenolic odor and exhibits moderate solubility in organic solvents such as alcohols and ethers, while showing limited solubility in water due to its hydrophobic chlorinated aromatic structure. Its phenolic hydroxyl group allows for hydrogen bonding, influencing its melting point and solubility characteristics in polar solvents.

4-chloro-3,5-dimethylphenol serves primarily as an important intermediate in the synthesis of antimicrobial agents, preservatives, and disinfectants. It is commonly used in the pharmaceutical industry for manufacturing antiseptic compounds and in the production of specialized biocides. The compound also finds applications in the synthesis of other chlorinated phenolic derivatives used in industrial processes, where its antimicrobial properties and chemical stability make it valuable for various formulation purposes.

4-chloro-3,5-dimethylphenol requires careful handling due to its classification as Acute Tox. 4, Skin Irrit. 2, Eye Irrit. 2, and Skin Sens. 1. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and protective clothing to prevent skin and eye contact. Work should be conducted in well-ventilated areas or under fume hoods to minimize inhalation exposure. Always wash hands thoroughly after handling and avoid eating, drinking, or smoking in work areas.

4-chloro-3,5-dimethylphenol should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Keep containers away from incompatible materials such as strong oxidizers and bases that could react with the phenolic compound. Storage areas should be equipped with appropriate containment measures to prevent environmental release. Maintain temperatures below 25°C when possible and ensure containers are properly labeled according to GHS requirements.

Immediate action is required for any contact with 4-chloro-3,5-dimethylphenol due to its irritant and sensitizing properties. For skin contact, remove contaminated clothing and rinse affected area with plenty of water for at least 15 minutes. In case of eye contact, flush eyes with clean water for at least 15 minutes while holding eyelids open. If inhaled, move to fresh air immediately. Seek medical attention for persistent irritation or if large amounts were involved in exposure.

4-chloro-3,5-dimethylphenol must be disposed of as hazardous waste according to local, national, and European waste regulations. The compound cannot be disposed of in regular waste streams due to its toxic properties and environmental impact potential. Arrange disposal through licensed hazardous waste contractors who can handle chlorinated organic compounds appropriately. Incineration at high temperatures in specialized facilities is typically the preferred disposal method, ensuring complete destruction while preventing environmental contamination.

4-chloro-3,5-dimethylphenol is classified under ADR as Class 6.1 (toxic substances), Packing Group II, indicating moderate toxicity requiring specific transport precautions. Packages must be properly labeled with appropriate hazard labels and shipping names according to dangerous goods regulations. Transport vehicles must carry appropriate emergency equipment and documentation. Only authorized carriers experienced in handling toxic chemicals should transport this substance, ensuring compliance with international dangerous goods transport regulations throughout the supply chain.

4-chloro-3,5-dimethylphenol is subject to European REACH regulation requiring registration for commercial use and CLP regulation for classification and labeling as indicated by its GHS07 pictogram and warning signal word. The compound is not currently listed as a Substance of Very High Concern (SVHC). Users must comply with occupational exposure limits, proper hazard communication, and safety data sheet requirements. National regulations may impose additional restrictions on use, handling, and disposal of this toxic substance.

4-chloro-3,5-dimethylphenol is available through OYSI, a leading European distributor of specialized chemical products. OYSI provides this compound to industrial customers across Europe, ensuring compliance with all relevant European chemical regulations including REACH and CLP requirements. As an established chemical distributor, OYSI offers reliable supply chains, proper documentation, and technical support for customers requiring this chlorinated phenolic compound for their industrial applications and synthesis processes.