3,5-dimethylphenol

C8H10O

CAS108-68-9
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
GHS05 Gefahrensymbol: Ätzend – Ätzwirkung
Danger

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Identification

CAS Number
108-68-9
EC Number
203-606-5
UN Number
2261
Index Number
604-037-00-9
PubChem CID
7948

Physical-chemical properties

Molecular Formula
C8H10O
Molar Mass
122.16 g/mol
IUPAC Name
3,5-dimethylphenol

Chemical Identifiers

InChI
InChI=1S/C8H10O/c1-6-3-7(2)5-8(9)4-6/h3-5,9H,1-2H3
InChI Key
TUAMRELNJMMDMT-UHFFFAOYSA-N

Overview

3,5-dimethylphenol (CAS 108-68-9) is an aromatic organic compound characterized by two methyl groups positioned on a phenolic ring structure. This dimethylphenol derivative represents an important intermediate in organic synthesis and industrial chemistry applications. The compound features a benzene ring with a hydroxyl group and two methyl substituents at the 3 and 5 positions, giving it distinct chemical properties compared to other phenolic compounds. With a molecular formula of C8H10O and molecular weight of 122.16 g/mol, 3,5-dimethylphenol exhibits typical phenolic reactivity while the methyl groups influence its solubility and reaction characteristics. The substance is classified under multiple acute toxicity categories and as a skin corrosive material (Class 1B), requiring careful handling protocols and appropriate personal protective equipment. Its hazard classification includes GHS pictograms for toxicity (GHS06) and corrosion (GHS05), with "Danger" as the signal word. Transportation falls under ADR Class 6.1, reflecting its toxic properties during shipping and storage. In industrial applications, 3,5-dimethylphenol serves as a chemical intermediate in pharmaceutical synthesis, polymer production, and specialty chemical manufacturing. It finds use in the production of antioxidants, disinfectants, and various organic compounds where its specific substitution pattern provides desired molecular properties. The compound shares applications with related phenolic substances like 4-methylphenol, though its unique positioning of methyl groups offers distinct advantages in certain synthetic pathways. OYSI maintains reliable supply chains for 3,5-dimethylphenol, ensuring consistent availability for European industrial customers requiring this specialized aromatic intermediate for their manufacturing processes.

Safety & Classification

Danger
Classification:

Acute Tox. 3 *; Acute Tox. 3 *; Skin Corr. 1B

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H311

Toxic in contact with skin.

H301

Toxic if swallowed.

H314

Causes severe skin burns and eye damage.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Skin Contact

Toxic

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Harmful

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Toxic

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2261
ADR Class6.1
Packing GroupII
Tunnel CodeD/E
Proper Shipping Name3,5-Xylenol, fest
Marine PollutantNo

Frequently Asked Questions

What is 3,5-dimethylphenol?

3,5-dimethylphenol is an organic compound with the molecular formula C8H10O and CAS number 108-68-9. It belongs to the phenol family and features two methyl groups attached to the benzene ring at positions 3 and 5. With a molecular weight of 122.16 g/mol, this aromatic compound is classified as a hazardous substance with acute toxicity and skin corrosion properties, requiring careful handling in industrial applications.

What are the physicochemical properties of 3,5-dimethylphenol?

3,5-dimethylphenol is typically a white to pale yellow crystalline solid at room temperature with a characteristic phenolic odor. As a phenolic compound, it exhibits moderate solubility in water and good solubility in organic solvents such as alcohols and ethers. The compound has a melting point around 63-65°C and demonstrates typical aromatic stability while maintaining the reactive hydroxyl group characteristic of phenols.

What is 3,5-dimethylphenol used for?

3,5-dimethylphenol is primarily used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and specialty chemicals. It serves as a building block for manufacturing antioxidants, preservatives, and various organic compounds. The compound is also utilized in the production of resins, polymers, and as a chemical intermediate in the synthesis of more complex aromatic compounds for industrial applications.

How to handle 3,5-dimethylphenol safely?

3,5-dimethylphenol requires strict safety measures due to its Acute Tox. 3 and Skin Corr. 1B classifications. Essential protective equipment includes chemical-resistant gloves, safety goggles, and protective clothing to prevent skin contact. Work should be conducted in well-ventilated areas or under fume extraction systems. The GHS06 and GHS05 pictograms indicate both acute toxicity and corrosive hazards, requiring immediate medical attention if exposure occurs.

How to store 3,5-dimethylphenol correctly?

3,5-dimethylphenol should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Storage areas must be equipped with appropriate containment measures and maintained at stable temperatures. The compound should be kept away from incompatible materials such as strong oxidizing agents and bases. Regular container inspection is essential to prevent leakage and ensure integrity.

What to do in case of contact with 3,5-dimethylphenol?

Immediate action is required due to the compound's corrosive properties. For skin contact, remove contaminated clothing and flush affected areas with plenty of water for at least 15 minutes, then seek medical attention immediately. In case of eye contact, rinse thoroughly with water for at least 15 minutes and obtain emergency medical care. If inhaled, move the person to fresh air and seek medical attention if breathing difficulties occur.

How to dispose of 3,5-dimethylphenol appropriately?

3,5-dimethylphenol disposal must comply with local and national hazardous waste regulations due to its toxic and corrosive properties. The compound should never be poured down drains or disposed of with regular waste. Professional hazardous waste disposal services should handle collection and treatment, typically through high-temperature incineration at authorized facilities. Proper documentation and waste classification codes must accompany all disposal activities.

How to transport 3,5-dimethylphenol?

3,5-dimethylphenol is classified as ADR Class 6.1 (toxic substances), Packaging Group II, requiring specific transport regulations compliance. Packages must be properly labeled with appropriate hazard markings and UN identification numbers. Transport vehicles need proper documentation including safety data sheets and emergency response information. Only certified carriers experienced in hazardous materials transport should handle shipments, ensuring proper containment and emergency preparedness throughout transit.

Is 3,5-dimethylphenol subject to specific regulations?

3,5-dimethylphenol is subject to REACH regulation for registration and authorization within the EU market. The compound falls under CLP regulation requiring proper classification, labeling, and packaging with GHS06 and GHS05 pictograms. While not currently listed as an SVHC substance, it remains subject to standard chemical safety assessments and may face additional restrictions depending on specific applications and exposure scenarios in different EU member states.

Where to buy 3,5-dimethylphenol in Europe?

3,5-dimethylphenol is available through OYSI, a specialized European distributor of technical chemicals serving industrial customers across the region. As a professional chemical supplier, OYSI ensures full regulatory compliance, proper documentation, and safe packaging for hazardous materials transport. Contact OYSI directly for availability, technical specifications, safety data sheets, and delivery options tailored to your specific industrial requirements and location within Europe.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.