4-methylphenol
C7H8O
Consulting for 4-methylphenol
Our experts support you with application, dosage, and compliance.
Identification
- CAS Number
- 106-44-5
- EC Number
- 203-398-6
- UN Number
- 3455
- Index Number
- 604-004-00-9
- PubChem CID
- 2879
Physical-chemical properties
- Molecular Formula
- C7H8O
- Molar Mass
- 108.14 g/mol
- IUPAC Name
- 4-methylphenol
Chemical Identifiers
- InChI
- InChI=1S/C7H8O/c1-6-2-4-7(8)5-3-6/h2-5,8H,1H3
- InChI Key
- IWDCLRJOBJJRNH-UHFFFAOYSA-N
Overview
4-methylphenol (CAS 106-44-5) is a methylated phenolic compound with antiseptic properties and corrosive characteristics. 4-methylphenol, also known as para-cresol, is an organic compound belonging to the cresol family of methylphenols. This colorless to pale yellow crystalline solid exhibits a characteristic phenolic odor and serves as an important intermediate in various chemical processes. With its molecular formula C7H8O and molar mass of 108.14 g/mol, this compound demonstrates significant biological activity and finds extensive use in industrial applications. The substance presents considerable safety considerations, classified under GHS pictograms GHS06 and GHS05 with a "Danger" signal word. Its classification as Acute Tox. 3 and Skin Corr. 1B indicates both acute toxicity and skin corrosive properties, requiring careful handling protocols and appropriate personal protective equipment. The ADR classification of 6.1 designates it as a toxic substance for transportation purposes. From a chemical perspective, 4-methylphenol shares structural similarities with other methylated phenols such as 3,5-dimethylphenol, though it exhibits distinct reactivity patterns due to its para-substitution. The compound demonstrates typical phenolic reactivity, including oxidation susceptibility and ability to form various derivatives. Primary industrial applications include its use as a disinfectant and antiseptic agent in pharmaceutical formulations, as an intermediate in the synthesis of antioxidants for rubber and plastics, and in the production of specialized resins and polymers. The compound also serves as a precursor for various fine chemicals and pharmaceutical intermediates. OYSI maintains reliable supply chains for 4-methylphenol, ensuring consistent availability for European industrial customers requiring this essential chemical intermediate.
Safety & Classification
Acute Tox. 3 *; Acute Tox. 3 *; Skin Corr. 1B
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Skin Contact
Measures if substance contacts the skin
Eye Contact
Measures if substance gets into the eyes
First Aid Actions
- +P305IF IN EYES:
- +P351Rinse cautiously with water for several minutes.
- +P338Remove contact lenses, if present and easy to do. Continue rinsing.
- +P313Get medical advice/attention.
Related hazard statements:
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 3455 |
| ADR Class | 6.1 |
| Packing Group | II |
| Tunnel Code | D/E |
| Proper Shipping Name | p-Cresol, flüssig* |
| Marine Pollutant | No |
Frequently Asked Questions
What is 4-methylphenol?
4-methylphenol is an organic chemical compound with the molecular formula C7H8O and CAS number 106-44-5. Also known as para-cresol, it belongs to the phenol family and has a molecular weight of 108.14 g/mol. This aromatic compound features a hydroxyl group (-OH) attached to a benzene ring with a methyl group in the para position. It is classified as a hazardous substance with acute toxicity and corrosive properties.
What are the physicochemical properties of 4-methylphenol?
4-methylphenol appears as white to pale yellow crystals or crystalline powder at room temperature. It has a characteristic phenolic odor and melts at approximately 34-36°C. The compound is moderately soluble in water and highly soluble in organic solvents such as ethanol, ether, and benzene. It exhibits acidic properties due to its phenolic nature and can form salts with bases. The substance is stable under normal conditions but may discolor upon exposure to light and air.
What is 4-methylphenol used for?
4-methylphenol serves as an important intermediate in chemical synthesis and manufacturing processes. It is primarily used in the production of antioxidants, particularly BHT (butylated hydroxytoluene), which is widely used as a food preservative and industrial antioxidant. Additionally, it finds applications in the manufacture of pharmaceuticals, pesticides, fragrances, and polymer additives. The compound is also utilized in resin production and as a disinfectant in certain industrial applications.
How to handle 4-methylphenol safely?
4-methylphenol requires careful handling due to its corrosive and toxic properties. Personnel must wear appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid direct skin and eye contact as the substance can cause severe burns and tissue damage. Emergency eyewash stations and safety showers should be readily accessible in work areas.
How to store 4-methylphenol correctly?
4-methylphenol should be stored in tightly sealed containers in a cool, dry, and well-ventilated area away from heat sources, ignition sources, and direct sunlight. Storage temperature should be kept below 25°C to prevent melting and vapor formation. The substance should be kept away from strong oxidizing agents, strong bases, and incompatible materials. Storage areas must be equipped with appropriate spill containment measures and should be accessible only to trained personnel.
What to do in case of contact with 4-methylphenol?
Immediate action is required in case of contact with 4-methylphenol. For skin contact, remove contaminated clothing and flush the affected area with copious amounts of water for at least 15 minutes. In case of eye contact, rinse immediately with water for at least 15 minutes and seek medical attention. If inhaled, move the person to fresh air and provide respiratory support if needed. For ingestion, do not induce vomiting and seek immediate medical attention.
How to dispose of 4-methylphenol appropriately?
4-methylphenol must be disposed of as hazardous waste in accordance with local, national, and international regulations. The substance cannot be disposed of in regular waste streams or sewerage systems due to its toxic and corrosive properties. Disposal should be carried out by licensed waste management companies specialized in handling hazardous chemicals. Small quantities may be neutralized under controlled conditions by qualified personnel before disposal, following appropriate environmental regulations and safety protocols.
How to transport 4-methylphenol?
4-methylphenol is classified as dangerous goods under ADR regulations with class 6.1 (toxic substances) and packing group II. Transportation requires proper packaging in UN-approved containers with appropriate labeling including GHS06 and GHS05 pictograms and 'Danger' signal word. Shipping documents must include the proper shipping name, UN number, and hazard class. Only authorized carriers with proper training and equipment should handle the transportation of this substance.
Is 4-methylphenol subject to specific regulations?
4-methylphenol is subject to various chemical regulations including REACH registration requirements in Europe and CLP classification obligations. The substance is classified with hazard classes Acute Tox. 3 and Skin Corr. 1B, requiring specific labeling and safety data sheets. While not currently listed as an SVHC (Substance of Very High Concern), it must comply with occupational exposure limits and environmental discharge restrictions. Users must ensure proper risk assessment and implementation of appropriate risk management measures.
Where to buy 4-methylphenol in Europe?
4-methylphenol is available through OYSI, a trusted European distributor of specialty chemicals serving industrial and professional customers across Europe. OYSI provides high-quality 4-methylphenol with complete documentation including safety data sheets and certificates of analysis. As an established chemical distributor, OYSI ensures compliance with European regulations and offers reliable supply chain management. Contact OYSI directly for pricing, availability, and technical support for your 4-methylphenol requirements.
Services for 4-methylphenol
Order 4-methylphenol
Fast delivery across Europe
SDS Service
Request Safety Data Sheet for 4-methylphenol
Technical Consulting
Application advice for 4-methylphenol
REACH Safety Data Sheet
REACH Compliance Service
Digital Product Passport
EU-compliant product documentation
ADR Consulting for 4-methylphenol
4-methylphenol is a dangerous good. We support you with labeling, packaging, and transport documentation.
Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.