4-methylphenol

4-methylphenol is an organic chemical compound with the molecular formula C7H8O and CAS number 106-44-5. It belongs to the phenol family and has a molecular weight of 108.14 g/mol. This aromatic compound is characterized by a methyl group attached to the fourth position of the phenol ring. It is classified as a hazardous substance with acute toxicity and skin corrosion properties, requiring careful handling in industrial applications.

4-methylphenol is typically a crystalline solid at room temperature with a characteristic phenolic odor. It appears as white to pale yellow crystals that can darken upon exposure to light and air. The compound is moderately soluble in water and highly soluble in organic solvents such as ethanol and ether. It has a melting point around 34-36°C and exhibits typical phenolic chemical reactivity including electrophilic aromatic substitution reactions.

4-methylphenol is primarily used as an intermediate in the production of antioxidants, pharmaceuticals, and agrochemicals. It serves as a building block for synthesizing butylated hydroxytoluene (BHT), a widely used antioxidant in food and industrial applications. The compound is also utilized in the manufacture of resins, dyes, and disinfectants. In the pharmaceutical industry, it acts as a precursor for various active ingredients and antiseptic formulations.

4-methylphenol requires strict safety precautions due to its Acute Tox. 3 and Skin Corr. 1B classifications. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and protective clothing covering all skin areas. Work in well-ventilated areas or under fume hoods to avoid inhalation. Prevent direct skin and eye contact as the substance can cause severe burns. Always wash hands thoroughly after handling and ensure emergency eyewash stations are accessible.

4-methylphenol should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Keep containers upright and protected from physical damage. Store separately from strong oxidizing agents, strong bases, and incompatible materials. Maintain storage temperatures below 25°C to prevent degradation. Ensure storage areas have appropriate spill containment measures and are accessible only to trained personnel with proper safety equipment.

Skin contact with 4-methylphenol requires immediate removal of contaminated clothing and thorough washing with plenty of water for at least 15 minutes. For eye contact, flush immediately with clean water for 15-20 minutes while holding eyelids open. If inhaled, move the person to fresh air immediately. In case of ingestion, do not induce vomiting and rinse mouth with water. Seek immediate medical attention for all exposure routes due to the substance's corrosive and toxic properties.

4-methylphenol disposal must comply with local and national hazardous waste regulations as it is classified as dangerous waste. The substance should never be disposed of down drains or in regular waste streams. Contact licensed hazardous waste disposal companies for proper treatment, which typically involves high-temperature incineration in approved facilities. Small quantities may require neutralization before disposal. Always consult local environmental authorities and follow waste classification codes for phenolic compounds.

4-methylphenol is classified under ADR as Class 6.1 (toxic substances), Packing Group II, indicating moderate danger during transport. It requires appropriate UN-approved packaging and labeling with GHS06 (skull and crossbones) and GHS05 (corrosion) pictograms along with 'Danger' signal word. Transportation must comply with ADR regulations for toxic substances, including proper documentation, vehicle placarding, and driver training. Only authorized carriers experienced in hazardous material transport should handle shipments.

4-methylphenol is subject to European REACH regulation requiring registration for import/manufacture above 1 ton per year. It falls under CLP regulation with mandatory hazard classification as Acute Tox. 3 and Skin Corr. 1B. The substance is not currently listed as SVHC (Substance of Very High Concern). Industrial users must comply with occupational exposure limits and implement appropriate risk management measures. Some applications may require additional authorizations depending on end-use and concentration levels.

4-methylphenol is available through OYSI, a specialized European distributor of industrial chemicals. OYSI provides high-quality 4-methylphenol with proper documentation including safety data sheets and certificates of analysis. As an established chemical distributor, OYSI ensures compliance with European regulations including REACH registration and CLP labeling requirements. Contact OYSI directly for availability, technical specifications, packaging options, and delivery throughout Europe for your industrial chemical needs.