N'-(4-chloro-2-methylphenyl)-N,N-dimethylmethanimidamide

C10H13ClN2

CAS6164-98-3
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
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Identification

CAS Number
6164-98-3
EC Number
228-200-5
UN Number
2761
Index Number
650-007-00-3
PubChem CID
22544

Physical-chemical properties

Molecular Formula
C10H13ClN2
Molar Mass
196.67 g/mol
IUPAC Name
N'-(4-chloro-2-methylphenyl)-N,N-dimethylmethanimidamide

Chemical Identifiers

InChI
InChI=1S/C10H13ClN2/c1-8-6-9(11)4-5-10(8)12-7-13(2)3/h4-7H,1-3H3
InChI Key
STUSTWKEFDQFFZ-UHFFFAOYSA-N

Overview

N'-(4-chloro-2-methylphenyl)-N,N-dimethylmethanimidamide (CAS 6164-98-3) is a chlorinated aromatic amidine compound with selective biological activity and industrial chemical applications. This organic compound belongs to the formamidine family and features a distinctive molecular structure combining a chlorinated methylphenyl group with a dimethylated amidine moiety. With a molecular formula of C10H13ClN2 and molecular weight of 196.67 g/mol, this substance exhibits specific chemical properties that make it valuable in various industrial processes. The compound is classified under EC number 228-200-5 and requires careful handling due to its toxicological profile. The substance presents significant safety considerations, classified as a Category 2 carcinogen and Category 4 acute toxicant. It poses environmental risks as an aquatic acute and chronic hazard, requiring appropriate containment and disposal measures. The compound carries GHS pictograms GHS08, GHS07, and GHS09, with a "Warning" signal word, and falls under ADR transport class 6.1 for toxic substances. Industrial applications typically include use as an intermediate in pharmaceutical synthesis, agricultural chemical production, and specialty chemical manufacturing. The compound's structural similarity to other amidine derivatives allows for specific reaction pathways in organic synthesis. Like 1,2-diphenylguanidine, which serves various industrial functions, this formamidine derivative offers unique reactivity patterns for specialized chemical processes. OYSI maintains reliable supply chains for this technical chemical, ensuring consistent availability for qualified industrial customers requiring high-purity formamidine compounds for their manufacturing operations.

Safety & Classification

Warning
Classification:

Carc. 2; Acute Tox. 4 *; Acute Tox. 4 *; Aquatic Acute 1; Aquatic Chronic 1

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H351

Suspected of causing cancer.

H312

Harmful in contact with skin.

H302

Harmful if swallowed.

H400

Very toxic to aquatic life.

H410

Very toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2761
ADR Class6.1
Packing GroupIII
Tunnel CodeE
Proper Shipping NameChlordimeform (ISO), fest
Marine PollutantNo

Frequently Asked Questions

What is N'-(4-chloro-2-methylphenyl)-N,N-dimethylmethanimidamide?

N'-(4-chloro-2-methylphenyl)-N,N-dimethylmethanimidamide is an organic chemical compound with the molecular formula C10H13ClN2 and CAS number 6164-98-3. This substance has a molecular weight of 196.67 g/mol and belongs to the class of substituted anilines. It is classified as a potential carcinogen (Category 2) and presents acute toxicity hazards. The compound also poses significant environmental risks, being classified as highly hazardous to aquatic life with long-lasting effects.

What are the physicochemical properties of N'-(4-chloro-2-methylphenyl)-N,N-dimethylmethanimidamide?

N'-(4-chloro-2-methylphenyl)-N,N-dimethylmethanimidamide is a solid organic compound at room temperature with a molecular weight of 196.67 g/mol. The substance contains a chlorinated aromatic ring with methyl and dimethylmethanimidamide substituents, giving it specific chemical reactivity patterns. Its structure suggests moderate lipophilicity due to the aromatic ring and chlorine substitution. Specific physical properties such as melting point, boiling point, and solubility data would require detailed technical documentation for precise values.

What is N'-(4-chloro-2-methylphenyl)-N,N-dimethylmethanimidamide used for?

N'-(4-chloro-2-methylphenyl)-N,N-dimethylmethanimidamide is primarily used as an intermediate in organic synthesis and pharmaceutical research. Given its chemical structure, it may serve as a building block for more complex molecules in medicinal chemistry applications. The compound's specific substitution pattern makes it valuable for developing various chemical derivatives. Industrial applications typically involve controlled synthesis processes where its unique molecular structure contributes to the formation of target compounds in research and development settings.

How to handle N'-(4-chloro-2-methylphenyl)-N,N-dimethylmethanimidamide safely?

N'-(4-chloro-2-methylphenyl)-N,N-dimethylmethanimidamide requires careful handling due to its carcinogenic potential and acute toxicity. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and appropriate respiratory protection. Work should be conducted in well-ventilated areas or under fume hoods to minimize inhalation exposure. Avoid skin contact and ingestion completely. Use appropriate handling tools and ensure proper training for all personnel. Emergency procedures should be readily available, and exposure monitoring may be necessary depending on usage quantities and frequency.

How to store N'-(4-chloro-2-methylphenyl)-N,N-dimethylmethanimidamide correctly?

N'-(4-chloro-2-methylphenyl)-N,N-dimethylmethanimidamide should be stored in a cool, dry, well-ventilated area away from incompatible materials. Keep containers tightly sealed and properly labeled according to GHS requirements. Storage areas should be equipped with appropriate containment measures and restricted access due to the substance's carcinogenic classification. Avoid exposure to heat, moisture, and reactive chemicals. Regular inventory checks and proper segregation from other hazardous materials are essential. Temperature-controlled storage may be beneficial for maintaining product stability and quality.

What to do in case of contact with N'-(4-chloro-2-methylphenyl)-N,N-dimethylmethanimidamide?

Immediate action is required for any contact with N'-(4-chloro-2-methylphenyl)-N,N-dimethylmethanimidamide due to its toxicity. For skin contact, remove contaminated clothing and wash affected areas thoroughly with soap and water for at least 15 minutes. In case of eye contact, flush immediately with clean water for 15-20 minutes. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical attention. Contact emergency services and provide the safety data sheet to medical personnel for proper treatment guidance.

How to dispose of N'-(4-chloro-2-methylphenyl)-N,N-dimethylmethanimidamide appropriately?

N'-(4-chloro-2-methylphenyl)-N,N-dimethylmethanimidamide must be disposed of as hazardous waste through licensed waste management facilities. The substance's carcinogenic properties and environmental hazard classification require special handling procedures. Incineration at high temperatures in authorized facilities is typically the preferred disposal method. Never dispose of this material in regular waste streams, sewers, or the environment. Consult local environmental regulations and waste disposal companies specializing in hazardous chemical waste. Proper documentation and waste tracking procedures must be followed.

How to transport N'-(4-chloro-2-methylphenyl)-N,N-dimethylmethanimidamide?

N'-(4-chloro-2-methylphenyl)-N,N-dimethylmethanimidamide is classified under ADR Class 6.1 (Toxic substances), Packing Group III for transportation purposes. This classification requires specific packaging, labeling, and documentation according to dangerous goods regulations. Appropriate UN-specification packaging must be used, and vehicles must display proper hazard placards. Drivers require ADR certification for transporting toxic substances. Shipping documentation must include proper shipping names, hazard classes, and emergency contact information. Transport should avoid extreme temperatures and ensure secure containment to prevent releases.

Is N'-(4-chloro-2-methylphenyl)-N,N-dimethylmethanimidamide subject to specific regulations?

N'-(4-chloro-2-methylphenyl)-N,N-dimethylmethanimidamide is subject to multiple regulatory frameworks including REACH registration requirements in Europe and CLP classification obligations. Its carcinogenic classification (Category 2) triggers specific labeling and safety data sheet requirements under GHS/CLP regulations. The substance requires proper hazard communication with GHS08, GHS07, and GHS09 pictograms and 'Warning' signal word. Environmental regulations apply due to its aquatic toxicity classification. Users must comply with occupational exposure limits and workplace safety regulations depending on local jurisdiction requirements.

Where to buy N'-(4-chloro-2-methylphenyl)-N,N-dimethylmethanimidamide in Europe?

N'-(4-chloro-2-methylphenyl)-N,N-dimethylmethanimidamide is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides this substance to qualified industrial and research customers with proper regulatory compliance and technical support. As a hazardous chemical with carcinogenic properties, purchases require appropriate business credentials and intended use documentation. OYSI ensures proper packaging, labeling, and transportation according to ADR regulations. Contact OYSI directly for availability, technical specifications, and regulatory compliance documentation to support your specific application requirements.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.