N'-(4-chloro-2-methylphenyl)-N,N-dimethylmethanimidamide

C10H13ClN2

CAS6164-98-3
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
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Identification

CAS Number
6164-98-3
EC Number
228-200-5
UN Number
2761
Index Number
650-007-00-3
PubChem CID
22544

Physical-chemical properties

Molecular Formula
C10H13ClN2
Molar Mass
196.67 g/mol
IUPAC Name
N'-(4-chloro-2-methylphenyl)-N,N-dimethylmethanimidamide

Chemical Identifiers

InChI
InChI=1S/C10H13ClN2/c1-8-6-9(11)4-5-10(8)12-7-13(2)3/h4-7H,1-3H3
InChI Key
STUSTWKEFDQFFZ-UHFFFAOYSA-N

Overview

N'-(4-chloro-2-methylphenyl)-N,N-dimethylmethanimidamide (CAS 6164-98-3) is an aromatic amidine compound with chlorinated phenyl and dimethylamino functional groups. This specialized chemical intermediate, with molecular formula C10H13ClN2 and molecular weight 196.67 g/mol, belongs to the formamidine class of organic compounds. The structure features a 4-chloro-2-methylphenyl group linked to a dimethylmethanimidamide moiety, creating a versatile building block for various synthetic applications. The compound's EC number 228-200-5 ensures regulatory compliance across European markets. Safety considerations are paramount when handling this substance, as it carries significant hazard classifications including carcinogenicity category 2 and acute toxicity category 4. The presence of GHS08, GHS07, and GHS09 pictograms indicates serious health hazards, general toxicity, and environmental dangers respectively. Its ADR class 6.1 classification requires specialized transport protocols for toxic substances. The compound also presents aquatic toxicity concerns, classified as both acute and chronic aquatic hazard category 1. Industrial applications typically involve its use as a chemical intermediate in pharmaceutical synthesis, agrochemical production, and specialty chemical manufacturing. The compound serves as a precursor in the development of bioactive molecules and can function as a building block in multi-step organic synthesis processes. Its structural similarity to other nitrogen-containing compounds like 1,2-diphenylguanidine makes it valuable in comparative synthetic chemistry applications. OYSI maintains reliable supply chains for this technical grade chemical, ensuring consistent availability for qualified industrial customers requiring this specialized formamidine derivative for their manufacturing processes.

Safety & Classification

Warning
Classification:

Carc. 2; Acute Tox. 4 *; Acute Tox. 4 *; Aquatic Acute 1; Aquatic Chronic 1

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H351

Suspected of causing cancer.

H312

Harmful in contact with skin.

H302

Harmful if swallowed.

H400

Very toxic to aquatic life.

H410

Very toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2761
ADR Class6.1
Packing GroupIII
Tunnel CodeE
Proper Shipping NameChlordimeform (ISO), fest
Marine PollutantNo

Frequently Asked Questions

What is N'-(4-chloro-2-methylphenyl)-N,N-dimethylmethanimidamide?

N'-(4-chloro-2-methylphenyl)-N,N-dimethylmethanimidamide is an organic chemical compound with the molecular formula C10H13ClN2 and CAS number 6164-98-3. This substance has a molecular weight of 196.67 g/mol and belongs to the class of substituted aromatic amidines. It is classified as a category 2 carcinogen and presents acute toxicity hazards. The compound also poses significant environmental risks to aquatic ecosystems, requiring careful handling and disposal procedures.

What are the physicochemical properties of N'-(4-chloro-2-methylphenyl)-N,N-dimethylmethanimidamide?

N'-(4-chloro-2-methylphenyl)-N,N-dimethylmethanimidamide is a chlorinated organic compound with a molecular weight of 196.67 g/mol and molecular formula C10H13ClN2. As an aromatic amidine derivative, it typically exists as a solid at room temperature. The presence of both chlorine substitution and dimethylamino groups influences its solubility characteristics and chemical reactivity. Specific physical properties such as melting point, boiling point, and exact solubility data should be confirmed through technical documentation.

What is N'-(4-chloro-2-methylphenyl)-N,N-dimethylmethanimidamide used for?

N'-(4-chloro-2-methylphenyl)-N,N-dimethylmethanimidamide is primarily used as a chemical intermediate in organic synthesis and pharmaceutical research applications. Its aromatic amidine structure makes it valuable for developing various chemical compounds and active pharmaceutical ingredients. Due to its carcinogenic classification and toxicity profile, its use is restricted to professional and industrial applications with appropriate safety measures. The compound requires specialized handling procedures and is typically used in controlled laboratory or manufacturing environments.

How to handle N'-(4-chloro-2-methylphenyl)-N,N-dimethylmethanimidamide safely?

N'-(4-chloro-2-methylphenyl)-N,N-dimethylmethanimidamide requires strict safety protocols due to its carcinogenic and toxic properties. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and respiratory protection. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid skin contact and ingestion completely. Use appropriate engineering controls and ensure personnel are trained in handling procedures. Follow all safety data sheet recommendations and maintain emergency response procedures readily available.

How to store N'-(4-chloro-2-methylphenyl)-N,N-dimethylmethanimidamide correctly?

N'-(4-chloro-2-methylphenyl)-N,N-dimethylmethanimidamide must be stored in a cool, dry, well-ventilated area away from incompatible materials. Keep containers tightly sealed and protected from moisture and direct sunlight. Due to its carcinogenic classification, storage areas should be clearly labeled and access restricted to authorized personnel only. Store away from oxidizing agents and strong acids. Maintain appropriate secondary containment and ensure storage areas comply with local regulations for hazardous substances.

What to do in case of contact with N'-(4-chloro-2-methylphenyl)-N,N-dimethylmethanimidamide?

Immediate action is required for any contact with N'-(4-chloro-2-methylphenyl)-N,N-dimethylmethanimidamide due to its toxic properties. For skin contact, remove contaminated clothing and rinse thoroughly with water for at least 15 minutes. If inhaled, move to fresh air immediately and seek medical attention. For eye contact, flush with water for at least 15 minutes and remove contact lenses if present. If ingested, do not induce vomiting and seek immediate medical attention. Always consult emergency services for serious exposures.

How to dispose of N'-(4-chloro-2-methylphenyl)-N,N-dimethylmethanimidamide appropriately?

N'-(4-chloro-2-methylphenyl)-N,N-dimethylmethanimidamide must be disposed of through licensed hazardous waste disposal facilities due to its carcinogenic and environmental hazard classifications. Never dispose of this substance through regular waste streams or sewerage systems. The compound's high aquatic toxicity requires specialized treatment to prevent environmental contamination. Contact authorized waste management companies familiar with handling carcinogenic substances. Maintain proper documentation for waste disposal and ensure compliance with local and European waste regulations.

How to transport N'-(4-chloro-2-methylphenyl)-N,N-dimethylmethanimidamide?

N'-(4-chloro-2-methylphenyl)-N,N-dimethylmethanimidamide is classified under ADR class 6.1 (toxic substances), packing group III for transportation purposes. This classification requires specific packaging, labeling, and documentation for road transport within Europe. Packages must display appropriate hazard labels and proper shipping names. Transportation must comply with ADR regulations for toxic substances, including driver training requirements and vehicle placarding. Ensure proper segregation from incompatible materials during transport and maintain emergency response information readily available.

Is N'-(4-chloro-2-methylphenyl)-N,N-dimethylmethanimidamide subject to specific regulations?

N'-(4-chloro-2-methylphenyl)-N,N-dimethylmethanimidamide is subject to extensive European chemical regulations including REACH registration requirements and CLP classification obligations. Its carcinogenic classification (Category 2) subjects it to specific labeling and safety data sheet requirements. While not currently listed as a Substance of Very High Concern (SVHC), its hazard profile may trigger additional regulatory scrutiny. Users must comply with occupational exposure limits, environmental discharge restrictions, and waste disposal regulations. Regular regulatory monitoring is recommended due to evolving chemical legislation.

Where to buy N'-(4-chloro-2-methylphenyl)-N,N-dimethylmethanimidamide in Europe?

N'-(4-chloro-2-methylphenyl)-N,N-dimethylmethanimidamide is available through OYSI, a specialized European distributor of technical chemicals. As a professional-grade chemical with significant hazard classifications, it is only supplied to qualified industrial and research customers with appropriate handling capabilities. OYSI ensures full regulatory compliance including proper documentation, safety data sheets, and transportation requirements. Due to the substance's hazardous nature, purchases require verification of legitimate use and appropriate safety infrastructure at the customer's facilities.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.