2,2-diphenyl-2-[(3S)-pyrrolidin-3-yl]acetonitrile;hydrobromide

2,2-diphenyl-2-[(3S)-pyrrolidin-3-yl]acetonitrile;hydrobromide is an organic chemical compound with the molecular formula C18H19BrN2 and CAS number 194602-27-2. This substance has a molecular weight of 343.3 g/mol and contains a pyrrolidine ring structure combined with diphenyl groups and a nitrile function, forming a hydrobromide salt. It is classified as a hazardous chemical requiring careful handling due to its toxicity and corrosive properties.

2,2-diphenyl-2-[(3S)-pyrrolidin-3-yl]acetonitrile;hydrobromide is a solid compound at room temperature with a molecular weight of 343.3 g/mol. As a hydrobromide salt, it typically exhibits good solubility in polar solvents like water and alcohols. The compound contains aromatic rings, a pyrrolidine heterocycle, and a nitrile group, contributing to its chemical stability. Specific physical properties such as melting point, color, and odor should be verified through technical data sheets from suppliers.

2,2-diphenyl-2-[(3S)-pyrrolidin-3-yl]acetonitrile;hydrobromide is primarily used as a research chemical and pharmaceutical intermediate. Its pyrrolidine-containing structure makes it valuable in medicinal chemistry for drug development and synthesis of bioactive compounds. The compound may serve as a building block in the preparation of more complex molecules or as a reference standard in analytical applications. Industrial applications are typically limited to specialized chemical synthesis and pharmaceutical research laboratories.

2,2-diphenyl-2-[(3S)-pyrrolidin-3-yl]acetonitrile;hydrobromide requires careful handling due to its Acute Tox. 4, Eye Dam. 1, and Skin Sens. 1 classifications. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and protective clothing. Work in well-ventilated areas or under fume hoods to avoid inhalation. Prevent skin and eye contact, as the substance can cause severe eye damage and skin sensitization. Always wash hands thoroughly after handling and follow standard laboratory safety protocols.

2,2-diphenyl-2-[(3S)-pyrrolidin-3-yl]acetonitrile;hydrobromide should be stored in tightly sealed containers in a cool, dry, and well-ventilated area away from heat sources and direct sunlight. Keep containers properly labeled and segregated from incompatible materials. Due to its hazardous classification, store in designated chemical storage areas with appropriate containment measures. Maintain storage temperatures as specified by the supplier and regularly inspect containers for signs of deterioration or leakage.

2,2-diphenyl-2-[(3S)-pyrrolidin-3-yl]acetonitrile;hydrobromide exposure requires immediate action due to its corrosive and toxic nature. For skin contact, immediately wash with plenty of water for at least 15 minutes and remove contaminated clothing. In case of eye contact, flush immediately with water for at least 15 minutes and seek medical attention due to potential severe eye damage. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical attention. Always consult the safety data sheet for complete first aid procedures.

2,2-diphenyl-2-[(3S)-pyrrolidin-3-yl]acetonitrile;hydrobromide disposal must comply with local, national, and international hazardous waste regulations due to its toxic and environmentally harmful properties. Contact licensed hazardous waste disposal companies for proper treatment and disposal. Never dispose of this substance down drains, in regular waste streams, or into the environment. Contaminated containers, clothing, and materials should also be treated as hazardous waste. Maintain proper documentation of waste disposal activities as required by applicable regulations.

2,2-diphenyl-2-[(3S)-pyrrolidin-3-yl]acetonitrile;hydrobromide is classified as ADR Class 9 (Miscellaneous dangerous substances), Packing Group III for transportation purposes. This classification requires appropriate packaging, labeling, and documentation according to dangerous goods regulations. Packages must display proper hazard labels and shipping names. Transportation should only be carried out by qualified personnel familiar with dangerous goods handling procedures. Ensure compliance with national and international transportation regulations including proper vehicle requirements and route restrictions.

2,2-diphenyl-2-[(3S)-pyrrolidin-3-yl]acetonitrile;hydrobromide is subject to various chemical regulations including REACH registration requirements in Europe and CLP classification obligations. The substance is not currently listed as an SVHC (Substance of Very High Concern) under REACH. However, its hazardous classification requires compliance with occupational health and safety regulations, chemical safety assessments, and proper labeling according to GHS standards. Users must maintain safety data sheets and implement appropriate risk management measures in accordance with applicable chemical legislation.

2,2-diphenyl-2-[(3S)-pyrrolidin-3-yl]acetonitrile;hydrobromide is available through OYSI, a specialized European distributor of chemical products serving research and industrial customers across Europe. OYSI provides quality chemical products with proper documentation, safety data sheets, and regulatory compliance support. The compound can also be sourced from other specialized chemical suppliers focusing on research chemicals and pharmaceutical intermediates. When purchasing, ensure suppliers provide appropriate certificates of analysis, safety documentation, and comply with applicable regulations.