2,2-diphenyl-2-[(3S)-pyrrolidin-3-yl]acetonitrile;hydrobromide

2,2-diphenyl-2-[(3S)-pyrrolidin-3-yl]acetonitrile;hydrobromide is an organic chemical compound with CAS number 194602-27-2 and molecular formula C18H19BrN2. This compound features a pyrrolidine ring structure with diphenyl and acetonitrile functional groups, existing as a hydrobromide salt. With a molecular weight of 343.3 g/mol, it belongs to the class of nitrogen-containing heterocyclic compounds and is classified as hazardous with multiple safety classifications including acute toxicity and eye damage properties.

2,2-diphenyl-2-[(3S)-pyrrolidin-3-yl]acetonitrile;hydrobromide exhibits typical properties of an organic hydrobromide salt with a molecular weight of 343.3 g/mol. As a hydrobromide salt, it typically appears as a crystalline solid at room temperature and shows enhanced water solubility compared to its free base form. The compound contains aromatic rings (diphenyl groups), a nitrile group, and a pyrrolidine ring, contributing to its chemical stability and specific reactivity profile under standard laboratory conditions.

2,2-diphenyl-2-[(3S)-pyrrolidin-3-yl]acetonitrile;hydrobromide is primarily used as a chemical intermediate in pharmaceutical research and development. The compound's specific stereochemistry and functional groups make it valuable for synthetic organic chemistry applications, particularly in the development of bioactive molecules. Its pyrrolidine structure and chiral center are commonly found in pharmaceutical compounds, making it useful for medicinal chemistry research, drug discovery processes, and as a building block for more complex molecular structures.

2,2-diphenyl-2-[(3S)-pyrrolidin-3-yl]acetonitrile;hydrobromide requires careful handling due to its Acute Tox. 4, Eye Dam. 1, and Skin Sens. 1 classifications. Essential personal protective equipment includes chemical-resistant gloves, safety goggles or face shield, and protective clothing. Work in well-ventilated areas or under fume hoods to prevent inhalation. Avoid direct skin and eye contact, and never eat, drink, or smoke while handling. Wash hands thoroughly after use and ensure emergency eyewash stations are accessible in the work area.

2,2-diphenyl-2-[(3S)-pyrrolidin-3-yl]acetonitrile;hydrobromide should be stored in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Keep containers tightly closed and store in original packaging with proper labeling. Due to its hazard classifications, maintain segregation from incompatible materials and food products. Storage areas should have appropriate spill containment measures and restricted access. Regular inspection of containers for damage or deterioration is recommended, and inventory should follow first-in-first-out principles to ensure product integrity.

Immediate action is required for contact with 2,2-diphenyl-2-[(3S)-pyrrolidin-3-yl]acetonitrile;hydrobromide due to its Eye Dam. 1 classification. For eye contact, flush immediately with plenty of water for at least 15 minutes and seek immediate medical attention. For skin contact, remove contaminated clothing and wash affected area thoroughly with soap and water. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek medical attention. Always consult the safety data sheet and contact emergency services if severe symptoms occur.

2,2-diphenyl-2-[(3S)-pyrrolidin-3-yl]acetonitrile;hydrobromide must be disposed of as hazardous chemical waste through licensed waste management companies. Due to its Aquatic Chronic 2 classification, prevent release to waterways or soil. Container disposal should follow local and national regulations, with empty containers treated as hazardous waste. Incineration at approved high-temperature facilities is typically the preferred disposal method for organic compounds. Always consult local environmental regulations and maintain proper waste tracking documentation throughout the disposal process.

2,2-diphenyl-2-[(3S)-pyrrolidin-3-yl]acetonitrile;hydrobromide is classified as ADR Class 9 (Miscellaneous dangerous substances), Packing Group III for transportation. This classification requires appropriate UN-specification packaging, proper labeling with Class 9 hazard labels, and transport documentation including dangerous goods declarations. Vehicles must carry appropriate emergency equipment and drivers require dangerous goods training certification. The compound should be secured to prevent movement during transport and segregated according to dangerous goods compatibility requirements. Temperature-controlled transport may be necessary depending on storage requirements.

2,2-diphenyl-2-[(3S)-pyrrolidin-3-yl]acetonitrile;hydrobromide is subject to REACH regulation requirements in Europe, though it is not classified as a Substance of Very High Concern (SVHC). The compound falls under CLP regulation for hazard classification and labeling requirements, requiring appropriate GHS pictograms (GHS05, GHS07, GHS09) and safety data sheets. Transport regulations under ADR apply for shipping. Users must comply with occupational health and safety regulations, and environmental discharge limits may apply due to its aquatic toxicity classification.

2,2-diphenyl-2-[(3S)-pyrrolidin-3-yl]acetonitrile;hydrobromide is available through OYSI, a specialized European distributor of fine chemicals and pharmaceutical intermediates. OYSI provides this compound with full regulatory compliance, proper documentation, and safety data sheets meeting European standards. As an established chemical distributor, OYSI ensures product quality, appropriate packaging, and reliable supply chain management across Europe. Contact OYSI directly for availability, specifications, and technical support for your specific application requirements in research or industrial processes.