1H-indol-6-ol

1H-indol-6-ol is an organic compound belonging to the indole family with the molecular formula C8H7NO and a molecular weight of 133.15 g/mol. This chemical substance features a hydroxyl group attached to the 6-position of the indole ring structure. It is classified as a hazardous substance with acute toxicity, eye damage, skin sensitization, and aquatic toxicity properties. The compound is assigned CAS number 2380-86-1 and requires careful handling due to its danger classification.

1H-indol-6-ol exhibits typical properties of hydroxylated indole derivatives, appearing as a solid at room temperature. The compound contains both aromatic indole structure and phenolic hydroxyl functionality, which influences its solubility characteristics. Its molecular structure with C8H7NO formula and 133.15 g/mol molecular weight determines its physical behavior. Specific properties like melting point, boiling point, and exact solubility data should be confirmed through technical documentation or safety data sheets.

1H-indol-6-ol serves as an important intermediate in pharmaceutical and chemical synthesis applications. The compound is primarily used in research and development activities, particularly in the synthesis of more complex organic molecules and potential pharmaceutical compounds. Its indole structure makes it valuable for medicinal chemistry applications and as a building block in organic synthesis. Due to its specialized nature, it is typically used in professional laboratory and industrial settings rather than consumer applications.

1H-indol-6-ol requires careful handling with appropriate personal protective equipment including safety goggles, chemical-resistant gloves, and protective clothing due to its eye damage and skin sensitization properties. Work should be conducted in well-ventilated areas or under fume hoods to minimize inhalation risks. Avoid direct skin and eye contact, and ensure emergency eyewash stations are accessible. Personnel should be trained on the substance's acute toxicity (Category 4) and sensitization potential before handling.

1H-indol-6-ol should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from incompatible materials. Storage areas must be equipped with appropriate spill containment measures and restricted to authorized personnel only. Keep containers properly labeled with hazard information and ensure storage conditions prevent degradation or contamination. Regular inspection of storage containers is recommended to maintain product integrity and prevent leaks that could pose environmental risks.

In case of eye contact with 1H-indol-6-ol, immediately flush eyes with plenty of clean water for at least 15 minutes and seek medical attention due to its eye damage classification. For skin contact, remove contaminated clothing and wash affected area thoroughly with soap and water. If ingestion occurs, do not induce vomiting and seek immediate medical advice. In case of inhalation, move to fresh air immediately. Always consult the safety data sheet for specific first aid measures.

1H-indol-6-ol waste must be disposed of through licensed hazardous waste disposal facilities in accordance with local and national environmental regulations. The compound's classification as Aquatic Chronic 2 requires special consideration to prevent environmental contamination. Waste should be collected in appropriate containers, properly labeled, and never discharged into sewers or waterways. Consult local environmental authorities for specific disposal requirements and approved waste management contractors in your region.

1H-indol-6-ol is classified under ADR Class 9 (Miscellaneous dangerous substances), Packing Group III for transportation purposes. This classification requires appropriate packaging, labeling, and documentation during transport. Packages must bear the proper shipping name, UN number, and hazard labels according to ADR regulations. Transportation should only be conducted by qualified carriers familiar with dangerous goods regulations. Proper emergency response information must accompany shipments.

1H-indol-6-ol is subject to standard chemical safety regulations including REACH registration requirements in Europe and CLP classification and labeling regulations. The substance is not currently listed as a Substance of Very High Concern (SVHC). Suppliers must provide safety data sheets and proper hazard communication. Users must comply with occupational health and safety requirements, environmental protection measures, and proper waste disposal regulations. Import/export may require additional documentation depending on destination countries.

1H-indol-6-ol is available through OYSI, a specialized European distributor of chemical products. OYSI provides professional-grade chemicals to research institutions, laboratories, and industrial customers across Europe. As an established chemical supplier, OYSI ensures proper documentation, safety data sheets, and regulatory compliance for all products. Contact OYSI directly for availability, specifications, packaging options, and delivery information to your specific European location.