2-ethyl-2-methyl-1,3-thiazolidine
C6H13NS
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Identification
- CAS Number
- 694-64-4
- EC Number
- 404-500-3
- UN Number
- 3082
- Index Number
- 613-170-00-1
- PubChem CID
- 568373
Physical-chemical properties
- Molecular Formula
- C6H13NS
- Molar Mass
- 131.24 g/mol
- IUPAC Name
- 2-ethyl-2-methyl-1,3-thiazolidine
Chemical Identifiers
- InChI
- InChI=1S/C6H13NS/c1-3-6(2)7-4-5-8-6/h7H,3-5H2,1-2H3
- InChI Key
- AGSHBVNPPGEAMB-UHFFFAOYSA-N
Overview
2-ethyl-2-methyl-1,3-thiazolidine (CAS 694-64-4) is a heterocyclic organosulfur compound featuring a five-membered thiazolidine ring with ethyl and methyl substituents at the 2-position. This specialized chemical intermediate belongs to the thiazolidine family, characterized by its distinctive sulfur and nitrogen-containing ring structure. With the molecular formula C6H13NS and a molecular weight of 131.24 g/mol, this compound exhibits unique chemical properties that make it valuable in various industrial applications. The presence of both ethyl and methyl groups at the 2-position enhances its reactivity profile compared to simpler thiazolidine derivatives. From a safety perspective, 2-ethyl-2-methyl-1,3-thiazolidine requires careful handling due to its classification under multiple hazard categories. The compound is classified as Acute Tox. 4, indicating moderate acute toxicity, and Eye Dam. 1, signifying severe eye damage potential. It also demonstrates skin sensitization properties (Skin Sens. 1) and poses chronic aquatic toxicity risks (Aquatic Chronic 2). These characteristics necessitate appropriate personal protective equipment and containment measures during handling and processing. Industrial applications of this thiazolidine derivative typically include its use as a chemical intermediate in pharmaceutical synthesis, where its heterocyclic structure serves as a building block for more complex molecules. It also finds utility in agrochemical formulations and specialty chemical manufacturing. While structurally distinct from compounds like 1H-indol-6-ol, both substances share applications in pharmaceutical intermediate chemistry, though through different synthetic pathways. The compound is transported under ADR Class 9 (miscellaneous dangerous substances), reflecting its specialized handling requirements. OYSI maintains reliable supply chains for this technical grade chemical, supporting European industrial customers with consistent quality and regulatory compliance.
Safety & Classification
Acute Tox. 4 *; Eye Dam. 1; Skin Sens. 1; Aquatic Chronic 2
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Skin Contact
Measures if substance contacts the skin
First Aid Actions
- +P302IF ON SKIN:
- +P352Wash with plenty of water.
- +P361Take off immediately all contaminated clothing.
- +P313Get medical advice/attention.
Related hazard statements:
Eye Contact
Measures if substance gets into the eyes
First Aid Actions
- +P305IF IN EYES:
- +P351Rinse cautiously with water for several minutes.
- +P338Remove contact lenses, if present and easy to do. Continue rinsing.
- +P313Get medical advice/attention.
Related hazard statements:
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 3082 |
| ADR Class | 9 |
| Packing Group | III |
| Tunnel Code | - |
| Proper Shipping Name | 2-Ethyl-2-methyl-1,3-thiazolidin |
| Marine Pollutant | No |
Frequently Asked Questions
What is 2-ethyl-2-methyl-1,3-thiazolidine?
2-ethyl-2-methyl-1,3-thiazolidine is a heterocyclic organic compound containing sulfur and nitrogen with the molecular formula C6H13NS. This thiazolidine derivative features a five-membered ring structure with ethyl and methyl substituents at the 2-position. With a molecular weight of 131.24 g/mol and CAS number 694-64-4, it is classified as a hazardous chemical requiring careful handling due to its toxicity, eye damage potential, and skin sensitization properties.
What are the physicochemical properties of 2-ethyl-2-methyl-1,3-thiazolidine?
2-ethyl-2-methyl-1,3-thiazolidine is typically a liquid at room temperature with characteristic chemical properties of thiazolidine compounds. As an organic sulfur-nitrogen heterocycle, it exhibits moderate polarity due to the heteroatoms in its ring structure. The compound's physical state, specific gravity, boiling point, and solubility characteristics should be confirmed through technical documentation, as these parameters are essential for proper handling and application in industrial processes.
What is 2-ethyl-2-methyl-1,3-thiazolidine used for?
2-ethyl-2-methyl-1,3-thiazolidine serves as a chemical intermediate in organic synthesis and pharmaceutical manufacturing. Its thiazolidine ring structure makes it valuable in the production of various fine chemicals, potentially including pharmaceutical compounds, agrochemicals, and specialty chemical products. The compound may also function as a building block in research and development applications where sulfur-nitrogen heterocycles are required for molecular design and synthetic pathways.
How to handle 2-ethyl-2-methyl-1,3-thiazolidine safely?
2-ethyl-2-methyl-1,3-thiazolidine requires careful handling with appropriate personal protective equipment due to its Danger signal word classification. Essential PPE includes chemical-resistant gloves, safety goggles or face shield (due to Eye Dam. 1 classification), and protective clothing to prevent skin contact. Work in well-ventilated areas or use fume extraction systems, as the compound poses acute toxicity risks and can cause skin sensitization. Always follow established safety protocols and emergency procedures.
How to store 2-ethyl-2-methyl-1,3-thiazolidine correctly?
2-ethyl-2-methyl-1,3-thiazolidine should be stored in tightly sealed, chemically compatible containers in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Storage areas must be equipped with appropriate spill containment measures and emergency equipment. Keep containers properly labeled with GHS pictograms (GHS05, GHS07, GHS09) and safety information. Access should be restricted to trained personnel only, and inventory should be managed using first-in-first-out principles to maintain product integrity.
What to do in case of contact with 2-ethyl-2-methyl-1,3-thiazolidine?
Immediate action is critical due to the compound's Eye Dam. 1 and skin sensitization properties. For eye contact, rinse immediately with plenty of water for at least 15 minutes and seek medical attention promptly. For skin contact, remove contaminated clothing and wash affected area thoroughly with soap and water. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek medical attention. Always consult the safety data sheet for complete first aid procedures and contact emergency services if necessary.
How to dispose of 2-ethyl-2-methyl-1,3-thiazolidine properly?
2-ethyl-2-methyl-1,3-thiazolidine must be disposed of as hazardous chemical waste in accordance with local, national, and EU regulations. The compound's Aquatic Chronic 2 classification requires special consideration to prevent environmental contamination. Contact licensed hazardous waste disposal companies for proper collection and treatment. Never discharge into sewers, water bodies, or soil. Empty containers should also be handled as hazardous waste unless properly decontaminated according to regulatory requirements.
How to transport 2-ethyl-2-methyl-1,3-thiazolidine?
2-ethyl-2-methyl-1,3-thiazolidine is classified as ADR Class 9 (Miscellaneous Dangerous Substances), Packing Group III for transportation purposes. This classification requires specific packaging, labeling, and documentation according to ADR regulations. Packages must bear appropriate hazard labels and be transported by qualified carriers with proper training and equipment. Shipping documentation must include the correct technical name, UN number, and hazard class information to ensure regulatory compliance throughout the European transport network.
Is 2-ethyl-2-methyl-1,3-thiazolidine subject to specific regulations?
2-ethyl-2-methyl-1,3-thiazolidine is subject to EU CLP Regulation for classification and labeling, requiring GHS pictograms and hazard statements on packaging. Under REACH regulation, it must be registered for commercial use above certain tonnage thresholds. The compound is not currently listed as an SVHC (Substance of Very High Concern). Users must comply with occupational safety regulations and may need to implement risk management measures based on its hazard classification and intended use applications.
Where to buy 2-ethyl-2-methyl-1,3-thiazolidine in Europe?
2-ethyl-2-methyl-1,3-thiazolidine is available through OYSI, a specialized European distributor of technical chemicals serving industrial customers across the continent. OYSI provides reliable supply chains, technical support, and regulatory compliance assistance for chemical procurement. As a professional chemical distributor, OYSI ensures proper packaging, documentation, and delivery of hazardous materials in accordance with European regulations. Contact OYSI directly for availability, specifications, and commercial terms tailored to your specific requirements.
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ADR Consulting for 2-ethyl-2-methyl-1,3-thiazolidine
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Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.