1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-one

1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-one is an organic chemical compound with the molecular formula C15H20FNO3 and CAS number 116256-11-2. This piperidine derivative has a molecular weight of 281.32 g/mol and contains fluorine, nitrogen, and oxygen functional groups. It is classified as a hazardous substance with multiple safety concerns including acute toxicity, eye damage potential, skin sensitization properties, and aquatic toxicity.

1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-one exhibits properties typical of organic compounds containing fluorinated aromatic rings and piperidine structures. The presence of the fluorophenoxy group influences its polarity and potential solubility characteristics. The methoxy and ketone functional groups contribute to its chemical reactivity. Specific physical properties such as melting point, boiling point, and exact solubility data would require detailed analytical characterization for precise determination.

1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-one is primarily used as an intermediate in pharmaceutical and fine chemical synthesis. Its piperidine structure makes it valuable in medicinal chemistry applications, particularly in the development of pharmaceutical compounds. The fluorophenoxy moiety provides specific binding properties that are useful in drug discovery research. Industrial applications may include its use as a building block for more complex organic molecules in specialized chemical manufacturing processes.

1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-one requires careful handling due to its classification as Acute Tox. 4, Eye Dam. 1, and Skin Sens. 1. Essential personal protective equipment includes chemical-resistant gloves, safety goggles or face shield, and appropriate respiratory protection. Work in well-ventilated areas or under fume hoods to minimize exposure. Avoid skin and eye contact, and prevent inhalation of vapors or dust. Ensure emergency shower and eyewash facilities are readily accessible.

1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-one should be stored in tightly sealed, chemically compatible containers in a cool, dry, well-ventilated area away from incompatible materials. Keep containers away from sources of ignition, heat, and direct sunlight. Store separately from strong oxidizing agents, acids, and bases to prevent unwanted reactions. Ensure storage areas have appropriate containment measures and are accessible only to trained personnel. Regular inspection of containers for integrity is recommended.

Immediate action is required upon contact with 1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-one due to its eye damage and skin sensitization potential. For skin contact, immediately wash with plenty of water for at least 15 minutes and remove contaminated clothing. For eye contact, rinse immediately with water for at least 15 minutes and seek medical attention. If inhaled, move to fresh air immediately. If ingested, do not induce vomiting and seek immediate medical attention. Always consult emergency services for serious exposures.

1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-one must be disposed of as hazardous waste in accordance with local, national, and EU regulations due to its toxicity classification and environmental concerns. Contact licensed hazardous waste disposal companies for proper treatment and disposal. Never dispose of this substance down drains, in regular waste, or release into the environment. Ensure proper documentation and waste tracking throughout the disposal process. Consult local environmental authorities for specific disposal requirements in your region.

1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-one is classified as ADR Class 9 (Miscellaneous dangerous substances), Packing Group III for transportation purposes. This classification requires specific packaging, labeling, and documentation according to international dangerous goods regulations. Packages must display appropriate hazard labels and proper shipping names. Transportation vehicles must carry emergency response information and appropriate safety equipment. Only trained personnel familiar with dangerous goods regulations should handle the shipping and transport of this substance.

1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-one is subject to EU REACH regulation requiring registration for manufacturing or importing quantities above one tonne annually. The substance is not currently listed as an SVHC (Substance of Very High Concern). CLP regulation governs its classification and labeling requirements, mandating GHS pictograms GHS05, GHS07, and GHS09 with 'Danger' signal word. National chemical regulations may impose additional requirements for handling, storage, and use in specific applications.

1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-one is available through OYSI, a European distributor specializing in technical chemicals and pharmaceutical intermediates. OYSI provides reliable supply chain solutions for laboratories, research institutions, and industrial customers across Europe. As an established chemical distributor, OYSI ensures proper handling, documentation, and regulatory compliance for hazardous substances. Contact OYSI directly for availability, technical specifications, safety documentation, and delivery options for your specific requirements.