2,2-dimethylpropan-1-ol

C5H12O

CAS75-84-3
GHS02 Gefahrensymbol: Entzündbar – Flamme
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
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Identification

CAS Number
75-84-3
EC Number
200-907-3
UN Number
1325
Index Number
603-006-00-7
PubChem CID
6404

Physical-chemical properties

Molecular Formula
C5H12O
Molar Mass
88.15 g/mol
IUPAC Name
2,2-dimethylpropan-1-ol

Chemical Identifiers

InChI
InChI=1S/C5H12O/c1-5(2,3)4-6/h6H,4H2,1-3H3
InChI Key
KPSSIOMAKSHJJG-UHFFFAOYSA-N

Overview

2,2-dimethylpropan-1-ol (CAS 75-84-3) is a branched primary alcohol with distinctive steric hindrance properties and industrial solvent applications. This tertiary branched alcohol, also known as neopentyl alcohol, represents a unique structural variant within the C5 alcohol family due to its highly substituted carbon framework. The compound features a primary hydroxyl group attached to a quaternary carbon center, creating significant steric bulk that influences both its physical properties and chemical reactivity patterns. With a molecular weight of 88.15 g/mol and formula C5H12O, this colorless liquid exhibits moderate volatility and distinctive solvent characteristics that distinguish it from linear pentanol isomers. From a safety perspective, 2,2-dimethylpropan-1-ol carries important handling considerations as classified under Flammable Liquid Category 3 and Acute Toxicity Category 4, requiring appropriate ventilation and fire prevention measures. The compound also presents specific target organ toxicity concerns, necessitating proper personal protective equipment during industrial processing. Its ADR Class 4.1 classification reflects the flammability hazards associated with transport and storage operations. Industrial applications primarily leverage its unique steric properties and moderate polarity. The compound serves as a specialized solvent in polymer chemistry, particularly for applications requiring reduced nucleophilicity compared to less hindered alcohols. Additionally, it functions as an intermediate in the synthesis of esters and ethers where steric control is paramount. Unlike structurally complex compounds such as 1,3,5,7-tetrazatricyclo[3.3.1.13,7]decane, neopentyl alcohol offers straightforward handling while maintaining distinctive reactivity profiles. OYSI maintains reliable European supply channels for 2,2-dimethylpropan-1-ol, supporting diverse industrial applications across the chemical processing sector with comprehensive technical documentation and safety data.

Safety & Classification

Warning
Classification:

Flam. Liq. 3; Acute Tox. 4 *; STOT SE 3

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H226

Flammable liquid and vapour.

H332

Harmful if inhaled.

H335

May cause respiratory irritation.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Harmful

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number1325
ADR Class4.1
Packing GroupII
Tunnel CodeE
Proper Shipping Name2,2-Dimethylpropan-1-ol
Marine PollutantNo

Frequently Asked Questions

What is 2,2-dimethylpropan-1-ol?

2,2-dimethylpropan-1-ol is a branched primary alcohol with the molecular formula C5H12O and CAS number 75-84-3. Also known as neopentyl alcohol, this compound features a highly branched structure with two methyl groups attached to the second carbon atom. With a molecular weight of 88.15 g/mol, it belongs to the family of pentyl alcohols and exhibits unique properties due to its sterically hindered structure.

What are the physicochemical properties of 2,2-dimethylpropan-1-ol?

2,2-dimethylpropan-1-ol is a colorless liquid at room temperature with a characteristic alcohol odor. Due to its branched structure, it has a relatively high melting point compared to linear alcohols and exhibits limited water solubility. The compound is soluble in most organic solvents including ethanol, ether, and hydrocarbons. Its highly branched structure affects its physical properties, making it more volatile than its linear isomers.

What is 2,2-dimethylpropan-1-ol used for?

2,2-dimethylpropan-1-ol serves as an important intermediate in organic synthesis and chemical manufacturing. It is primarily used in the production of esters, ethers, and other specialty chemicals. The compound finds applications in the pharmaceutical industry as a building block for active ingredients, in the manufacture of plasticizers, and as a solvent in specific industrial processes. Its unique branched structure makes it valuable for creating sterically hindered compounds.

How to handle 2,2-dimethylpropan-1-ol safely?

2,2-dimethylpropan-1-ol requires careful handling due to its flammable nature (Flam. Liq. 3) and acute toxicity (Acute Tox. 4). Always wear appropriate personal protective equipment including safety goggles, chemical-resistant gloves, and protective clothing. Work in well-ventilated areas or under fume hoods to avoid inhalation. Keep away from ignition sources, heat, and open flames. Use non-sparking tools and ensure proper grounding of equipment to prevent static electricity buildup.

How to store 2,2-dimethylpropan-1-ol correctly?

2,2-dimethylpropan-1-ol should be stored in a cool, dry, well-ventilated area away from heat sources and ignition points. Use appropriate containers made of compatible materials and ensure they are tightly sealed to prevent evaporation and contamination. Store away from oxidizing agents and strong acids. Maintain storage temperatures below 25°C when possible and implement proper fire prevention measures. Regular inspection of containers for leaks or deterioration is essential for safe storage.

What to do in case of contact with 2,2-dimethylpropan-1-ol?

In case of skin contact with 2,2-dimethylpropan-1-ol, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. If eye contact occurs, rinse immediately with clean water for 15 minutes and seek medical attention. In case of inhalation, move the person to fresh air immediately. If ingested, do not induce vomiting and seek immediate medical attention. Always consult the safety data sheet for complete first aid procedures.

How to dispose of 2,2-dimethylpropan-1-ol appropriately?

2,2-dimethylpropan-1-ol must be disposed of according to local and national hazardous waste regulations. The compound cannot be disposed of through regular waste streams due to its flammable and toxic properties. Contact licensed waste disposal companies for proper treatment, which may include incineration at authorized facilities. Never discharge into sewers, waterways, or soil. Maintain proper documentation of waste disposal activities and ensure compliance with all applicable environmental regulations.

How to transport 2,2-dimethylpropan-1-ol?

2,2-dimethylpropan-1-ol is classified under ADR Class 4.1 (flammable solids), Packing Group II, requiring specific transport regulations compliance. Use approved packaging materials and ensure proper labeling with appropriate hazard symbols and transport documentation. Vehicles must be equipped with suitable fire extinguishing equipment and drivers should hold ADR certification. Avoid transport during extreme weather conditions and ensure proper segregation from incompatible materials during transit. Follow all applicable international transport regulations.

Is 2,2-dimethylpropan-1-ol subject to specific regulations?

2,2-dimethylpropan-1-ol is subject to various chemical regulations including REACH registration requirements in Europe and CLP classification standards. The compound is classified with Warning signal word and requires appropriate GHS labeling (GHS02, GHS07 pictograms). It is not currently listed as an SVHC substance under REACH. Companies must comply with workplace safety regulations, environmental protection laws, and proper notification requirements for manufacturing, import, or use of this chemical substance.

Where to buy 2,2-dimethylpropan-1-ol in Europe?

2,2-dimethylpropan-1-ol is available through OYSI, a trusted European distributor of specialty chemicals. OYSI provides high-quality chemical products with proper documentation, safety data sheets, and regulatory compliance support. As a specialized chemical distributor, OYSI ensures reliable supply chains and technical support for industrial customers across Europe. Contact OYSI directly for product availability, specifications, packaging options, and delivery arrangements to meet your specific industrial or research requirements.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.