2-nitropropane

C3H7NO2

CAS79-46-9
GHS02 Gefahrensymbol: Entzündbar – Flamme
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
Danger

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Identification

CAS Number
79-46-9
EC Number
201-209-1
UN Number
2608
Index Number
609-002-00-1
PubChem CID
398

Physical-chemical properties

Molecular Formula
C3H7NO2
Molar Mass
89.09 g/mol
IUPAC Name
2-nitropropane

Chemical Identifiers

InChI
InChI=1S/C3H7NO2/c1-3(2)4(5)6/h3H,1-2H3
InChI Key
FGLBSLMDCBOPQK-UHFFFAOYSA-N

Overview

2-nitropropane (CAS 79-46-9) is an organic nitroalkane compound characterized by its flammable properties and significant industrial applications as a solvent and chemical intermediate. This colorless liquid represents one of the most commercially important nitroalkane compounds in industrial chemistry. With the molecular formula C3H7NO2 and a molecular weight of 89.09 g/mol, 2-nitropropane serves as a versatile chemical building block in various manufacturing processes. The compound features a nitro group (-NO2) attached to the secondary carbon of a propane chain, giving it unique reactivity patterns that distinguish it from other nitroalkanes and related compounds such as ethylbenzene and styrene used in different industrial applications. The substance exhibits notable flammability characteristics, classified as Flammable Liquid Category 3 under GHS regulations, requiring careful handling and storage protocols. Of particular concern is its classification as a Category 1B carcinogen, necessitating stringent workplace safety measures and personal protective equipment during handling. Additionally, it presents acute toxicity risks, emphasizing the importance of proper ventilation and exposure control in industrial settings. 2-nitropropane finds primary application as a specialty solvent in coatings, inks, and adhesive formulations where its solvating properties and controlled volatility are valued. It also serves as an important intermediate in pharmaceutical synthesis and in the production of certain polymeric materials. The compound's reactivity makes it useful in organic synthesis reactions, particularly in nitroaldol condensations and as a nitrating agent. OYSI maintains reliable supply chains for 2-nitropropane, ensuring consistent availability for European industrial customers requiring this specialized chemical intermediate for their manufacturing processes.

Safety & Classification

Danger
Classification:

Flam. Liq. 3; Carc. 1B; Acute Tox. 4 *; Acute Tox. 4 *

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H226

Flammable liquid and vapour.

H350

May cause cancer.

H332

Harmful if inhaled.

H302

Harmful if swallowed.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Harmful

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2608
ADR Class3
Packing GroupIII
Tunnel CodeD/E
Proper Shipping Name2-Nitropropan
Marine PollutantNo

Frequently Asked Questions

What is 2-nitropropane?

2-nitropropane is an organic nitro compound with the molecular formula C3H7NO2 and CAS number 79-46-9. This chemical substance has a molecular weight of 89.09 g/mol and belongs to the family of secondary nitroalkanes. It is classified as a flammable liquid with carcinogenic properties and acute toxicity. The compound is characterized by a nitro group (-NO2) attached to the central carbon atom of a propane chain, making it a versatile chemical intermediate used in various industrial applications.

What are the physicochemical properties of 2-nitropropane?

2-nitropropane is a colorless to pale yellow liquid at room temperature with a characteristic sweet, fruity odor. It has a boiling point of approximately 120°C and a flash point around 24°C, which contributes to its flammable classification. The compound is moderately soluble in water and miscible with most organic solvents including alcohols and ethers. Its density is approximately 0.99 g/cm³, making it nearly as dense as water. These properties make it suitable for various solvent applications.

What is 2-nitropropane used for?

2-nitropropane serves primarily as a solvent for various industrial applications, particularly in the formulation of inks, paints, adhesives, and synthetic resins. It is used as a chemical intermediate in organic synthesis reactions and as a propellant component in some specialized applications. The compound also finds use in the production of pharmaceuticals and agrochemicals as a building block. Additionally, it serves as a laboratory reagent for analytical and research purposes, though its carcinogenic classification has limited some applications.

How to handle 2-nitropropane safely?

2-nitropropane requires strict safety protocols including wearing appropriate personal protective equipment such as chemical-resistant gloves, safety goggles, and respiratory protection when necessary. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid contact with skin, eyes, and clothing, and eliminate all ignition sources due to its flammable nature. Given its carcinogenic classification (Carc. 1B), minimize exposure time and implement proper hygiene measures including thorough hand washing after handling.

How to store 2-nitropropane correctly?

2-nitropropane must be stored in a cool, dry, well-ventilated area away from heat sources, sparks, and open flames due to its flammable properties. Keep containers tightly sealed and store in original packaging or compatible containers made of suitable materials. The storage area should be equipped with appropriate fire suppression systems and spill containment measures. Keep away from incompatible materials such as strong oxidizers, bases, and reducing agents. Ensure storage areas comply with local fire codes and chemical storage regulations.

What to do in case of contact with 2-nitropropane?

In case of skin contact with 2-nitropropane, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. If eye contact occurs, flush immediately with clean water for at least 15 minutes and seek medical attention. For inhalation exposure, move the person to fresh air and monitor breathing; provide artificial respiration if necessary. If ingested, do not induce vomiting and seek immediate medical attention. Always consult a physician and provide the safety data sheet.

How to dispose of 2-nitropropane appropriately?

2-nitropropane disposal must comply with local, national, and international hazardous waste regulations due to its toxic and carcinogenic properties. The substance should be collected in appropriate containers and disposed of through licensed hazardous waste disposal facilities. Incineration at high temperatures in specialized facilities equipped with appropriate emission controls is typically the preferred disposal method. Empty containers may require special treatment as they retain hazardous residues. Never dispose of this substance through regular waste streams or sewage systems.

How to transport 2-nitropropane?

2-nitropropane is classified under ADR Class 3 (Flammable Liquids), Packing Group III for transportation purposes. It must be transported in approved packaging that meets UN specification requirements and properly labeled with appropriate hazard labels and markings. Vehicles transporting this substance must comply with ADR regulations including proper placarding, driver training, and emergency equipment. Transport documents must accurately describe the substance and its hazards. Ensure compliance with route restrictions and tunnel categories as specified by local transportation authorities.

Is 2-nitropropane subject to specific regulations?

2-nitropropane is subject to comprehensive chemical regulations including REACH registration requirements in Europe and CLP classification for hazard communication. Due to its carcinogenic classification (Category 1B), it falls under strict occupational exposure limits and may be subject to authorization procedures. The substance must be handled according to chemical safety regulations and workplace safety directives. Users must maintain safety data sheets, implement risk management measures, and comply with notification requirements. Regular monitoring and health surveillance may be mandatory in occupational settings.

Where to buy 2-nitropropane in Europe?

2-nitropropane is available through OYSI, a professional European distributor of specialty chemicals serving industrial customers across the continent. As a regulated substance with carcinogenic properties, purchase is typically restricted to qualified industrial users who can demonstrate proper handling capabilities and regulatory compliance. OYSI provides technical support and ensures proper documentation for regulatory requirements. Customers must provide appropriate certifications and intended use information. Contact OYSI directly to discuss availability, specifications, and compliance requirements for your specific application.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.