2-nitro-2-phenylpropane-1,3-diol

2-nitro-2-phenylpropane-1,3-diol is an organic chemical compound with the molecular formula C9H11NO4 and CAS number 5428-02-4. This substance has a molecular weight of 197.19 g/mol and contains both nitro and diol functional groups attached to a phenylpropane backbone. It is classified as a hazardous chemical requiring special handling precautions due to its toxicological properties and environmental impact potential.

2-nitro-2-phenylpropane-1,3-diol is a solid organic compound at room temperature with a molecular weight of 197.19 g/mol. The presence of both hydroxyl groups and the nitro functionality suggests moderate polarity, making it potentially soluble in polar solvents. Its phenyl ring contributes to its aromatic character, while the diol groups provide hydrogen bonding capability, influencing its physical properties and solubility behavior.

2-nitro-2-phenylpropane-1,3-diol is primarily used as a chemical intermediate in pharmaceutical and fine chemical synthesis. Its unique structure, containing both nitro and diol functionalities, makes it valuable for organic synthesis reactions. It may serve as a building block for more complex molecules in medicinal chemistry applications or as a precursor in the manufacture of specialized chemical products requiring its specific functional group combination.

2-nitro-2-phenylpropane-1,3-diol must be handled with appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Work should be conducted in well-ventilated areas or under fume extraction due to its Acute Tox. 4 classification and skin sensitization potential. Avoid direct skin contact and inhalation, as the substance can cause acute toxicity and repeated exposure may lead to organ damage.

2-nitro-2-phenylpropane-1,3-diol should be stored in a cool, dry, well-ventilated area away from incompatible materials. Keep containers tightly sealed and protected from moisture due to its diol functionality. Storage areas should be equipped with appropriate spill containment measures and restricted access due to its hazardous classification. Avoid exposure to heat sources and ensure compatibility with storage container materials.

In case of skin contact with 2-nitro-2-phenylpropane-1,3-diol, immediately remove contaminated clothing and wash affected area thoroughly with soap and water for at least 15 minutes. If inhaled, move to fresh air immediately. In case of eye contact, rinse with clean water for 15 minutes. Seek medical attention if irritation persists or if significant exposure has occurred, especially considering its skin sensitization and acute toxicity properties.

2-nitro-2-phenylpropane-1,3-diol must be disposed of as hazardous waste through licensed waste management companies in accordance with local and European waste regulations. The substance cannot be disposed of in regular waste streams due to its toxicological properties and environmental impact. Contact certified hazardous waste disposal services and provide safety data sheets to ensure proper treatment and disposal methods are employed.

2-nitro-2-phenylpropane-1,3-diol is classified under ADR Class 6.1 (Toxic substances), Packing Group III for transportation. This classification requires appropriate packaging, labeling with proper hazard markings, and transport documentation. Vehicles must comply with ADR regulations for toxic substances, including proper ventilation and emergency equipment. Only authorized carriers experienced in hazardous materials transport should handle shipments of this substance.

2-nitro-2-phenylpropane-1,3-diol is subject to European REACH and CLP regulations due to its hazardous properties. It is classified with multiple hazard classes including acute toxicity, skin sensitization, and specific target organ toxicity. While not currently listed as an SVHC substance, it requires safety data sheets, proper labeling with GHS pictograms (GHS07, GHS08, GHS09), and compliance with occupational exposure limits where applicable.

2-nitro-2-phenylpropane-1,3-diol is available through OYSI, a specialized European distributor of technical chemicals. As an authorized supplier, OYSI can provide this substance with proper documentation, safety data sheets, and regulatory compliance support. Professional customers requiring this chemical intermediate for synthesis or research applications can contact OYSI for availability, specifications, and technical support throughout European markets.