2-nitro-2-phenylpropane-1,3-diol

2-nitro-2-phenylpropane-1,3-diol is an organic chemical compound with the molecular formula C9H11NO4 and CAS number 5428-02-4. This substance features a phenyl ring attached to a propane backbone containing two hydroxyl groups and a nitro group. With a molecular weight of 197.19 g/mol, it belongs to the class of nitro compounds and diols, making it useful in various chemical synthesis applications.

2-nitro-2-phenylpropane-1,3-diol is a solid organic compound at room temperature, typically appearing as a white to off-white crystalline powder. The presence of hydroxyl groups makes it moderately polar, providing some water solubility while the phenyl ring contributes to its organic solvent compatibility. The nitro group influences its chemical reactivity and stability properties, requiring careful handling conditions.

2-nitro-2-phenylpropane-1,3-diol is primarily used as an intermediate in organic synthesis and pharmaceutical manufacturing. Its unique structure with both hydroxyl and nitro functional groups makes it valuable for creating complex molecular frameworks. The compound serves as a building block in the production of specialty chemicals and may be used in research applications for developing new chemical entities.

2-nitro-2-phenylpropane-1,3-diol requires careful handling due to its Acute Tox. 4, STOT RE 1, and Skin Sens. 1 classifications. Essential protective equipment includes chemical-resistant gloves, safety goggles, and appropriate respiratory protection. Work in well-ventilated areas or under fume hoods, avoid skin contact and inhalation, and ensure proper training before handling. Always follow the safety data sheet recommendations and local safety protocols.

2-nitro-2-phenylpropane-1,3-diol should be stored in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Keep containers tightly sealed to prevent moisture absorption and contamination. Store separately from incompatible materials such as strong oxidizers, reducing agents, and bases. Ensure storage areas are equipped with appropriate containment measures and access is restricted to trained personnel only.

Immediate action is required upon contact with 2-nitro-2-phenylpropane-1,3-diol due to its toxic and sensitizing properties. For skin contact, remove contaminated clothing and wash thoroughly with soap and water for at least 15 minutes. If inhaled, move to fresh air immediately. For eye contact, flush with water for 15 minutes. Seek medical attention promptly in all cases and provide the safety data sheet to medical personnel.

2-nitro-2-phenylpropane-1,3-diol must be disposed of according to local and national hazardous waste regulations due to its toxic properties and environmental impact classification (Aquatic Chronic 2). Contact licensed waste disposal companies specializing in chemical waste management. Never dispose of through regular waste streams or pour down drains. Maintain proper documentation of disposal activities and ensure compliance with all applicable environmental regulations.

2-nitro-2-phenylpropane-1,3-diol is classified under ADR Class 6.1 (Toxic substances), Packing Group III for transportation purposes. This classification requires specific packaging standards, labeling with appropriate hazard symbols, and proper shipping documentation. Transportation must comply with ADR regulations for road transport in Europe, including driver training requirements and emergency response procedures. Only use approved packaging and certified transport companies.

2-nitro-2-phenylpropane-1,3-diol is subject to various chemical regulations including REACH registration requirements in Europe and CLP classification obligations. The substance carries GHS pictograms (GHS07, GHS08, GHS09) and requires appropriate safety data sheets. While not currently listed as an SVHC substance, its toxic properties mean it may be subject to workplace exposure limits and environmental monitoring requirements in different jurisdictions.

2-nitro-2-phenylpropane-1,3-diol is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides this compound with proper regulatory compliance, including safety data sheets and transport documentation. As a professional chemical distributor, OYSI ensures quality standards and regulatory compliance for industrial and research applications throughout Europe. Contact OYSI directly for availability, technical specifications, and ordering information.