2-methoxyethyl acetate

C5H10O3

CAS110-49-6
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
Danger

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Identification

CAS Number
110-49-6
EC Number
203-772-9
UN Number
1189
Index Number
607-036-00-1
PubChem CID
8054

Physical-chemical properties

Molecular Formula
C5H10O3
Molar Mass
118.13 g/mol
IUPAC Name
2-methoxyethyl acetate

Chemical Identifiers

InChI
InChI=1S/C5H10O3/c1-5(6)8-4-3-7-2/h3-4H2,1-2H3
InChI Key
XLLIQLLCWZCATF-UHFFFAOYSA-N

Overview

2-methoxyethyl acetate (CAS 110-49-6) is an organic solvent ester with excellent dissolving properties and moderate volatility characteristics. 2-methoxyethyl acetate represents a significant glycol ether acetate widely utilized across various industrial applications due to its exceptional solvency power and controlled evaporation rate. This colorless liquid compound, with the molecular formula C5H10O3 and molecular weight of 118.13 g/mol, exhibits unique chemical properties that make it particularly valuable in specialized coating and chemical formulations. The substance demonstrates superior performance characteristics compared to conventional solvents, offering enhanced compatibility with diverse resin systems and polymer matrices. Its chemical structure combines the benefits of both ether and ester functionalities, resulting in excellent dissolving capabilities for a broad range of organic compounds. Unlike simpler solvents such as ethylbenzene, 2-methoxyethyl acetate provides more controlled evaporation profiles, making it ideal for applications requiring precise drying characteristics. However, this compound requires careful handling protocols due to its classification as Repr. 1B under CLP regulation, indicating potential reproductive toxicity concerns. The GHS08 and GHS07 pictograms reflect both health hazards and acute toxicity risks, necessitating appropriate personal protective equipment and workplace safety measures during industrial use. Primary industrial applications include high-performance coatings, specialty inks, and advanced chemical synthesis processes where superior solvency and controlled volatility are essential. The compound also serves as an intermediate in pharmaceutical manufacturing and specialty chemical production, where its unique properties contribute to improved process efficiency and product quality. OYSI maintains reliable supply chains for 2-methoxyethyl acetate, ensuring consistent availability for European industrial customers requiring this specialized solvent solution.

Safety & Classification

Danger
Classification:

Repr. 1B; Acute Tox. 4 *; Acute Tox. 4 *; Acute Tox. 4 *

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H332

Harmful if inhaled.

H312

Harmful in contact with skin.

H302

Harmful if swallowed.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Harmful

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number1189
ADR Class3
Packing GroupIII
Tunnel CodeD/E
Proper Shipping NameEthylenglycolmonomethyletheracetat
Marine PollutantNo

Frequently Asked Questions

What is 2-methoxyethyl acetate?

2-methoxyethyl acetate is an organic chemical compound with the molecular formula C5H10O3 and CAS number 110-49-6. This acetate ester has a molecular weight of 118.13 g/mol and belongs to the glycol ether acetate family. It is classified as a hazardous substance with reproductive toxicity (Repr. 1B) and acute toxicity properties, requiring careful handling and appropriate safety measures in industrial applications.

What are the physicochemical properties of 2-methoxyethyl acetate?

2-methoxyethyl acetate is typically a colorless liquid at room temperature with a characteristic mild, sweet odor. As an acetate ester, it exhibits moderate volatility and is soluble in many organic solvents. The compound has a relatively low molecular weight of 118.13 g/mol, contributing to its liquid state and moderate vapor pressure under normal conditions.

What is 2-methoxyethyl acetate used for?

2-methoxyethyl acetate is primarily used as a solvent in various industrial applications including coatings, inks, and cleaning formulations. It serves as an effective solvent for resins, lacquers, and other organic materials due to its excellent solvency properties. The compound is also utilized in the production of specialty chemicals and as a processing aid in certain manufacturing operations.

How to handle 2-methoxyethyl acetate safely?

2-methoxyethyl acetate requires strict safety precautions due to its reproductive toxicity and acute toxicity classification. Personnel must wear appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Work should be conducted in well-ventilated areas or under fume extraction systems. Avoid skin contact, inhalation, and ingestion. Pregnant workers should avoid exposure completely due to the Repr. 1B classification.

How to store 2-methoxyethyl acetate correctly?

2-methoxyethyl acetate should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and ignition sources. Storage areas must be equipped with appropriate fire suppression systems due to its flammable nature (ADR Class 3). Keep containers away from incompatible materials such as strong oxidizers and acids. Maintain storage temperature below recommended limits and ensure proper labeling.

What to do in case of contact with 2-methoxyethyl acetate?

In case of skin contact with 2-methoxyethyl acetate, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. If inhaled, move the person to fresh air immediately. For eye contact, rinse thoroughly with clean water for at least 15 minutes. Seek immediate medical attention in all cases of exposure, especially due to the compound's reproductive and acute toxicity properties.

How to dispose of 2-methoxyethyl acetate properly?

2-methoxyethyl acetate must be disposed of as hazardous waste according to local and national regulations. The waste should be collected in appropriate containers and handed over to licensed hazardous waste disposal companies. Incineration at authorized high-temperature facilities is typically the preferred disposal method. Never dispose of this chemical down drains or in regular waste streams due to its toxicity and environmental impact.

How to transport 2-methoxyethyl acetate?

2-methoxyethyl acetate is classified under ADR as Class 3 (flammable liquids), Packing Group III, indicating moderate danger during transport. Transportation must comply with ADR regulations including proper packaging, labeling with appropriate hazard pictogramms (GHS07, GHS08), and documentation. Vehicles must carry appropriate fire extinguishing equipment and drivers require ADR certification for hazardous goods transport.

Is 2-methoxyethyl acetate subject to special regulations?

2-methoxyethyl acetate is subject to multiple regulatory frameworks including REACH registration requirements in Europe and CLP classification as a hazardous substance. The compound carries the signal word 'Danger' and requires specific labeling with GHS pictogramms GHS07 and GHS08. Its Repr. 1B classification means it's subject to restrictions regarding exposure limits and use in consumer products. It is not currently listed as an SVHC substance.

Where to buy 2-methoxyethyl acetate in Europe?

2-methoxyethyl acetate is available through OYSI, a reliable European distributor of technical chemicals. OYSI provides this substance to industrial customers across Europe, ensuring compliance with all relevant safety and regulatory requirements. As a specialized chemical distributor, OYSI offers technical support and proper documentation including safety data sheets and certificates of analysis for professional applications.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.