2-(furan-2-yl)-1H-benzimidazole

2-(furan-2-yl)-1H-benzimidazole is an organic heterocyclic compound with CAS number 3878-19-1 and molecular formula C11H8N2O. This chemical features a benzimidazole ring system fused with a furan moiety, giving it unique structural properties. With a molecular weight of 184.19 g/mol, it belongs to the benzimidazole family of compounds, which are known for their diverse biological and chemical applications in various industrial sectors.

2-(furan-2-yl)-1H-benzimidazole is a solid organic compound at room temperature with the molecular formula C11H8N2O. The compound contains both nitrogen-containing benzimidazole and oxygen-containing furan rings, which influence its solubility characteristics. Its molecular weight is 184.19 g/mol. The specific physical properties such as melting point, color, and solubility parameters depend on purity grade and should be verified through analytical testing for each batch.

2-(furan-2-yl)-1H-benzimidazole is primarily used as an intermediate in pharmaceutical and chemical synthesis applications. The compound serves as a building block for developing more complex molecules due to its reactive benzimidazole and furan functional groups. It may also find applications in research and development activities, particularly in medicinal chemistry and materials science. Its specific heterocyclic structure makes it valuable for creating derivatives with potential biological activity.

2-(furan-2-yl)-1H-benzimidazole requires careful handling due to its classification as Carc. 2, Acute Tox. 4, and Skin Sens. 1. Essential protective equipment includes nitrile gloves, safety goggles, and respiratory protection when handling powders. Work should be conducted in well-ventilated areas or under fume hoods. Avoid skin contact and inhalation, and ensure proper hygiene practices. Emergency eyewash and shower facilities should be readily accessible in work areas where this substance is handled.

2-(furan-2-yl)-1H-benzimidazole should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from incompatible materials. Keep containers away from heat sources, direct sunlight, and moisture to prevent degradation. Storage areas should be clearly labeled and restricted to authorized personnel only. Due to its hazard classification, implement appropriate containment measures and ensure compatibility with storage vessel materials. Regular inventory checks and proper segregation from incompatible chemicals are essential.

Immediate action is required upon contact with 2-(furan-2-yl)-1H-benzimidazole due to its acute toxicity and sensitization potential. For skin contact, immediately remove contaminated clothing and wash affected area thoroughly with soap and water for at least 15 minutes. In case of eye contact, flush with clean water for 15 minutes while holding eyelids open. If inhaled, move to fresh air immediately. Seek immediate medical attention for all exposure routes and provide safety data sheet to medical personnel.

2-(furan-2-yl)-1H-benzimidazole must be disposed of as hazardous waste according to local and national environmental regulations. The substance cannot be discharged into sewers or waterways due to its Aquatic Acute 1 and Chronic 1 classification. Contact licensed hazardous waste disposal companies for proper treatment and disposal. Incineration at authorized facilities with appropriate emission controls is typically required. Always consult current waste disposal regulations and maintain proper documentation for waste tracking.

2-(furan-2-yl)-1H-benzimidazole is classified as ADR Class 9 (Miscellaneous Dangerous Goods), Packing Group III for transportation purposes. This classification requires specific packaging, labeling, and documentation according to dangerous goods regulations. Packages must bear appropriate hazard labels and markings. Transportation should only be conducted by trained personnel with proper dangerous goods certification. Ensure compliance with modal-specific regulations for road, rail, sea, or air transport, and maintain required shipping papers throughout transit.

2-(furan-2-yl)-1H-benzimidazole is subject to REACH regulation for registration, evaluation, and authorization within the EU, though it is not currently listed as a Substance of Very High Concern (SVHC). The compound must comply with CLP regulation for classification, labeling, and packaging as indicated by its hazard classifications. Users must implement appropriate risk management measures and may need to register depending on tonnage thresholds. Always verify current regulatory status before use.

2-(furan-2-yl)-1H-benzimidazole is available through OYSI, a specialized European distributor of chemical products. OYSI provides reliable supply chains for laboratory and industrial customers across Europe, ensuring compliance with all relevant safety and regulatory requirements. As a professional chemical distributor, OYSI can provide proper documentation including safety data sheets, certificates of analysis, and regulatory compliance information. Contact OYSI directly for availability, specifications, and delivery options for your specific requirements.