3-(4-chlorophenyl)-1-methoxy-1-methylurea

C9H11ClN2O2

CAS1746-81-2
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
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Identification

CAS Number
1746-81-2
EC Number
217-129-5
UN Number
3077
Index Number
006-032-00-1
PubChem CID
15629

Physical-chemical properties

Molecular Formula
C9H11ClN2O2
Molar Mass
214.65 g/mol
IUPAC Name
3-(4-chlorophenyl)-1-methoxy-1-methylurea

Chemical Identifiers

InChI
InChI=1S/C9H11ClN2O2/c1-12(14-2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13)
InChI Key
LKJPSUCKSLORMF-UHFFFAOYSA-N

Overview

3-(4-chlorophenyl)-1-methoxy-1-methylurea (CAS 1746-81-2) is a substituted urea compound with selective herbicidal properties and aquatic toxicity concerns. This organochlorine derivative belongs to the phenylurea family of herbicides, characterized by its distinctive chemical structure featuring a 4-chlorophenyl group attached to a methoxy-methylated urea moiety. With the molecular formula C9H11ClN2O2 and a molecular weight of 214.65 g/mol, this compound demonstrates moderate acute toxicity and potential for repeated exposure effects, classified under GHS hazard categories including Acute Tox. 4 and STOT RE 2. The substance exhibits significant environmental persistence and bioaccumulation potential, reflected in its Aquatic Acute 1 and Aquatic Chronic 1 classifications. Safety handling requires adherence to Class 9 ADR transport regulations and implementation of appropriate protective measures due to its Warning signal word designation. The compound's hazard profile, indicated by GHS07, GHS08, and GHS09 pictograms, necessitates careful consideration of both human health and environmental protection protocols. Primary industrial applications include selective weed control in agricultural settings, particularly for pre-emergence and early post-emergence treatments in crop protection programs. The compound also finds utility in vegetation management for industrial sites and specialized turf management applications. While structurally distinct from compounds like 6-amino-N-methylnaphthalene-2-sulfonamide, it shares certain application domains in agricultural chemistry, though with different mechanisms of action and environmental profiles. OYSI maintains reliable supply chains for 3-(4-chlorophenyl)-1-methoxy-1-methylurea, supporting European customers with comprehensive technical documentation and regulatory compliance support for this specialized chemical intermediate.

Safety & Classification

Warning
Classification:

Acute Tox. 4 *; STOT RE 2 *; Aquatic Acute 1; Aquatic Chronic 1

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H302

Harmful if swallowed.

H373

May cause damage to organs through prolonged or repeated exposure.

H400

Very toxic to aquatic life.

H410

Very toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number3077
ADR Class9
Packing GroupIII
Tunnel Code-
Proper Shipping NameMonolinuron (ISO)
Marine PollutantNo

Frequently Asked Questions

What is 3-(4-chlorophenyl)-1-methoxy-1-methylurea?

3-(4-chlorophenyl)-1-methoxy-1-methylurea is an organic chemical compound with the molecular formula C9H11ClN2O2 and CAS number 1746-81-2. This substituted urea derivative contains a chlorinated phenyl ring and methoxy group, giving it a molecular weight of 214.65 g/mol. It is classified as a hazardous substance requiring careful handling due to its acute toxicity and potential for organ damage.

What are the physicochemical properties of 3-(4-chlorophenyl)-1-methoxy-1-methylurea?

3-(4-chlorophenyl)-1-methoxy-1-methylurea is a solid compound at room temperature with a molecular weight of 214.65 g/mol. The presence of the chlorophenyl group and urea backbone influences its polarity and solubility characteristics. Specific physical properties such as melting point, boiling point, and detailed solubility data should be obtained from the safety data sheet for precise handling requirements.

What is 3-(4-chlorophenyl)-1-methoxy-1-methylurea used for?

3-(4-chlorophenyl)-1-methoxy-1-methylurea is primarily used as an intermediate in pharmaceutical synthesis and chemical research applications. Its substituted urea structure makes it valuable for developing bioactive compounds and agrochemicals. The compound serves as a building block in organic synthesis, particularly in medicinal chemistry where chlorinated aromatic compounds are required for specific biological activities.

How to handle 3-(4-chlorophenyl)-1-methoxy-1-methylurea safely?

3-(4-chlorophenyl)-1-methoxy-1-methylurea requires careful handling due to its Acute Tox. 4 and STOT RE 2 classifications. Essential protective equipment includes chemical-resistant gloves, safety goggles, and appropriate respiratory protection in poorly ventilated areas. Work should be conducted in well-ventilated spaces or under fume hoods. Avoid skin and eye contact, inhalation, and ingestion. Ensure emergency procedures are readily available.

How to store 3-(4-chlorophenyl)-1-methoxy-1-methylurea correctly?

3-(4-chlorophenyl)-1-methoxy-1-methylurea should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Due to its environmental hazard classification (Aquatic Acute 1, Aquatic Chronic 1), prevent release to the environment. Store separately from oxidizing agents and food products. Maintain proper labeling and ensure containers are in good condition to prevent leakage.

What to do in case of contact with 3-(4-chlorophenyl)-1-methoxy-1-methylurea?

Immediate action is required upon contact with 3-(4-chlorophenyl)-1-methoxy-1-methylurea due to its acute toxicity. For skin contact, remove contaminated clothing and wash thoroughly with soap and water. In case of eye contact, rinse immediately with plenty of water for at least 15 minutes. If inhaled, move to fresh air. For ingestion, do not induce vomiting and seek immediate medical attention.

How to dispose of 3-(4-chlorophenyl)-1-methoxy-1-methylurea properly?

3-(4-chlorophenyl)-1-methoxy-1-methylurea must be disposed of through licensed hazardous waste disposal facilities due to its environmental and health hazards. The compound cannot be released into the environment given its aquatic toxicity classification. Disposal must comply with local, national, and EU waste regulations. Contact certified waste management companies for proper collection and treatment of contaminated materials and containers.

How to transport 3-(4-chlorophenyl)-1-methoxy-1-methylurea?

3-(4-chlorophenyl)-1-methoxy-1-methylurea is classified under ADR Class 9 (Miscellaneous dangerous substances), Packing Group III for transportation. This classification requires appropriate packaging, labeling, and documentation according to dangerous goods regulations. Vehicles must carry proper placarding and emergency information. Drivers need ADR certification, and shipments must include transport documents specifying the hazard class and proper shipping name.

Is 3-(4-chlorophenyl)-1-methoxy-1-methylurea subject to specific regulations?

3-(4-chlorophenyl)-1-methoxy-1-methylurea is subject to EU REACH and CLP regulations requiring registration, classification, and appropriate labeling with GHS07, GHS08, and GHS09 pictograms. While not currently listed as an SVHC (Substance of Very High Concern), its hazard classifications mandate compliance with occupational exposure limits and environmental protection measures. Users must maintain safety data sheets and implement risk management measures.

Where to buy 3-(4-chlorophenyl)-1-methoxy-1-methylurea in Europe?

3-(4-chlorophenyl)-1-methoxy-1-methylurea is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides reliable supply of this regulated compound with proper documentation, safety data sheets, and regulatory compliance support. Their European distribution network ensures efficient delivery while maintaining the strict handling and transport requirements necessary for this classified hazardous substance.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.