1,4-dichlorobenzene
C6H4Cl2
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Identification
- CAS Number
- 106-46-7
- EC Number
- 203-400-5
- UN Number
- 3077
- Index Number
- 602-035-00-2
- PubChem CID
- 4685
Physical-chemical properties
- Molecular Formula
- C6H4Cl2
- Molar Mass
- 147.00 g/mol
- IUPAC Name
- 1,4-dichlorobenzene
Chemical Identifiers
- InChI
- InChI=1S/C6H4Cl2/c7-5-1-2-6(8)4-3-5/h1-4H
- InChI Key
- OCJBOOLMMGQPQU-UHFFFAOYSA-N
Overview
1,4-dichlorobenzene (CAS 106-46-7) is an organochlorine compound with distinctive aromatic properties and industrial solvent applications. This symmetrical dichlorobenzene isomer represents one of the most commercially significant chlorinated aromatic compounds in industrial chemistry. As a white crystalline solid at room temperature with a characteristic sweet odor, 1,4-dichlorobenzene demonstrates excellent chemical stability and selective reactivity that makes it valuable across multiple industrial sectors. The compound's molecular structure, featuring two chlorine atoms positioned para to each other on the benzene ring, contributes to its unique physical and chemical properties. From a safety perspective, 1,4-dichlorobenzene requires careful handling protocols due to its classification as a Category 2 carcinogen and eye irritant. The compound also presents significant environmental concerns with its acute and chronic aquatic toxicity classifications, necessitating proper containment and disposal procedures. Its Class 9 ADR classification reflects its miscellaneous dangerous goods status for transportation purposes. Industrial applications of 1,4-dichlorobenzene span several key sectors, primarily as a chemical intermediate in the production of polyphenylene sulfide (PPS) plastics and as a solvent in various manufacturing processes. The compound also serves as a precursor in pharmaceutical synthesis, where it may be used alongside other aromatic compounds such as 6-amino-N-methylnaphthalene-2-sulfonamide in specialized chemical transformations. Additionally, it finds application in the production of dyes, pesticides, and other specialty chemicals where its aromatic chlorinated structure provides essential reactivity. OYSI maintains reliable supply chains for 1,4-dichlorobenzene to support our European industrial customers' technical requirements.
Safety & Classification
Carc. 2; Eye Irrit. 2; Aquatic Acute 1; Aquatic Chronic 1
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Eye Contact
Measures if substance gets into the eyes
First Aid Actions
- +P305IF IN EYES:
- +P351Rinse cautiously with water for several minutes.
- +P338Remove contact lenses, if present and easy to do. Continue rinsing.
- +P313Get medical advice/attention.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 3077 |
| ADR Class | 9 |
| Packing Group | III |
| Tunnel Code | - |
| Proper Shipping Name | 1,4-Dichlorbenzen, fest |
| Marine Pollutant | No |
Frequently Asked Questions
What is 1,4-dichlorobenzene?
1,4-dichlorobenzene is an aromatic organochlorine compound with the molecular formula C6H4Cl2 and CAS number 106-46-7. It consists of a benzene ring with two chlorine atoms positioned at opposite ends (para position). This white crystalline solid has a distinctive sweet odor and a molecular weight of 147 g/mol. It is classified as a potentially carcinogenic substance and poses risks to aquatic environments.
What are the physicochemical properties of 1,4-dichlorobenzene?
1,4-dichlorobenzene is a white crystalline solid at room temperature with a characteristic sweet, mothball-like odor. It has low water solubility but dissolves readily in organic solvents such as alcohol, ether, and benzene. The compound sublimes easily, transitioning directly from solid to vapor phase. It has a melting point of approximately 53°C and boiling point of 174°C, making it volatile under normal conditions.
What is 1,4-dichlorobenzene used for?
1,4-dichlorobenzene is primarily used as an intermediate in chemical synthesis, particularly in the production of pesticides, dyes, and pharmaceuticals. It serves as a precursor for manufacturing other chlorinated aromatic compounds. Historically, it was widely used as a moth repellent and air freshener, though these applications have decreased due to health concerns. Industrial applications include use as a fumigant and in specialized chemical manufacturing processes.
How to handle 1,4-dichlorobenzene safely?
1,4-dichlorobenzene requires careful handling with appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and respiratory protection in poorly ventilated areas. Work should be conducted in well-ventilated spaces or under fume hoods to minimize inhalation exposure. Avoid direct skin and eye contact, as the substance can cause irritation. Ensure no ignition sources are present, and follow proper hygiene practices including thorough handwashing after handling.
How to store 1,4-dichlorobenzene correctly?
1,4-dichlorobenzene should be stored in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Use tightly sealed containers made of compatible materials to prevent sublimation and vapor escape. Store separately from incompatible substances such as strong oxidizing agents and bases. Maintain storage temperatures below 25°C when possible and ensure storage areas are equipped with appropriate spill containment measures and emergency equipment.
What to do in case of contact with 1,4-dichlorobenzene?
In case of skin contact with 1,4-dichlorobenzene, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, rinse immediately with clean water for 15-20 minutes and remove contact lenses if present. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical attention. In all cases of significant exposure, consult a physician promptly.
How to dispose of 1,4-dichlorobenzene properly?
1,4-dichlorobenzene must be disposed of as hazardous waste through licensed waste management companies in compliance with local and European regulations. It cannot be disposed of in regular municipal waste or poured down drains due to its environmental persistence and toxicity. Incineration at high temperatures in authorized facilities is typically the preferred disposal method. Always consult with certified waste disposal specialists and maintain proper documentation for regulatory compliance.
How to transport 1,4-dichlorobenzene?
1,4-dichlorobenzene is classified as ADR Class 9 (miscellaneous dangerous substances), Packing Group III for transportation purposes. It requires appropriate hazardous goods documentation, labeling with GHS08, GHS07, and GHS09 pictograms, and packaging in UN-approved containers. Vehicles must carry emergency response information and drivers need ADR certification. Transport should follow the European Agreement concerning the International Carriage of Dangerous Goods by Road regulations.
Is 1,4-dichlorobenzene subject to specific regulations?
1,4-dichlorobenzene is subject to comprehensive European chemical regulations including REACH registration requirements and CLP classification as Carcinogenic Category 2, Eye Irritant Category 2, and Aquatic Acute/Chronic Category 1. It requires safety data sheets and appropriate hazard labeling with warning signal word. While not currently listed as an SVHC, its carcinogenic classification means it faces restrictions in consumer applications and requires careful occupational exposure management under workplace safety directives.
Where to buy 1,4-dichlorobenzene in Europe?
1,4-dichlorobenzene is available through OYSI, a specialized European distributor of technical chemicals. As an established supplier, OYSI provides this compound to industrial and research customers across Europe, ensuring full regulatory compliance and proper documentation. Professional chemical distributors like OYSI offer technical support, appropriate packaging, and safety documentation required for industrial applications. Contact specialized chemical suppliers for specific quantities, specifications, and delivery arrangements.
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Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.