1,4-dichlorobenzene

C6H4Cl2

CAS106-46-7
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
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Identification

CAS Number
106-46-7
EC Number
203-400-5
UN Number
3077
Index Number
602-035-00-2
PubChem CID
4685

Physical-chemical properties

Molecular Formula
C6H4Cl2
Molar Mass
147.00 g/mol
IUPAC Name
1,4-dichlorobenzene

Chemical Identifiers

InChI
InChI=1S/C6H4Cl2/c7-5-1-2-6(8)4-3-5/h1-4H
InChI Key
OCJBOOLMMGQPQU-UHFFFAOYSA-N

Overview

1,4-dichlorobenzene (CAS 106-46-7) is an aromatic organochlorine compound with strong chemical stability and distinctive odor properties. This chlorinated benzene derivative, also known as para-dichlorobenzene, represents one of the most commercially significant isomers in the dichlorobenzene family. With its molecular formula C6H4Cl2 and molecular weight of 147 g/mol, this crystalline solid exhibits excellent thermal stability and low water solubility, making it valuable across multiple industrial applications. The compound's symmetrical structure, where two chlorine atoms occupy opposite positions on the benzene ring, contributes to its unique physical and chemical characteristics. From a safety perspective, 1,4-dichlorobenzene requires careful handling due to its classification as a potential carcinogen (Carc. 2) and eye irritant (Eye Irrit. 2). The substance also presents significant environmental concerns, classified as acutely and chronically toxic to aquatic life (Aquatic Acute 1; Aquatic Chronic 1). These hazard classifications necessitate appropriate personal protective equipment and environmental containment measures during handling and storage. Industrial applications primarily include its use as a chemical intermediate in polymer production, particularly in the manufacture of polyphenylene sulfide resins and engineering plastics. The compound also serves as a precursor for agricultural chemicals and specialty chemicals synthesis. While structurally different from complex molecules like 1-(4-chlorophenyl)-4,4-dimethyl-3-(1,2,4-triazol-1-ylmethyl)pentan-3-ol, both compounds demonstrate the versatility of chlorinated aromatics in industrial chemistry. Transportation regulations classify 1,4-dichlorobenzene under ADR Class 9, reflecting its miscellaneous dangerous goods status. OYSI maintains reliable supply chains for this essential industrial chemical, ensuring consistent availability for European customers requiring high-purity dichlorobenzene for their manufacturing processes.

Safety & Classification

Warning
Classification:

Carc. 2; Eye Irrit. 2; Aquatic Acute 1; Aquatic Chronic 1

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H351

Suspected of causing cancer.

H319

Causes serious eye irritation.

H400

Very toxic to aquatic life.

H410

Very toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Eye Contact

Irritant

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number3077
ADR Class9
Packing GroupIII
Tunnel Code-
Proper Shipping Name1,4-Dichlorbenzen, fest
Marine PollutantNo

Frequently Asked Questions

What is 1,4-dichlorobenzene?

1,4-dichlorobenzene is an aromatic organochlorine compound with the molecular formula C6H4Cl2 and CAS number 106-46-7. It consists of a benzene ring with two chlorine atoms positioned at opposite ends (para-position). This white crystalline solid has a distinctive sweet odor and a molecular weight of 147 g/mol. It is classified as a Category 2 carcinogen and poses risks to aquatic environments.

What are the physicochemical properties of 1,4-dichlorobenzene?

1,4-dichlorobenzene is a white crystalline solid at room temperature with a characteristic sweet, mothball-like odor. It has a melting point of 53°C and boiling point of 174°C. The compound is poorly soluble in water but readily dissolves in organic solvents such as alcohol, ether, and benzene. It has a density of 1.458 g/cm³ and exhibits volatility at ambient temperatures.

What is 1,4-dichlorobenzene used for?

1,4-dichlorobenzene is primarily used as a chemical intermediate in the production of polyphenylene sulfide resins and other specialty polymers. It serves as a precursor for pharmaceuticals, agrochemicals, and dyes. The compound is also utilized as a fumigant and moth repellent, though these applications are increasingly restricted due to health concerns. Industrial applications include its use as a process solvent and deodorizer.

How to handle 1,4-dichlorobenzene safely?

1,4-dichlorobenzene requires careful handling with appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and respiratory protection when ventilation is inadequate. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation. Avoid skin and eye contact, and prevent ingestion. Use non-sparking tools and ensure proper grounding to prevent static electricity buildup during handling operations.

How to store 1,4-dichlorobenzene correctly?

1,4-dichlorobenzene should be stored in a cool, dry, well-ventilated area away from heat sources, ignition sources, and direct sunlight. Keep containers tightly sealed to prevent vapor release and contamination. Store away from strong oxidizing agents, acids, and bases. Maintain storage temperatures below 25°C and ensure adequate separation from incompatible materials. Use appropriate containment measures to prevent environmental release.

What to do in case of contact with 1,4-dichlorobenzene?

In case of skin contact with 1,4-dichlorobenzene, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, flush immediately with clean water for 15 minutes while keeping eyelids open. If inhaled, move to fresh air immediately. In case of ingestion, do not induce vomiting and seek immediate medical attention, providing the safety data sheet to medical personnel.

How to dispose of 1,4-dichlorobenzene properly?

1,4-dichlorobenzene must be disposed of as hazardous waste through licensed waste management companies in accordance with local, national, and EU regulations. The substance cannot be disposed of in regular waste streams or sewage systems due to its environmental hazard classification. Incineration at authorized high-temperature facilities is typically the preferred disposal method. Always consult local environmental authorities for specific disposal requirements and approved disposal facilities.

How to transport 1,4-dichlorobenzene?

1,4-dichlorobenzene is classified as ADR Class 9 (Miscellaneous dangerous substances), Packing Group III for transportation purposes. It requires proper packaging in UN-approved containers with appropriate labeling including the Class 9 hazard label. Transport vehicles must carry proper documentation and emergency response information. Drivers require ADR training for Class 9 substances, and specific routing and parking restrictions may apply depending on local regulations.

Is 1,4-dichlorobenzene subject to specific regulations?

1,4-dichlorobenzene is subject to comprehensive EU regulations including REACH registration requirements and CLP classification as Carcinogenic Category 2, Eye Irritant 2, and Aquatic hazard. It may be subject to restrictions under REACH Annex XVII depending on intended use. The substance requires safety data sheets and appropriate hazard communication. Users must comply with occupational exposure limits and environmental discharge restrictions established by member states.

Where to buy 1,4-dichlorobenzene in Europe?

1,4-dichlorobenzene is available through OYSI, a European distributor of specialty chemicals serving industrial customers across Europe. OYSI provides technical-grade 1,4-dichlorobenzene with full regulatory compliance including REACH registration, safety data sheets, and proper packaging. As an established chemical distributor, OYSI ensures reliable supply chains and technical support for industrial applications requiring this specialized aromatic compound.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.