2-amino-3-chloronaphthalene-1,4-dione

2-amino-3-chloronaphthalene-1,4-dione is an organic chemical compound with the molecular formula C10H6ClNO2 and CAS number 2797-51-5. This substituted naphthoquinone derivative features both amino and chlorine functional groups on a naphthalene-1,4-dione backbone. With a molecular weight of 207.61 g/mol, it belongs to the quinone family of compounds and exhibits significant hazardous properties requiring careful handling and storage protocols.

2-amino-3-chloronaphthalene-1,4-dione is a solid organic compound at room temperature with a molecular weight of 207.61 g/mol. As a naphthoquinone derivative, it typically appears as a colored crystalline solid, though specific color and odor characteristics depend on purity and crystal form. The presence of both polar amino groups and nonpolar aromatic structures affects its solubility profile in various solvents.

2-amino-3-chloronaphthalene-1,4-dione serves as an important intermediate in organic synthesis and pharmaceutical research. This compound is primarily utilized in the manufacture of dyes, pigments, and pharmaceutical intermediates due to its reactive quinone structure. Its amino and chlorine substituents make it valuable for further chemical modifications in drug discovery and specialty chemical production processes requiring specific functional group combinations.

2-amino-3-chloronaphthalene-1,4-dione requires careful handling due to its classification as Carc. 2, Repr. 2, and Skin Sens. 1A. Essential personal protective equipment includes nitrile gloves, safety goggles, and respiratory protection to prevent inhalation. Work in well-ventilated areas or under fume hoods, avoid skin contact and dust generation. Regular health monitoring is recommended due to potential carcinogenic and reproductive toxicity concerns.

2-amino-3-chloronaphthalene-1,4-dione should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Keep separated from incompatible materials such as strong oxidizers and reducing agents. Storage areas must be clearly labeled with appropriate hazard warnings and equipped with emergency response equipment. Maintain inventory records and regularly inspect containers for integrity.

Immediate action is required upon contact with 2-amino-3-chloronaphthalene-1,4-dione. For skin contact, remove contaminated clothing and wash affected area thoroughly with soap and water for at least 15 minutes. In case of eye contact, rinse immediately with clean water for 15 minutes and seek medical attention. If inhaled, move to fresh air immediately. Always consult a physician and provide the safety data sheet.

2-amino-3-chloronaphthalene-1,4-dione must be disposed of as hazardous waste according to local and European regulations. Contact licensed hazardous waste disposal companies for proper handling and incineration at authorized facilities. Never dispose of this material in regular waste streams, sewers, or the environment due to its carcinogenic properties and environmental hazard classification (Aquatic Acute 1). Maintain disposal documentation for regulatory compliance.

2-amino-3-chloronaphthalene-1,4-dione is classified as ADR Class 9 (Miscellaneous dangerous goods), Packing Group III for transportation purposes. Packages must be properly labeled with appropriate hazard markings and accompanied by transport documentation. Use UN-specification packaging suitable for solid hazardous materials. Drivers require ADR training certification, and vehicles must carry appropriate emergency equipment and placarding according to European transport regulations.

2-amino-3-chloronaphthalene-1,4-dione is subject to comprehensive European chemical regulations including REACH registration requirements and CLP classification obligations. While not currently listed as a SVHC (Substance of Very High Concern), its carcinogenic and reproductive toxicity classifications require strict compliance with occupational exposure limits and worker protection measures. Importers and users must maintain safety data sheets and implement appropriate risk management measures.

2-amino-3-chloronaphthalene-1,4-dione is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides this compound to qualified industrial and research customers with proper handling capabilities and regulatory compliance. As a controlled substance requiring specialized handling, purchases are subject to customer qualification procedures and appropriate documentation. Contact OYSI directly for availability, specifications, and technical support services.