2-fluoroacetic acid

2-fluoroacetic acid is an organofluorine compound with the molecular formula C2H3FO2 and CAS number 144-49-0. This chemical substance has a molecular weight of 78.04 g/mol and belongs to the class of halogenated carboxylic acids. It is classified as highly toxic (Acute Tox. 2) and poses significant environmental hazards to aquatic life. The compound requires careful handling due to its dangerous properties and is regulated under various safety protocols.

2-fluoroacetic acid is typically a colorless to pale yellow liquid or crystalline solid at room temperature. The compound is highly soluble in water and polar solvents due to its carboxylic acid functional group. It exhibits typical carboxylic acid behavior with a characteristic acidic odor. The presence of the fluorine atom significantly affects its chemical reactivity and biological activity compared to acetic acid, making it considerably more toxic and persistent.

2-fluoroacetic acid is primarily used as a research chemical and intermediate in organic synthesis. It serves as a building block for producing fluorinated pharmaceuticals, agrochemicals, and specialty chemicals. The compound is also utilized in biochemical research as a metabolic inhibitor and in studies involving fluorine chemistry. Due to its high toxicity, its applications are strictly limited to professional and industrial settings with appropriate safety measures and regulatory compliance.

2-fluoroacetic acid requires extreme caution during handling due to its Acute Tox. 2 classification. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and protective clothing. Work must be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid skin contact and ingestion at all costs. Only trained personnel should handle this substance, following strict laboratory protocols and emergency procedures for hazardous chemicals.

2-fluoroacetic acid must be stored in tightly sealed, chemically compatible containers in a cool, dry, well-ventilated area. Keep away from heat sources, direct sunlight, and incompatible materials such as strong bases and oxidizing agents. Storage areas should be equipped with appropriate containment systems and restricted access. Due to its high toxicity and environmental hazards, implement secondary containment measures and ensure proper labeling with GHS06 and GHS09 pictograms.

Immediate medical attention is critical for any exposure to 2-fluoroacetic acid due to its high toxicity. For skin contact, remove contaminated clothing and rinse affected area with copious amounts of water for at least 15 minutes. In case of eye contact, flush immediately with water and seek emergency medical care. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and contact poison control or emergency services immediately.

2-fluoroacetic acid disposal must comply with local and international hazardous waste regulations due to its toxic and environmentally hazardous classification. The substance cannot be disposed of through regular waste streams and requires specialized hazardous waste treatment facilities. Contact certified waste disposal companies experienced in handling toxic chemicals. Neutralization should only be performed by qualified professionals following approved procedures. Documentation of proper disposal is essential for regulatory compliance.

2-fluoroacetic acid is classified under ADR Class 6.1 (Toxic substances), Packing Group I, indicating the highest level of toxicity for transport purposes. Transportation requires specialized packaging meeting UN specifications and proper hazard labeling with toxic substance markings. Only authorized carriers trained in dangerous goods transport can handle shipments. Documentation must include safety data sheets and emergency response information. Air transport may have additional restrictions due to the substance's toxicity classification.

2-fluoroacetic acid is subject to strict regulations under multiple frameworks including REACH, CLP, and national chemical safety laws. While not currently listed as an SVHC, its Acute Tox. 2 and environmental hazard classifications require compliance with hazardous substance regulations. Import/export may require permits or notifications depending on jurisdiction. Users must maintain safety data sheets, implement risk assessments, and follow occupational exposure limits where established.

2-fluoroacetic acid is available through OYSI, a European distributor of chemical products specializing in technical chemicals. As an established supplier, OYSI can provide this regulated substance to qualified customers with appropriate permits and safety protocols. Due to the compound's high toxicity and regulatory requirements, purchases are restricted to professional users with demonstrated need and proper handling capabilities. Contact OYSI directly for availability, technical specifications, and regulatory compliance support.