2-chloro-6-nitro-3-phenoxyaniline

2-chloro-6-nitro-3-phenoxyaniline is an organic compound with the molecular formula C12H9ClN2O3 and CAS number 74070-46-5. This aromatic amine derivative contains chloro, nitro, and phenoxy functional groups attached to an aniline core structure. With a molecular weight of 264.66 g/mol, it is classified as a hazardous substance requiring careful handling due to its carcinogenic potential and environmental toxicity.

2-chloro-6-nitro-3-phenoxyaniline is typically a solid crystalline compound at room temperature with a molecular weight of 264.66 g/mol. The presence of multiple functional groups (chloro, nitro, phenoxy) influences its solubility characteristics and stability. As an aromatic amine derivative, it exhibits typical properties of substituted anilines, though specific physical parameters like melting point and solubility require detailed technical documentation for precise values.

2-chloro-6-nitro-3-phenoxyaniline is primarily used as an intermediate in organic synthesis and pharmaceutical manufacturing. Its complex aromatic structure with multiple reactive sites makes it valuable for developing specialized chemicals, dyes, and potentially pharmaceutical compounds. The compound serves as a building block in chemical research and industrial applications where specific substitution patterns on aniline derivatives are required for targeted synthetic pathways.

2-chloro-6-nitro-3-phenoxyaniline requires strict safety measures due to its carcinogenic classification (Carc. 2) and skin sensitizing properties (Skin Sens. 1A). Essential protective equipment includes chemical-resistant gloves, safety goggles, and respiratory protection in well-ventilated areas. Avoid direct skin contact and inhalation. Work in fume hoods when possible, wear appropriate protective clothing, and ensure emergency washing facilities are readily available during handling operations.

2-chloro-6-nitro-3-phenoxyaniline should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Keep containers in secondary containment to prevent environmental release, given its aquatic toxicity classification. Store separately from strong oxidizers, reducing agents, and food products. Maintain proper labeling with GHS pictograms (GHS07, GHS08, GHS09) and ensure access is restricted to trained personnel only.

Immediate action is required upon contact with 2-chloro-6-nitro-3-phenoxyaniline due to its skin sensitizing properties. For skin contact, remove contaminated clothing and wash affected area thoroughly with soap and water for at least 15 minutes. In case of eye contact, flush with clean water for 15 minutes. If inhaled, move to fresh air immediately. Seek medical attention promptly for any exposure, especially considering the compound's carcinogenic classification.

2-chloro-6-nitro-3-phenoxyaniline disposal must comply with local and European waste regulations due to its hazardous classification. The compound requires disposal as hazardous waste through authorized waste management companies capable of handling carcinogenic and environmentally toxic substances. Never discharge into sewers or the environment given its aquatic toxicity classification. Consult local authorities for specific disposal codes and approved treatment facilities for safe destruction or treatment.

2-chloro-6-nitro-3-phenoxyaniline is classified as ADR Class 9 (miscellaneous dangerous goods), Packing Group III for transportation purposes. This classification requires appropriate packaging, labeling, and documentation according to dangerous goods regulations. Shipments must include proper shipping papers, emergency response information, and comply with quantity limitations for different transport modes. Use UN-approved packaging and ensure drivers have appropriate dangerous goods training certification.

2-chloro-6-nitro-3-phenoxyaniline is subject to multiple European regulations including REACH registration requirements and CLP classification as Carc. 2, Skin Sens. 1A, and environmentally hazardous. While not currently listed as an SVHC, its carcinogenic classification means it may face future regulatory scrutiny. Users must comply with occupational exposure limits, waste disposal regulations, and may require authorization for certain uses under chemical safety legislation.

2-chloro-6-nitro-3-phenoxyaniline is available through OYSI, a specialized European distributor of technical chemicals. As an established chemical supplier, OYSI provides this compound to qualified industrial customers with appropriate handling capabilities and regulatory compliance. Given the substance's hazardous classification, purchases typically require verification of proper storage facilities, safety training, and intended use documentation to ensure responsible distribution and handling throughout the supply chain.