2-chloro-N-(2,6-dimethylphenyl)-N-(pyrazol-1-ylmethyl)acetamide

C14H16ClN3O

CAS67129-08-2
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
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Identification

CAS Number
67129-08-2
EC Number
266-583-0
UN Number
3077
Index Number
616-205-00-9
PubChem CID
49384

Physical-chemical properties

Molecular Formula
C14H16ClN3O
Molar Mass
277.75 g/mol
IUPAC Name
2-chloro-N-(2,6-dimethylphenyl)-N-(pyrazol-1-ylmethyl)acetamide

Chemical Identifiers

InChI
InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3
InChI Key
STEPQTYSZVCJPV-UHFFFAOYSA-N

Overview

2-chloro-N-(2,6-dimethylphenyl)-N-(pyrazol-1-ylmethyl)acetamide (CAS 67129-08-2) is a chlorinated organic compound with fungicidal properties and significant environmental persistence. This specialized chemical compound, with molecular formula C14H16ClN3O and molecular weight 277.75 g/mol, belongs to the class of acetamide derivatives featuring both aromatic and heterocyclic structural elements. The presence of the pyrazole ring system and dimethylphenyl group contributes to its distinctive chemical behavior and biological activity profile. The compound presents notable safety considerations, classified as a Category 2 carcinogen and Category 1B skin sensitizer according to GHS classification. Its environmental impact profile is particularly significant, with Aquatic Acute 1 and Aquatic Chronic 1 classifications indicating high toxicity to aquatic organisms and long-term environmental persistence. These characteristics require careful handling protocols and appropriate waste management procedures during industrial applications. From a regulatory perspective, the substance falls under ADR Class 9 for transport purposes, reflecting its miscellaneous dangerous goods classification. The assigned GHS pictograms (GHS08, GHS07, GHS09) emphasize health hazards, including carcinogenic potential, and environmental dangers that must be communicated throughout the supply chain. Industrial applications primarily center around agricultural formulations and specialized chemical synthesis processes. The compound's structural similarity to other biologically active molecules, such as certain sulfonamide derivatives, makes it valuable in pharmaceutical intermediate synthesis and crop protection research. Unlike simpler aromatic compounds such as 1,4-dichlorobenzene, this acetamide derivative offers more targeted biological activity profiles. OYSI provides reliable access to 2-chloro-N-(2,6-dimethylphenyl)-N-(pyrazol-1-ylmethyl)acetamide with comprehensive safety documentation and regulatory compliance support for European industrial customers.

Safety & Classification

Warning
Classification:

Carc. 2; Skin Sens. 1B; Aquatic Acute 1; Aquatic Chronic 1

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H351

Suspected of causing cancer.

H317

May cause an allergic skin reaction.

H400

Very toxic to aquatic life.

H410

Very toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Skin Contact

Irritant

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number3077
ADR Class9
Packing GroupIII
Tunnel Code-
Proper Shipping NameMetazachlor (ISO)
Marine PollutantNo

Frequently Asked Questions

What is 2-chloro-N-(2,6-dimethylphenyl)-N-(pyrazol-1-ylmethyl)acetamide?

2-chloro-N-(2,6-dimethylphenyl)-N-(pyrazol-1-ylmethyl)acetamide is an organic chemical compound with CAS number 67129-08-2 and molecular formula C14H16ClN3O. This acetamide derivative has a molecular weight of 277.75 g/mol and contains chlorine, nitrogen, and oxygen functional groups. It is classified as a hazardous substance with carcinogenic potential and environmental toxicity concerns, requiring careful handling in professional applications.

What are the physicochemical properties of 2-chloro-N-(2,6-dimethylphenyl)-N-(pyrazol-1-ylmethyl)acetamide?

2-chloro-N-(2,6-dimethylphenyl)-N-(pyrazol-1-ylmethyl)acetamide is a solid organic compound at room temperature with a molecular weight of 277.75 g/mol. The compound contains aromatic rings, chloro, and amide functional groups that influence its physical properties. Specific data on color, odor, melting point, and solubility characteristics should be obtained from the safety data sheet for precise handling and application requirements.

What is 2-chloro-N-(2,6-dimethylphenyl)-N-(pyrazol-1-ylmethyl)acetamide used for?

2-chloro-N-(2,6-dimethylphenyl)-N-(pyrazol-1-ylmethyl)acetamide is primarily used as an intermediate in organic synthesis and pharmaceutical research applications. Its unique chemical structure makes it valuable for developing specialized compounds in industrial chemistry. The substance may also serve as a building block for agrochemical formulations or other specialty chemical products requiring specific molecular configurations with chlorinated acetamide functionality.

How to handle 2-chloro-N-(2,6-dimethylphenyl)-N-(pyrazol-1-ylmethyl)acetamide safely?

2-chloro-N-(2,6-dimethylphenyl)-N-(pyrazol-1-ylmethyl)acetamide requires careful handling due to its carcinogenic potential and skin sensitizing properties. Personnel must wear appropriate personal protective equipment including nitrile gloves, safety goggles, and lab coats. Work in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid skin contact and implement proper hygiene procedures. Handle only in designated areas with appropriate emergency equipment readily available.

How to store 2-chloro-N-(2,6-dimethylphenyl)-N-(pyrazol-1-ylmethyl)acetamide correctly?

2-chloro-N-(2,6-dimethylphenyl)-N-(pyrazol-1-ylmethyl)acetamide should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Keep containers properly labeled and segregated from food, beverages, and animal feed. Storage areas must be secure with restricted access due to the substance's hazardous properties. Regular inspection of containers for damage or leaks is essential for safe storage practices.

What to do in case of contact with 2-chloro-N-(2,6-dimethylphenyl)-N-(pyrazol-1-ylmethyl)acetamide?

Immediate action is required if contact occurs with 2-chloro-N-(2,6-dimethylphenyl)-N-(pyrazol-1-ylmethyl)acetamide. For skin contact, remove contaminated clothing and wash affected area thoroughly with soap and water for at least 15 minutes. In case of eye contact, rinse immediately with clean water for 15 minutes. If inhaled, move to fresh air immediately. Seek medical attention promptly for any exposure, especially considering the substance's carcinogenic and sensitizing properties.

How to dispose of 2-chloro-N-(2,6-dimethylphenyl)-N-(pyrazol-1-ylmethyl)acetamide appropriately?

2-chloro-N-(2,6-dimethylphenyl)-N-(pyrazol-1-ylmethyl)acetamide must be disposed of as hazardous waste through licensed waste management companies. The substance cannot be disposed of in regular waste streams due to its carcinogenic classification and environmental toxicity. Disposal methods should comply with local, national, and EU regulations including the Waste Framework Directive. Contact specialized waste disposal services for proper collection, treatment, and destruction of this regulated chemical compound.

How to transport 2-chloro-N-(2,6-dimethylphenyl)-N-(pyrazol-1-ylmethyl)acetamide?

2-chloro-N-(2,6-dimethylphenyl)-N-(pyrazol-1-ylmethyl)acetamide is classified as ADR Class 9 (Miscellaneous dangerous goods), Packing Group III for transportation purposes. This classification requires appropriate packaging, labeling, and documentation according to international dangerous goods regulations. Shipments must include proper shipping names, hazard labels, and safety data sheets. Only qualified carriers experienced in handling hazardous materials should transport this substance to ensure regulatory compliance and safety.

Is 2-chloro-N-(2,6-dimethylphenyl)-N-(pyrazol-1-ylmethyl)acetamide subject to special regulations?

2-chloro-N-(2,6-dimethylphenyl)-N-(pyrazol-1-ylmethyl)acetamide is subject to multiple regulatory frameworks including REACH registration requirements and CLP classification as Carcinogen Category 2 and Skin Sensitizer 1B. The substance requires safety data sheets and appropriate hazard communication. While not currently listed as an SVHC, its hazardous properties mandate compliance with occupational safety regulations and environmental protection measures throughout the European Union.

Where to buy 2-chloro-N-(2,6-dimethylphenyl)-N-(pyrazol-1-ylmethyl)acetamide in Europe?

2-chloro-N-(2,6-dimethylphenyl)-N-(pyrazol-1-ylmethyl)acetamide is available through OYSI, a European distributor specializing in technical chemicals and intermediates. OYSI provides comprehensive support including regulatory documentation, safety data sheets, and technical guidance for professional customers. As a specialized chemical compound, availability may be subject to minimum order quantities and lead times. Contact OYSI directly for current availability, specifications, and compliance documentation for your specific application requirements.

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Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.