1-[(2,4-dichlorophenyl)carbamoyl]cyclopropane-1-carboxylic acid

1-[(2,4-dichlorophenyl)carbamoyl]cyclopropane-1-carboxylic acid is a synthetic organic compound with the molecular formula C11H9Cl2NO3 and CAS number 113136-77-9. This chemical features a cyclopropane ring substituted with a carboxylic acid group and a carbamoyl group linked to a dichlorophenyl moiety. With a molecular weight of 274.1 g/mol, it belongs to the class of substituted carboxylic acids and exhibits moderate toxicity properties requiring careful handling protocols.

1-[(2,4-dichlorophenyl)carbamoyl]cyclopropane-1-carboxylic acid is a solid compound at room temperature with a molecular weight of 274.1 g/mol. The presence of both hydrophilic carboxylic acid and hydrophobic dichlorophenyl groups suggests moderate polarity. The cyclopropane ring structure provides rigidity to the molecule, while the carbamoyl linkage offers hydrogen bonding capabilities. Specific physical properties like melting point, solubility, and appearance may vary depending on purity and crystalline form.

1-[(2,4-dichlorophenyl)carbamoyl]cyclopropane-1-carboxylic acid is primarily used as an intermediate in pharmaceutical and agrochemical synthesis. Its unique structural features, including the cyclopropane ring and dichlorophenyl carbamoyl functionality, make it valuable for developing bioactive compounds. The compound may serve in research applications for drug discovery, particularly in developing molecules targeting specific biological pathways. Industrial applications typically involve its use as a building block in multi-step synthetic processes.

1-[(2,4-dichlorophenyl)carbamoyl]cyclopropane-1-carboxylic acid requires careful handling due to its Acute Tox. 4 classification. Essential protective equipment includes nitrile gloves, safety goggles, and laboratory coats. Work in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid skin and eye contact, and never ingest the material. Use appropriate handling tools and ensure proper training before use. Keep emergency eyewash stations and safety showers accessible when working with this compound.

1-[(2,4-dichlorophenyl)carbamoyl]cyclopropane-1-carboxylic acid should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Keep containers upright and properly labeled with hazard information. Store separately from incompatible materials such as strong oxidizers, bases, and reducing agents. Maintain storage temperatures below 25°C when possible and ensure adequate containment to prevent environmental release. Implement regular inventory checks and proper segregation protocols.

Immediate action is required upon contact with 1-[(2,4-dichlorophenyl)carbamoyl]cyclopropane-1-carboxylic acid. For skin contact, remove contaminated clothing and rinse affected areas with plenty of water for at least 15 minutes. In case of eye contact, flush immediately with clean water for 15-20 minutes while holding eyelids open. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek medical attention promptly. Always consult safety data sheets and contact emergency services when necessary.

1-[(2,4-dichlorophenyl)carbamoyl]cyclopropane-1-carboxylic acid must be disposed of through licensed hazardous waste contractors due to its toxicity and environmental classification. The compound cannot be discharged into sewers, waterways, or regular waste streams due to its Aquatic Chronic 2 classification. Collect waste in appropriate containers, properly labeled and segregated from other materials. Consult local environmental regulations and engage certified waste management companies for safe disposal via incineration or other approved methods.

1-[(2,4-dichlorophenyl)carbamoyl]cyclopropane-1-carboxylic acid is classified under ADR Class 6.1 (Toxic substances), Packing Group III for transportation. This classification requires specific packaging, labeling, and documentation according to dangerous goods regulations. Packages must bear appropriate hazard labels and proper shipping names. Transport vehicles require proper placarding and drivers need ADR certification. Ensure compliance with international transport regulations and use approved packaging materials designed for Class 6.1 substances.

1-[(2,4-dichlorophenyl)carbamoyl]cyclopropane-1-carboxylic acid is subject to REACH regulation for registration and authorization within the European Union, though it is not classified as a Substance of Very High Concern (SVHC). The compound falls under CLP regulation for classification, labeling, and packaging requirements. Transport regulations under ADR Class 6.1 apply for shipping. Users must maintain safety data sheets, implement risk assessments, and follow occupational exposure limits where established by national authorities.

1-[(2,4-dichlorophenyl)carbamoyl]cyclopropane-1-carboxylic acid is available through OYSI, a specialized European distributor of technical chemicals and pharmaceutical intermediates. OYSI provides reliable supply chains across Europe with proper documentation, safety data sheets, and regulatory compliance support. As a professional chemical distributor, OYSI ensures product quality, appropriate packaging, and adherence to transport regulations. Contact OYSI directly for availability, technical specifications, and procurement information for this specialized chemical compound.