1-[(2,4-dichlorophenyl)carbamoyl]cyclopropane-1-carboxylic acid

1-[(2,4-dichlorophenyl)carbamoyl]cyclopropane-1-carboxylic acid is an organic chemical compound with the molecular formula C11H9Cl2NO3 and CAS number 113136-77-9. This substance features a cyclopropane ring structure combined with a dichlorophenyl group and carbamoyl functionality. With a molecular weight of 274.1 g/mol, it is classified as moderately toxic and presents environmental hazards to aquatic life. The compound requires careful handling due to its toxicological profile and regulatory classification under GHS.

1-[(2,4-dichlorophenyl)carbamoyl]cyclopropane-1-carboxylic acid is a solid organic compound at room temperature with a molecular weight of 274.1 g/mol. The presence of carboxylic acid functionality suggests moderate polarity and potential water solubility under appropriate pH conditions. The dichlorophenyl group contributes to its lipophilic character, while the cyclopropane ring provides structural rigidity. Specific physical properties such as melting point, boiling point, and exact solubility parameters would require detailed analytical characterization for precise determination.

1-[(2,4-dichlorophenyl)carbamoyl]cyclopropane-1-carboxylic acid is primarily used as a chemical intermediate in pharmaceutical and agrochemical synthesis. Its unique structural features, combining cyclopropane and dichlorophenyl moieties, make it valuable for developing bioactive compounds. The substance serves in research and development applications, particularly in medicinal chemistry where cyclopropane-containing molecules are explored for their biological activity. Industrial applications may include specialty chemical manufacturing and custom synthesis for pharmaceutical companies requiring this specific structural framework.

Safe handling of 1-[(2,4-dichlorophenyl)carbamoyl]cyclopropane-1-carboxylic acid requires appropriate personal protective equipment including safety glasses, chemical-resistant gloves, and laboratory coats. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid direct skin and eye contact, and prevent ingestion. The Acute Tox. 4 classification indicates moderate toxicity, necessitating careful handling procedures. Always wash hands thoroughly after handling and ensure emergency procedures are readily available in case of accidental exposure.

Proper storage of 1-[(2,4-dichlorophenyl)carbamoyl]cyclopropane-1-carboxylic acid requires a cool, dry, and well-ventilated area away from incompatible materials. Store in tightly sealed original containers to prevent moisture absorption and contamination. Keep away from strong oxidizing agents, bases, and heat sources. The storage area should be equipped with appropriate spill containment measures and restricted access. Given its aquatic toxicity classification, prevent release to the environment and ensure secondary containment systems are in place to protect groundwater and surface water.

In case of skin contact with 1-[(2,4-dichlorophenyl)carbamoyl]cyclopropane-1-carboxylic acid, immediately remove contaminated clothing and flush the affected area with plenty of water for at least 15 minutes. For eye contact, rinse thoroughly with water while holding eyelids open. If inhaled, move to fresh air immediately. In case of ingestion, do not induce vomiting and seek immediate medical attention. Remove person from exposure and provide supportive care. Always consult a physician and provide the safety data sheet for proper medical treatment.

Disposal of 1-[(2,4-dichlorophenyl)carbamoyl]cyclopropane-1-carboxylic acid must comply with local, national, and international environmental regulations. Due to its Aquatic Chronic 2 classification, prevent release to water systems and soil. Contact licensed hazardous waste disposal companies for proper treatment and disposal. Incineration at appropriate high-temperature facilities may be suitable, ensuring proper scrubbing of combustion gases. Never dispose of through regular waste streams or pour down drains. Maintain detailed waste disposal records for regulatory compliance and environmental protection.

Transportation of 1-[(2,4-dichlorophenyl)carbamoyl]cyclopropane-1-carboxylic acid follows ADR Class 6.1 (toxic substances) Packing Group III regulations. This classification indicates moderate toxicity requiring appropriate packaging, labeling, and documentation. Shipments must include proper hazard labels, transport documents, and emergency response information. Packages should be robust, leak-proof, and clearly marked with UN identification numbers. Transport vehicles require appropriate placarding and drivers need ADR training certification. Ensure compliance with international transport regulations including IMDG for sea transport and IATA for air transport.

1-[(2,4-dichlorophenyl)carbamoyl]cyclopropane-1-carboxylic acid is subject to REACH regulation for registration, evaluation, and authorization in the European Union. Under CLP regulation, it requires classification and labeling with GHS07 and GHS09 pictograms and 'Warning' signal word. The substance is not currently identified as SVHC (Substance of Very High Concern). Manufacturers and importers must comply with safety data sheet requirements and tonnage-based registration obligations. National chemical inventory listings and workplace exposure limits may apply depending on the country of use.

OYSI serves as a reliable European distributor for 1-[(2,4-dichlorophenyl)carbamoyl]cyclopropane-1-carboxylic acid, providing high-quality chemical products to industrial and research customers across Europe. As an established chemical distributor, OYSI ensures proper handling, storage, and transport compliance with European regulations. The company offers technical support and regulatory documentation including safety data sheets and certificates of analysis. Contact OYSI directly for availability, specifications, and pricing information to meet your specific application requirements while ensuring full regulatory compliance throughout the European market.