1,1,1,3,3,3-hexachloropropan-2-one

1,1,1,3,3,3-hexachloropropan-2-one is a halogenated organic compound with the molecular formula C3Cl6O and CAS number 116-16-5. This chemical compound has a molecular weight of 264.7 g/mol and belongs to the ketone family, featuring six chlorine atoms attached to a three-carbon chain with a central carbonyl group. It is classified as moderately toxic (Acute Tox. 4) and poses chronic aquatic toxicity concerns (Aquatic Chronic 2).

1,1,1,3,3,3-hexachloropropan-2-one is a dense liquid at room temperature due to its high chlorine content. The compound typically appears as a colorless to pale yellow liquid with a characteristic pungent odor. Its high molecular weight of 264.7 g/mol and extensive halogenation result in low volatility and limited water solubility, while it shows good solubility in organic solvents such as alcohols and chlorinated compounds.

1,1,1,3,3,3-hexachloropropan-2-one is primarily used as an intermediate in organic synthesis and chemical manufacturing processes. The compound serves as a reagent in the production of specialized chemicals and pharmaceuticals, particularly where halogenated ketone functionality is required. Its unique structure makes it valuable for research applications in organic chemistry and as a building block for more complex molecular structures in industrial chemical synthesis.

1,1,1,3,3,3-hexachloropropan-2-one requires careful handling due to its Acute Tox. 4 classification. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and protective clothing. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid skin and eye contact, and ensure emergency eyewash stations and safety showers are readily accessible. Always follow established laboratory safety protocols when handling this substance.

1,1,1,3,3,3-hexachloropropan-2-one should be stored in tightly sealed containers in a cool, dry, and well-ventilated area away from heat sources and ignition points. Keep containers in secondary containment to prevent spills and avoid storage near incompatible materials such as strong bases, reducing agents, and metals. The storage area should be equipped with appropriate spill control measures and maintained at stable temperatures to prevent degradation of the chemical.

In case of skin contact with 1,1,1,3,3,3-hexachloropropan-2-one, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, flush eyes immediately with clean water for at least 15 minutes while keeping eyelids open. If inhaled, move the person to fresh air immediately. Seek medical attention promptly for any exposure, especially if symptoms develop. Do not induce vomiting if ingested.

1,1,1,3,3,3-hexachloropropan-2-one must be disposed of as hazardous waste through licensed waste management companies in accordance with local and European regulations. The substance cannot be disposed of in regular waste streams due to its toxicity and environmental impact classification (Aquatic Chronic 2). Containers should be properly labeled and segregated from other waste types. Contact certified hazardous waste disposal services for collection and treatment according to applicable environmental legislation.

1,1,1,3,3,3-hexachloropropan-2-one is classified under ADR as Class 6.1 (toxic substances), Packing Group III, indicating moderate toxicity during transport. The substance requires appropriate UN-specification packaging and proper hazard labeling including toxic substance markings. Transport documentation must include the correct shipping name, UN number, and hazard class. Only trained personnel should handle the substance during transport, and emergency response information must be readily available throughout the shipping process.

1,1,1,3,3,3-hexachloropropan-2-one is subject to European REACH regulation requiring registration for import and use above specified tonnages. The substance must be classified and labeled according to CLP regulation, displaying GHS07 and GHS09 pictograms with 'Warning' signal word. While not currently listed as a Substance of Very High Concern (SVHC), its Aquatic Chronic 2 classification may trigger additional environmental monitoring requirements and usage restrictions in certain applications.

1,1,1,3,3,3-hexachloropropan-2-one is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides this compound to qualified industrial and research customers across Europe, ensuring proper regulatory compliance and safe handling guidelines. As a professional chemical distributor, OYSI maintains appropriate documentation, safety data sheets, and technical support for customers requiring this specialized halogenated ketone for their applications. Contact OYSI directly for availability and technical specifications.