2-anilinoacetic acid

C8H9NO2

CAS103-01-5

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Identification

CAS Number
103-01-5
EC Number
203-070-2
UN Number
PubChem CID
66025

Physical-chemical properties

Molecular Formula
C8H9NO2
Molar Mass
151.16 g/mol
IUPAC Name
2-anilinoacetic acid

Chemical Identifiers

InChI
InChI=1S/C8H9NO2/c10-8(11)6-9-7-4-2-1-3-5-7/h1-5,9H,6H2,(H,10,11)
InChI Key
NPKSPKHJBVJUKB-UHFFFAOYSA-N

Overview

2-anilinoacetic acid (CAS 103-01-5) is an organic compound featuring both aniline and carboxylic acid functional groups with intermediate molecular properties. This aromatic amino acid derivative represents an important building block in organic synthesis and pharmaceutical chemistry. With the molecular formula C8H9NO2 and a molecular weight of 151.16 g/mol, 2-anilinoacetic acid combines the reactivity of both amino and carboxyl functionalities, making it valuable for various chemical transformations and synthetic applications. The compound exhibits typical properties of substituted anilines and carboxylic acids, displaying amphoteric behavior due to the presence of both basic amino and acidic carboxyl groups. This dual functionality enables diverse chemical reactions including amide formation, esterification, and aromatic substitution reactions. The molecule's structure allows for intermolecular hydrogen bonding, influencing its physical properties and solubility characteristics. From a safety perspective, 2-anilinoacetic acid presents no specific hazard classifications under current regulatory frameworks, indicating relatively benign handling characteristics under normal industrial conditions. However, standard laboratory safety protocols should always be observed when working with any chemical substance. Primary industrial applications include its use as an intermediate in pharmaceutical synthesis, particularly in the development of anti-inflammatory compounds and other therapeutic agents. The compound also serves as a precursor in the manufacture of specialty chemicals and serves as a key building block in organic synthesis for research and development applications. Additionally, it finds utility in the production of certain dyes and pigments where its aromatic amine structure provides essential chromophoric properties. OYSI maintains reliable supply chains for 2-anilinoacetic acid to support European industrial and research requirements across multiple sectors.

Safety & Classification

No Hazard Classification

This substance is not classified as hazardous according to CLP Regulation (EC) No 1272/2008.

Frequently Asked Questions

What is 2-anilinoacetic acid?

2-anilinoacetic acid is an organic compound with the molecular formula C8H9NO2 and CAS number 103-01-5. This aromatic amino acid derivative consists of an aniline group attached to acetic acid, creating a compound with both aromatic and carboxylic acid functionalities. With a molecular weight of 151.16 g/mol, it serves as an important intermediate in pharmaceutical and chemical synthesis applications.

What are the physicochemical properties of 2-anilinoacetic acid?

2-anilinoacetic acid is typically a crystalline solid at room temperature with a white to off-white appearance. The compound contains both amino and carboxylic acid functional groups, making it amphoteric in nature. It shows moderate solubility in polar solvents due to its ability to form hydrogen bonds through both the amino and carboxyl groups, while the aromatic ring provides some hydrophobic character.

What is 2-anilinoacetic acid used for?

2-anilinoacetic acid is primarily used as an intermediate in pharmaceutical synthesis and organic chemistry applications. It serves as a building block for the production of various pharmaceutical compounds, dyes, and specialty chemicals. The compound's dual functionality makes it valuable in peptide synthesis and as a precursor for more complex aromatic compounds in research and industrial applications.

How to handle 2-anilinoacetic acid safely?

2-anilinoacetic acid should be handled using standard laboratory safety practices including wearing appropriate personal protective equipment such as safety glasses, gloves, and lab coats. Work should be conducted in well-ventilated areas or under fume hoods to minimize inhalation exposure. Avoid direct skin contact and ensure proper hygiene measures are followed when working with this organic compound.

How to store 2-anilinoacetic acid correctly?

2-anilinoacetic acid should be stored in tightly sealed containers in a cool, dry place away from direct sunlight and heat sources. The storage area should be well-ventilated and separated from incompatible materials such as strong oxidizing agents. Containers should be properly labeled and stored according to local chemical storage regulations to maintain product integrity and safety.

What to do in case of contact with 2-anilinoacetic acid?

In case of skin contact with 2-anilinoacetic acid, immediately wash the affected area with plenty of water for at least 15 minutes and remove contaminated clothing. For eye contact, flush thoroughly with water and seek medical attention. If inhaled, move to fresh air immediately. In case of ingestion, do not induce vomiting and seek immediate medical attention while providing the safety data sheet to medical personnel.

How to dispose of 2-anilinoacetic acid appropriately?

2-anilinoacetic acid should be disposed of according to local and national waste regulations as chemical waste. Contact licensed waste disposal companies for proper handling and treatment. Do not dispose of this compound through regular waste streams or pour down drains. Small quantities may be neutralized and treated according to institutional waste management protocols under proper supervision.

How to transport 2-anilinoacetic acid?

2-anilinoacetic acid does not appear to have specific ADR classification requirements based on available data, suggesting it may not be classified as dangerous goods for transport purposes. However, it should still be packaged securely in appropriate containers with proper labeling and documentation. Consult current transport regulations and safety data sheets for the most up-to-date shipping requirements and classifications.

Is 2-anilinoacetic acid subject to specific regulations?

2-anilinoacetic acid is subject to standard chemical regulations including REACH registration requirements for substances manufactured or imported in quantities above one tonne per year in the EU. It is not classified as a Substance of Very High Concern (SVHC) and does not carry specific GHS hazard classifications. Standard chemical handling and workplace safety regulations apply to its use and distribution.

Where to buy 2-anilinoacetic acid in Europe?

2-anilinoacetic acid is available through OYSI, a European distributor of chemical products, which can provide this compound for industrial and research applications. OYSI offers reliable supply chains and technical support for customers across Europe. Contact OYSI directly for availability, specifications, and delivery options tailored to your specific requirements and applications.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.