(4-nitrophenyl)hydrazine

(4-nitrophenyl)hydrazine is an organic chemical compound with the molecular formula C6H7N3O2 and CAS number 100-16-3. This aromatic hydrazine derivative features a nitro group (-NO2) attached to the para position of a phenyl ring connected to a hydrazine moiety. With a molecular weight of 153.14 g/mol, it serves as an important intermediate in organic synthesis and pharmaceutical manufacturing.

(4-nitrophenyl)hydrazine typically appears as a crystalline solid with a yellowish to orange color at room temperature. The compound exhibits moderate solubility in polar organic solvents and limited solubility in water. It has a melting point around 157-159°C and demonstrates stability under normal storage conditions, though it should be protected from light and oxidizing agents to prevent degradation.

(4-nitrophenyl)hydrazine serves primarily as a chemical intermediate in pharmaceutical synthesis and organic chemistry research. It is commonly used in the preparation of various pharmaceutical compounds, dyes, and other fine chemicals. The compound also finds application in analytical chemistry as a derivatizing agent and in the synthesis of heterocyclic compounds for research purposes.

(4-nitrophenyl)hydrazine should be handled with appropriate personal protective equipment including safety goggles, gloves, and lab coats. Work should be conducted in well-ventilated areas or under fume hoods to minimize inhalation exposure. Avoid direct skin and eye contact, and ensure proper hygiene practices. Keep away from heat sources, flames, and incompatible materials during handling operations.

(4-nitrophenyl)hydrazine should be stored in tightly sealed containers in a cool, dry place away from direct sunlight and heat sources. Keep the material separated from oxidizing agents, acids, and other incompatible substances. Storage areas should be well-ventilated and temperature-controlled. Regular inspection of containers for signs of deterioration or contamination is recommended for maintaining product quality.

In case of skin contact with (4-nitrophenyl)hydrazine, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, flush with clean water for 15 minutes while holding eyelids open. If inhaled, move to fresh air immediately. Seek medical attention if irritation persists or if large amounts were involved.

(4-nitrophenyl)hydrazine must be disposed of according to local, national, and international waste regulations. Contact licensed waste disposal companies specializing in chemical waste management. Do not discharge into drains, waterways, or soil. Small laboratory quantities may require special collection procedures, while larger industrial amounts need professional hazardous waste treatment. Always consult current regulatory guidelines before disposal.

(4-nitrophenyl)hydrazine is classified under ADR Class 4.1 (Flammable solids), Packing Group I, indicating it requires specific transport precautions. Packages must meet UN specification requirements and be properly labeled and documented. Transportation should be handled by certified carriers familiar with hazardous materials regulations. Ensure proper segregation from incompatible materials during transit and maintain appropriate documentation throughout the shipping process.

(4-nitrophenyl)hydrazine is subject to various chemical regulations including REACH registration requirements in Europe. While not currently listed as a Substance of Very High Concern (SVHC), it must comply with CLP classification and labeling regulations. Users should maintain safety data sheets, conduct risk assessments, and follow occupational exposure guidelines. Regular monitoring of regulatory updates ensures continued compliance.

(4-nitrophenyl)hydrazine is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides reliable supply chains for pharmaceutical intermediates and fine chemicals across European markets. As an established chemical distributor, OYSI ensures proper documentation, regulatory compliance, and quality standards for industrial and research applications. Contact OYSI directly for specific availability, packaging options, and technical support.