2-aminoethanol

C2H7NO

CAS141-43-5
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS05 Gefahrensymbol: Ätzend – Ätzwirkung
Danger

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Identification

CAS Number
141-43-5
EC Number
205-483-3
UN Number
2491
Index Number
603-030-00-8
PubChem CID
700

Physical-chemical properties

Molecular Formula
C2H7NO
Molar Mass
61.08 g/mol
IUPAC Name
2-aminoethanol

Chemical Identifiers

InChI
InChI=1S/C2H7NO/c3-1-2-4/h4H,1-3H2
InChI Key
HZAXFHJVJLSVMW-UHFFFAOYSA-N

Overview

2-aminoethanol (CAS 141-43-5) is an organic compound combining amine and alcohol functional groups with versatile industrial applications. This bifunctional molecule, also known as ethanolamine or monoethanolamine, represents one of the most important amino alcohols in industrial chemistry. With its molecular formula C2H7NO and molecular weight of 61.08 g/mol, 2-aminoethanol exhibits unique properties due to the presence of both hydroxyl and amino groups within its structure. This dual functionality makes it particularly valuable as a chemical intermediate and processing agent across multiple industries. The compound appears as a colorless, viscous liquid with a characteristic ammonia-like odor and demonstrates excellent water solubility. Its chemical versatility stems from the ability of both functional groups to participate in various reactions, including condensation, substitution, and complexation processes. 2-aminoethanol belongs to the broader family of ethanolamines, sharing structural similarities with compounds like 2-(diethylamino)ethanol, though each offers distinct reactivity profiles and applications. Safety considerations are paramount when handling 2-aminoethanol, as it is classified as corrosive to skin (Skin Corr. 1B) and presents acute toxicity hazards. The substance requires careful handling procedures, appropriate personal protective equipment, and adherence to ADR Class 8 transportation regulations. The GHS07 and GHS05 pictograms with "Danger" signal word emphasize the need for proper safety protocols. Primary industrial applications include gas treating processes for CO2 and H2S removal, production of detergents and surfactants, and synthesis of pharmaceutical intermediates. The compound also serves as a corrosion inhibitor and pH adjuster in various formulations. OYSI provides high-quality 2-aminoethanol to meet diverse industrial requirements across European markets.

Safety & Classification

Danger
Classification:

Acute Tox. 4 *; Acute Tox. 4 *; Acute Tox. 4 *; Skin Corr. 1B

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H332

Harmful if inhaled.

H312

Harmful in contact with skin.

H302

Harmful if swallowed.

H314

Causes severe skin burns and eye damage.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Harmful

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Harmful

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2491
ADR Class8
Packing GroupIII
Tunnel CodeE
Proper Shipping NameEthanolamin
Marine PollutantNo

Frequently Asked Questions

What is 2-aminoethanol?

2-aminoethanol is an organic compound with the molecular formula C2H7NO and CAS number 141-43-5. It is a bifunctional molecule containing both an amino group (-NH2) and a hydroxyl group (-OH), making it both an amine and an alcohol. With a molecular weight of 61.08 g/mol, this colorless liquid serves as an important industrial intermediate and chemical building block in various manufacturing processes.

What are the physicochemical properties of 2-aminoethanol?

2-aminoethanol is a colorless, viscous liquid at room temperature with a characteristic ammonia-like odor. It is highly hygroscopic and completely miscible with water due to its polar nature and ability to form hydrogen bonds. The compound has a boiling point of approximately 171°C and a melting point of 10.5°C. It is also soluble in alcohols and other polar solvents, making it versatile for various chemical applications.

What is 2-aminoethanol used for?

2-aminoethanol serves multiple industrial purposes as a versatile chemical intermediate. It is primarily used in the production of pharmaceuticals, agrochemicals, and surfactants. The compound acts as a corrosion inhibitor in metalworking fluids, a pH adjuster in cosmetic formulations, and a precursor for ethylene amines production. Additionally, it finds applications in textile processing, gas treatment for CO2 removal, and as a building block for various specialty chemicals.

How to handle 2-aminoethanol safely?

2-aminoethanol requires careful handling due to its corrosive properties (Skin Corr. 1B) and acute toxicity classification. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and protective clothing to prevent skin and eye contact. Work in well-ventilated areas or use local exhaust ventilation to minimize inhalation exposure. Avoid contact with incompatible materials and always have emergency eyewash stations and safety showers readily accessible in the work area.

How to store 2-aminoethanol correctly?

2-aminoethanol should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Keep containers upright and protected from physical damage. Due to its corrosive nature, store away from metals, acids, and oxidizing agents to prevent incompatible reactions. Ensure storage areas have appropriate spill containment measures and maintain temperatures below 25°C to preserve product stability and prevent vapor formation.

What to do in case of contact with 2-aminoethanol?

In case of skin contact with 2-aminoethanol, immediately remove contaminated clothing and flush the affected area with plenty of water for at least 15 minutes. For eye contact, rinse immediately with water for at least 15 minutes while holding eyelids open. If inhaled, move the person to fresh air and seek medical attention if breathing difficulties occur. In case of ingestion, do not induce vomiting and seek immediate medical attention. Always consult safety data sheets for detailed first aid procedures.

How to dispose of 2-aminoethanol properly?

2-aminoethanol disposal must comply with local, national, and international waste regulations due to its hazardous classification. The substance should never be poured down drains or released into the environment. Arrange disposal through licensed hazardous waste contractors who can handle corrosive materials appropriately. Small quantities may be neutralized under controlled conditions before disposal, but this should only be performed by trained personnel following established protocols and regulatory requirements.

How to transport 2-aminoethanol?

2-aminoethanol is classified as ADR Class 8 (corrosive substances), Packing Group III for transportation purposes. It must be packaged in UN-approved containers suitable for corrosive liquids and properly labeled with appropriate hazard markings and documentation. Transport vehicles must carry emergency response information and drivers require ADR training. Ensure packages are secured to prevent damage during transit and comply with quantity limitations and segregation requirements for Class 8 materials.

Is 2-aminoethanol subject to specific regulations?

2-aminoethanol is subject to various regulatory frameworks including REACH registration in Europe, where it must comply with registration requirements for substances manufactured or imported above certain tonnages. The substance is classified under CLP regulation with specific hazard classifications (Acute Tox. 4, Skin Corr. 1B). However, it is not currently listed as a Substance of Very High Concern (SVHC). Users must comply with occupational exposure limits and workplace safety regulations in their respective countries.

Where to buy 2-aminoethanol in Europe?

2-aminoethanol is available through OYSI, a reliable European distributor of technical chemicals serving industrial customers across the continent. OYSI provides quality chemical products with proper documentation including safety data sheets, certificates of analysis, and regulatory compliance information. As a specialized chemical distributor, OYSI ensures proper handling, storage, and transportation of hazardous materials like 2-aminoethanol while maintaining high standards of customer service and technical support for industrial applications.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.