2-(7-ethyl-1H-indol-3-yl)ethanol

C12H15NO

CAS41340-36-7
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
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Identification

CAS Number
41340-36-7
EC Number
431-020-1
UN Number
3077
Index Number
603-196-00-1
PubChem CID
198231

Physical-chemical properties

Molecular Formula
C12H15NO
Molar Mass
189.25 g/mol
IUPAC Name
2-(7-ethyl-1H-indol-3-yl)ethanol

Chemical Identifiers

InChI
InChI=1S/C12H15NO/c1-2-9-4-3-5-11-10(6-7-14)8-13-12(9)11/h3-5,8,13-14H,2,6-7H2,1H3
InChI Key
UVSDNCAZVSQJQA-UHFFFAOYSA-N

Overview

2-(7-ethyl-1H-indol-3-yl)ethanol (CAS 41340-36-7) is an indole derivative compound with ethyl substitution and ethanol functional group properties. This specialized indole compound represents an important class of heterocyclic organic molecules widely utilized in pharmaceutical intermediates and fine chemical synthesis. The molecule features a distinctive indole ring system with an ethyl substituent at the 7-position and an ethanol side chain at the 3-position, providing unique reactivity patterns and biological activity potential. With a molecular formula of C12H15NO and molecular weight of 189.25 g/mol, this compound exhibits moderate complexity suitable for various synthetic applications. The substance is classified under multiple hazard categories including Acute Toxicity Category 4, Specific Target Organ Toxicity Repeated Exposure Category 2, and Aquatic Chronic Toxicity Category 2, requiring appropriate handling protocols and environmental considerations. The GHS07, GHS08, and GHS09 pictograms indicate health hazards, chronic health effects, and environmental concerns respectively. Transportation falls under ADR Class 9 for miscellaneous dangerous substances. Primary industrial applications include pharmaceutical intermediate synthesis, particularly in the development of tryptamine derivatives and related bioactive compounds. The compound also serves in specialty chemical manufacturing and research applications where indole-based structures are required. Unlike simpler aromatic compounds such as 1,4-dichlorobenzene, this indole derivative offers more sophisticated functionality for complex molecular assemblies. OYSI provides 2-(7-ethyl-1H-indol-3-yl)ethanol with comprehensive technical support and regulatory documentation to meet European chemical distribution standards for pharmaceutical and specialty chemical industries.

Safety & Classification

Warning
Classification:

Acute Tox. 4 *; STOT RE 2 *; Aquatic Chronic 2

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H302

Harmful if swallowed.

H373

May cause damage to organs through prolonged or repeated exposure.

H411

Toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number3077
ADR Class9
Packing GroupIII
Tunnel Code-
Proper Shipping Name2-(7-Ethyl-1H-indol-3-yl)ethanol, fest
Marine PollutantNo

Frequently Asked Questions

What is 2-(7-ethyl-1H-indol-3-yl)ethanol?

2-(7-ethyl-1H-indol-3-yl)ethanol is an organic compound with the molecular formula C12H15NO and CAS number 41340-36-7. This indole derivative has a molecular weight of 189.25 g/mol and features an ethyl-substituted indole ring connected to an ethanol side chain. It is classified as a hazardous substance with acute toxicity and specific target organ toxicity properties, requiring careful handling in industrial applications.

What are the physicochemical properties of 2-(7-ethyl-1H-indol-3-yl)ethanol?

2-(7-ethyl-1H-indol-3-yl)ethanol is a solid organic compound at room temperature with a molecular weight of 189.25 g/mol. As an indole derivative containing both aromatic and alcohol functional groups, it likely exhibits moderate polarity and potential solubility in polar organic solvents. The compound's physical appearance and specific solubility parameters depend on purity and crystalline form, requiring detailed analysis for precise characterization.

What is 2-(7-ethyl-1H-indol-3-yl)ethanol used for?

2-(7-ethyl-1H-indol-3-yl)ethanol is primarily used in pharmaceutical research and chemical synthesis applications. As an indole derivative, it serves as a building block for drug development, particularly in neurological and psychiatric research. The compound may also function as an intermediate in organic synthesis for producing more complex molecules with biological activity, making it valuable for research institutions and pharmaceutical companies.

How to handle 2-(7-ethyl-1H-indol-3-yl)ethanol safely?

2-(7-ethyl-1H-indol-3-yl)ethanol requires careful handling due to its Acute Tox. 4 and STOT RE 2 classifications. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and laboratory coats. Work in well-ventilated areas or under fume hoods to minimize inhalation exposure. Avoid skin and eye contact, and ensure proper training before handling. Emergency shower and eyewash stations should be readily accessible in work areas.

How to store 2-(7-ethyl-1H-indol-3-yl)ethanol correctly?

2-(7-ethyl-1H-indol-3-yl)ethanol should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Keep containers protected from light and moisture to prevent degradation. Store separately from oxidizing agents and strong acids. Maintain storage temperature according to supplier specifications and ensure proper labeling with GHS pictograms (GHS07, GHS08, GHS09) for hazard identification.

What to do in case of contact with 2-(7-ethyl-1H-indol-3-yl)ethanol?

In case of skin contact with 2-(7-ethyl-1H-indol-3-yl)ethanol, immediately remove contaminated clothing and flush affected area with plenty of water for at least 15 minutes. For eye contact, rinse thoroughly with water for 15 minutes while holding eyelids open. If inhaled, move to fresh air immediately. Seek medical attention if irritation persists or if large quantities were involved. Never induce vomiting if ingested; rinse mouth and seek immediate medical attention.

How to dispose of 2-(7-ethyl-1H-indol-3-yl)ethanol properly?

2-(7-ethyl-1H-indol-3-yl)ethanol must be disposed of as hazardous waste according to local and national regulations. Contact licensed waste disposal companies for proper treatment and disposal. Never pour down drains or dispose of with regular waste due to its toxicity and environmental hazard classification (Aquatic Chronic 2). Contaminated containers should also be treated as hazardous waste. Maintain disposal records for regulatory compliance and traceability.

How to transport 2-(7-ethyl-1H-indol-3-yl)ethanol?

2-(7-ethyl-1H-indol-3-yl)ethanol is classified as ADR Class 9 (Miscellaneous dangerous substances), Packing Group III for transportation. Packages must be properly labeled with appropriate hazard markings and UN identification numbers. Use approved packaging materials and ensure compliance with ADR regulations for road transport. Carriers must have proper documentation including safety data sheets and transport documents. Professional hazardous goods transport services are recommended for safe delivery.

Is 2-(7-ethyl-1H-indol-3-yl)ethanol subject to specific regulations?

2-(7-ethyl-1H-indol-3-yl)ethanol is subject to REACH and CLP regulations in Europe, requiring proper registration and hazard classification. It is not currently listed as a Substance of Very High Concern (SVHC). Suppliers must provide safety data sheets complying with CLP requirements, including proper hazard pictograms (GHS07, GHS08, GHS09) and warning labels. Users must comply with occupational safety regulations and environmental protection requirements for handling and disposal.

Where to buy 2-(7-ethyl-1H-indol-3-yl)ethanol in Europe?

2-(7-ethyl-1H-indol-3-yl)ethanol is available through OYSI, a specialized European distributor of chemical products. OYSI provides this compound with full regulatory compliance, including proper documentation, safety data sheets, and hazard labeling according to European standards. As a professional chemical distributor, OYSI ensures quality products with appropriate packaging and transport arrangements for research institutions, pharmaceutical companies, and industrial users across Europe.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.