2-(7-ethyl-1H-indol-3-yl)ethanol

C12H15NO

CAS41340-36-7
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
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Identification

CAS Number
41340-36-7
EC Number
431-020-1
UN Number
3077
Index Number
603-196-00-1
PubChem CID
198231

Physical-chemical properties

Molecular Formula
C12H15NO
Molar Mass
189.25 g/mol
IUPAC Name
2-(7-ethyl-1H-indol-3-yl)ethanol

Chemical Identifiers

InChI
InChI=1S/C12H15NO/c1-2-9-4-3-5-11-10(6-7-14)8-13-12(9)11/h3-5,8,13-14H,2,6-7H2,1H3
InChI Key
UVSDNCAZVSQJQA-UHFFFAOYSA-N

Overview

2-(7-ethyl-1H-indol-3-yl)ethanol (CAS 41340-36-7) is an indole derivative compound featuring an ethyl-substituted indole ring structure with an ethanol side chain. This specialized organic compound belongs to the indole family, characterized by its bicyclic structure consisting of a benzene ring fused to a pyrrole ring. The presence of the 7-ethyl substitution and the 3-ethanol side chain provides unique chemical properties that distinguish it from other indole derivatives. With a molecular formula of C12H15NO and molecular weight of 189.25 g/mol, this compound exhibits specific reactivity patterns typical of substituted indoles. From a safety perspective, 2-(7-ethyl-1H-indol-3-yl)ethanol requires careful handling due to its classification as Acute Toxicity Category 4 and Specific Target Organ Toxicity Repeat Exposure Category 2. The compound also presents environmental concerns with its Aquatic Chronic Category 2 classification. These hazard classifications necessitate appropriate personal protective equipment and containment measures during handling and storage. The compound falls under ADR Class 9 for transportation, indicating it requires special handling procedures for shipping. Industrial applications for this indole derivative primarily center around pharmaceutical intermediates and specialized chemical synthesis. The compound serves as a building block in the development of bioactive molecules and can be utilized in the synthesis of complex organic compounds. Unlike simpler compounds such as 1,4-dichlorobenzene, this indole derivative offers more sophisticated structural features for advanced chemical applications. Research applications also extend to studies involving indole alkaloid synthesis and neurochemical research pathways. OYSI maintains reliable supply chains for 2-(7-ethyl-1H-indol-3-yl)ethanol, ensuring consistent availability for European industrial customers requiring this specialized indole compound.

Safety & Classification

Warning
Classification:

Acute Tox. 4 *; STOT RE 2 *; Aquatic Chronic 2

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H302

Harmful if swallowed.

H373

May cause damage to organs through prolonged or repeated exposure.

H411

Toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number3077
ADR Class9
Packing GroupIII
Tunnel Code-
Proper Shipping Name2-(7-Ethyl-1H-indol-3-yl)ethanol, fest
Marine PollutantNo

Frequently Asked Questions

What is 2-(7-ethyl-1H-indol-3-yl)ethanol?

2-(7-ethyl-1H-indol-3-yl)ethanol is an organic compound with the molecular formula C12H15NO and CAS number 41340-36-7. This indole derivative has a molecular weight of 189.25 g/mol and features an ethyl-substituted indole ring connected to an ethanol chain. It is classified as a hazardous substance with moderate toxicity and environmental impact concerns, requiring appropriate safety measures during handling and use.

What are the physicochemical properties of 2-(7-ethyl-1H-indol-3-yl)ethanol?

2-(7-ethyl-1H-indol-3-yl)ethanol is a solid organic compound at room temperature with a molecular weight of 189.25 g/mol. As an indole derivative containing both aromatic and alcohol functional groups, it typically exhibits limited water solubility but good solubility in organic solvents. The presence of the hydroxyl group provides some polar character, while the indole ring system contributes to its stability and specific chemical reactivity patterns.

What is 2-(7-ethyl-1H-indol-3-yl)ethanol used for?

2-(7-ethyl-1H-indol-3-yl)ethanol is primarily used as an intermediate in pharmaceutical and fine chemical synthesis. Its indole structure makes it valuable for developing biologically active compounds, particularly in medicinal chemistry research. The compound may also serve as a building block for producing specialty chemicals, agrochemicals, or other indole-based derivatives used in various industrial applications requiring specific molecular frameworks.

How to handle 2-(7-ethyl-1H-indol-3-yl)ethanol safely?

2-(7-ethyl-1H-indol-3-yl)ethanol requires careful handling due to its Acute Tox. 4 and STOT RE 2 classifications. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and protective clothing. Work in well-ventilated areas or under fume hoods to minimize inhalation exposure. Avoid direct skin contact and ingestion. Ensure proper training on emergency procedures and maintain eyewash stations and safety showers nearby during handling operations.

How to store 2-(7-ethyl-1H-indol-3-yl)ethanol correctly?

2-(7-ethyl-1H-indol-3-yl)ethanol should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Keep containers upright and properly labeled with hazard information. Store away from incompatible materials and ensure adequate spill containment measures. Maintain storage temperatures as recommended by the supplier and regularly inspect containers for signs of deterioration or leakage to prevent environmental contamination.

What to do in case of contact with 2-(7-ethyl-1H-indol-3-yl)ethanol?

Immediate action is required for any contact with 2-(7-ethyl-1H-indol-3-yl)ethanol. For skin contact, remove contaminated clothing and wash affected area thoroughly with soap and water for at least 15 minutes. In case of eye contact, rinse immediately with clean water for 15-20 minutes and remove contact lenses if present. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek medical attention promptly in all cases.

How to dispose of 2-(7-ethyl-1H-indol-3-yl)ethanol appropriately?

2-(7-ethyl-1H-indol-3-yl)ethanol waste must be disposed of through licensed hazardous waste contractors in accordance with local and European regulations. Due to its environmental classification (Aquatic Chronic 2), it cannot be discharged to sewers or waterways. Collect waste in appropriate containers, properly label with contents and hazard information, and maintain waste documentation. Consider recovery or recycling options where feasible before disposal to minimize environmental impact.

How to transport 2-(7-ethyl-1H-indol-3-yl)ethanol?

2-(7-ethyl-1H-indol-3-yl)ethanol is classified as ADR Class 9 (Miscellaneous Dangerous Substances), Packing Group III for transport purposes. This classification requires appropriate UN-specification packaging, proper labeling with Class 9 hazard labels, and transport documentation. Vehicles must carry appropriate emergency equipment and drivers need ADR certification. Packages should be secured to prevent movement during transport and protected from temperature extremes and physical damage.

Is 2-(7-ethyl-1H-indol-3-yl)ethanol subject to specific regulations?

2-(7-ethyl-1H-indol-3-yl)ethanol is subject to European REACH and CLP regulations requiring registration, classification, and labeling compliance. While not currently listed as a SVHC (Substance of Very High Concern), its hazard classifications mandate specific safety data sheet provisions and risk management measures. Users must comply with occupational exposure limits, environmental discharge restrictions, and waste management regulations. Regular monitoring of regulatory updates is essential for continued compliance.

Where to buy 2-(7-ethyl-1H-indol-3-yl)ethanol in Europe?

2-(7-ethyl-1H-indol-3-yl)ethanol is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides reliable supply chains across Europe with proper regulatory compliance, quality assurance, and technical support. As a professional chemical distributor, OYSI ensures appropriate packaging, documentation, and handling expertise for this regulated substance. Contact OYSI directly for availability, specifications, and delivery options to meet your specific requirements.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.