6-amino-N-methylnaphthalene-2-sulfonamide
C11H12N2O2S
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Identification
- CAS Number
- 104295-55-8
- EC Number
- 412-120-4
- UN Number
- 3077
- Index Number
- 612-177-00-7
- PubChem CID
- 3034961
Physical-chemical properties
- Molecular Formula
- C11H12N2O2S
- Molar Mass
- 236.29 g/mol
- IUPAC Name
- 6-amino-N-methylnaphthalene-2-sulfonamide
Chemical Identifiers
- InChI
- InChI=1S/C11H12N2O2S/c1-13-16(14,15)11-5-3-8-6-10(12)4-2-9(8)7-11/h2-7,13H,12H2,1H3
- InChI Key
- RBQODZRXIYFUJS-UHFFFAOYSA-N
Overview
6-amino-N-methylnaphthalene-2-sulfonamide (CAS 104295-55-8) is an aromatic sulfonamide compound with amino and methylamino functional groups providing versatile chemical reactivity. This specialized naphthalene derivative represents an important class of organic intermediates used in various industrial applications. With the molecular formula C11H12N2O2S and a molecular weight of 236.29 g/mol, this compound features both amino and sulfonamide functionalities that contribute to its chemical versatility. The EC number 412-120-4 designates its regulatory status within European chemical legislation. From a safety perspective, 6-amino-N-methylnaphthalene-2-sulfonamide carries specific hazard classifications including STOT RE 2, indicating potential organ toxicity upon repeated exposure, Skin Sens. 1 for skin sensitization properties, and Aquatic Chronic 2 for environmental considerations. The associated GHS pictograms (GHS08, GHS07, GHS09) and "Warning" signal word reflect these hazard profiles. Transportation falls under ADR Class 9, designating it as a miscellaneous dangerous substance requiring appropriate handling protocols. Industrial applications typically include use as a chemical intermediate in pharmaceutical synthesis, where its sulfonamide structure provides valuable building blocks for drug development. The compound also finds application in specialty dye manufacturing and as a precursor in the production of advanced materials. Its structural similarity to other industrial chemicals like 1,4-dichlorobenzene makes it valuable in comparative synthetic pathways, though its unique amino-sulfonamide configuration offers distinct reactivity profiles. Professional handlers appreciate the compound's stability under standard storage conditions while maintaining awareness of its sensitization potential and environmental impact considerations. OYSI provides reliable access to 6-amino-N-methylnaphthalene-2-sulfonamide for qualified industrial customers across European markets.
Safety & Classification
STOT RE 2 *; Skin Sens. 1; Aquatic Chronic 2
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Skin Contact
Measures if substance contacts the skin
First Aid Actions
- +P302IF ON SKIN:
- +P352Wash with plenty of water.
- +P361Take off immediately all contaminated clothing.
- +P313Get medical advice/attention.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 3077 |
| ADR Class | 9 |
| Packing Group | III |
| Tunnel Code | - |
| Proper Shipping Name | 6-Amino-N-methylnaphthalin-2-sulfonamid |
| Marine Pollutant | No |
Frequently Asked Questions
What is 6-amino-N-methylnaphthalene-2-sulfonamide?
6-amino-N-methylnaphthalene-2-sulfonamide is an organic chemical compound with the molecular formula C11H12N2O2S and CAS number 104295-55-8. This sulfonamide derivative features a naphthalene ring system with both amino and methylsulfonamide functional groups. With a molecular weight of 236.29 g/mol, it belongs to the aromatic sulfonamide family and is classified as a hazardous substance requiring proper handling precautions due to its potential health and environmental impacts.
What are the physicochemical properties of 6-amino-N-methylnaphthalene-2-sulfonamide?
6-amino-N-methylnaphthalene-2-sulfonamide is a solid organic compound at room temperature with a molecular weight of 236.29 g/mol. The presence of both amino and sulfonamide groups in its naphthalene structure influences its solubility characteristics and chemical reactivity. Specific physical properties such as melting point, boiling point, and exact solubility data should be obtained from the safety data sheet for precise handling and processing requirements.
What is 6-amino-N-methylnaphthalene-2-sulfonamide used for?
6-amino-N-methylnaphthalene-2-sulfonamide serves as an important intermediate in pharmaceutical and chemical synthesis applications. Its sulfonamide structure makes it valuable for developing pharmaceutical compounds, dyes, and other specialty chemicals. The compound's amino and sulfonamide functional groups provide reactive sites for further chemical modifications, making it useful in research and development activities within the pharmaceutical and fine chemical industries.
How to handle 6-amino-N-methylnaphthalene-2-sulfonamide safely?
6-amino-N-methylnaphthalene-2-sulfonamide requires careful handling due to its classification as a skin sensitizer and potential for repeated exposure toxicity. Use appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Ensure adequate ventilation to prevent inhalation exposure. Avoid skin contact and implement proper hygiene measures. Handle in designated areas with appropriate containment measures to prevent environmental release and cross-contamination.
How to store 6-amino-N-methylnaphthalene-2-sulfonamide correctly?
6-amino-N-methylnaphthalene-2-sulfonamide should be stored in a cool, dry, well-ventilated area away from incompatible materials. Keep containers tightly closed and properly labeled according to CLP regulations. Store away from heat sources, direct sunlight, and moisture to maintain product stability. Implement appropriate containment measures to prevent environmental release. Ensure storage areas comply with local regulations and have appropriate emergency response equipment readily available.
What to do in case of contact with 6-amino-N-methylnaphthalene-2-sulfonamide?
Immediate action is required following contact with 6-amino-N-methylnaphthalene-2-sulfonamide due to its skin sensitizing properties. For skin contact, remove contaminated clothing and wash affected area thoroughly with soap and water for at least 15 minutes. In case of eye contact, rinse immediately with clean water for 15-20 minutes. If inhaled, move to fresh air immediately. Seek medical attention if irritation persists or symptoms develop. Do not induce vomiting if ingested.
How to dispose of 6-amino-N-methylnaphthalene-2-sulfonamide appropriately?
6-amino-N-methylnaphthalene-2-sulfonamide must be disposed of as hazardous waste according to local and European regulations due to its classification and environmental impact potential. Contact licensed waste disposal companies specializing in chemical waste management. Never discharge into sewers, waterways, or soil. Ensure proper waste classification and documentation for tracking purposes. Consider recovery or recycling options where technically and economically feasible before disposal.
How to transport 6-amino-N-methylnaphthalene-2-sulfonamide?
6-amino-N-methylnaphthalene-2-sulfonamide is classified under ADR Class 9 (Miscellaneous dangerous substances), Packing Group III for transportation purposes. This classification requires appropriate packaging, labeling, and documentation according to dangerous goods regulations. Use UN-specification packaging and ensure proper hazard labels are affixed. Transportation must comply with ADR requirements including driver training, vehicle placarding, and emergency response information. Consult current dangerous goods regulations for specific requirements.
Is 6-amino-N-methylnaphthalene-2-sulfonamide subject to specific regulations?
6-amino-N-methylnaphthalene-2-sulfonamide is subject to REACH registration requirements and CLP classification and labeling regulations within the European Union. The substance is not currently listed as a Substance of Very High Concern (SVHC). Companies must comply with occupational exposure limits, environmental discharge restrictions, and proper hazard communication requirements. Regular monitoring of regulatory updates is essential as classifications and restrictions may change based on new scientific evidence.
Where to buy 6-amino-N-methylnaphthalene-2-sulfonamide in Europe?
6-amino-N-methylnaphthalene-2-sulfonamide is available through OYSI, a specialized European distributor of technical chemicals and pharmaceutical intermediates. OYSI provides compliant supply with proper documentation, safety data sheets, and regulatory support throughout Europe. The company ensures products meet European standards and provides technical expertise for safe handling and application. Contact OYSI directly for availability, specifications, and regulatory compliance information specific to your application requirements.
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Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.