2-[2-(dimethylamino)ethyldisulfanyl]-N,N-dimethylethanamine;dihydrochloride
C8H22Cl2N2S2
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Identification
- CAS Number
- 17339-60-5
- EC Number
- 405-300-9
- UN Number
- 3077
- Index Number
- 016-059-00-0
- PubChem CID
- 12574418
Physical-chemical properties
- Molecular Formula
- C8H22Cl2N2S2
- Molar Mass
- 281.30 g/mol
- IUPAC Name
- 2-[2-(dimethylamino)ethyldisulfanyl]-N,N-dimethylethanamine;dihydrochloride
Chemical Identifiers
- InChI
- InChI=1S/C8H20N2S2.2ClH/c1-9(2)5-7-11-12-8-6-10(3)4;;/h5-8H2,1-4H3;2*1H
- InChI Key
- OJNVDODUOWHJPK-UHFFFAOYSA-N
Overview
2-[2-(dimethylamino)ethyldisulfanyl]-N,N-dimethylethanamine dihydrochloride (CAS 17339-60-5) is an organosulfur compound with disulfide bridging and tertiary amine functionality. This specialized chemical compound, with molecular formula C8H22Cl2N2S2 and molecular weight 281.3 g/mol, represents an important class of bifunctional organosulfur chemicals used in various industrial applications. The compound features a characteristic disulfide bridge connecting two dimethylaminoethyl groups, with the dihydrochloride salt form providing enhanced stability and water solubility compared to the free base. Its unique structure combines the reactivity of disulfide bonds with the basicity of tertiary amines, making it valuable for specific chemical transformations and industrial processes. From a safety perspective, this compound requires careful handling due to its classification under multiple hazard categories. It presents acute toxicity concerns (Acute Tox. 4), can cause eye irritation (Eye Irrit. 2), and may cause allergic skin reactions (Skin Sens. 1). The compound also poses environmental risks with both acute and chronic aquatic toxicity classifications. The GHS07 and GHS09 pictograms indicate health hazards and environmental dangers respectively, while the ADR Class 9 classification designates it as a miscellaneous dangerous substance requiring special transport considerations. Industrial applications typically include use as a chemical intermediate in pharmaceutical synthesis, as a cross-linking agent in polymer chemistry, and in specialized analytical chemistry procedures. The disulfide functionality makes it particularly useful in biochemical applications where reversible cross-linking is desired, similar to applications found with other specialized compounds like 2-chloro-N-phenyl-N-propan-2-ylacetamide in pharmaceutical intermediates. OYSI provides this technical-grade compound to qualified industrial customers across Europe with appropriate documentation and safety data sheets.
Safety & Classification
Acute Tox. 4 *; Eye Irrit. 2; Skin Sens. 1; Aquatic Acute 1; Aquatic Chronic 1
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Skin Contact
Measures if substance contacts the skin
First Aid Actions
- +P302IF ON SKIN:
- +P352Wash with plenty of water.
- +P361Take off immediately all contaminated clothing.
- +P313Get medical advice/attention.
Related hazard statements:
Eye Contact
Measures if substance gets into the eyes
First Aid Actions
- +P305IF IN EYES:
- +P351Rinse cautiously with water for several minutes.
- +P338Remove contact lenses, if present and easy to do. Continue rinsing.
- +P313Get medical advice/attention.
Related hazard statements:
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 3077 |
| ADR Class | 9 |
| Packing Group | III |
| Tunnel Code | - |
| Proper Shipping Name | N,N,N',N'-Tetramethyldithio-bis(ethylen)-diamin-dihydrochlorid |
| Marine Pollutant | No |
Frequently Asked Questions
What is 2-[2-(dimethylamino)ethyldisulfanyl]-N,N-dimethylethanamine dihydrochloride?
2-[2-(dimethylamino)ethyldisulfanyl]-N,N-dimethylethanamine dihydrochloride is an organic compound with CAS number 17339-60-5 and molecular formula C8H22Cl2N2S2. This chemical features a disulfide bridge connecting two dimethylaminoethyl groups and exists as a dihydrochloride salt. With a molecular weight of 281.3 g/mol, it belongs to the class of organosulfur compounds containing tertiary amine functionalities, making it useful in various chemical applications requiring disulfide chemistry.
What are the physicochemical properties of 2-[2-(dimethylamino)ethyldisulfanyl]-N,N-dimethylethanamine dihydrochloride?
2-[2-(dimethylamino)ethyldisulfanyl]-N,N-dimethylethanamine dihydrochloride typically appears as a crystalline solid at room temperature due to its salt form. The presence of the dihydrochloride groups enhances its water solubility compared to the free base. The compound contains both hydrophilic amine groups and a hydrophobic disulfide bridge, giving it amphiphilic properties. Its stability is influenced by the disulfide bond, which can be sensitive to reducing conditions and pH changes.
What is 2-[2-(dimethylamino)ethyldisulfanyl]-N,N-dimethylethanamine dihydrochloride used for?
2-[2-(dimethylamino)ethyldisulfanyl]-N,N-dimethylethanamine dihydrochloride is primarily used in pharmaceutical research and chemical synthesis applications. Its disulfide functionality makes it valuable as a crosslinking agent or reducing agent precursor in biochemical studies. The compound may serve as an intermediate in the synthesis of more complex molecules or as a reagent in disulfide bond formation and cleavage reactions. It finds applications in research laboratories working on protein chemistry and drug development.
How to handle 2-[2-(dimethylamino)ethyldisulfanyl]-N,N-dimethylethanamine dihydrochloride safely?
2-[2-(dimethylamino)ethyldisulfanyl]-N,N-dimethylethanamine dihydrochloride requires careful handling due to its classification as Acute Tox. 4, Eye Irrit. 2, and Skin Sens. 1. Always wear appropriate personal protective equipment including safety goggles, gloves, and lab coats. Ensure adequate ventilation in work areas and avoid direct skin and eye contact. Handle in a well-ventilated area or fume hood to prevent inhalation. The compound may cause skin sensitization, so minimize exposure and wash hands thoroughly after handling.
How to store 2-[2-(dimethylamino)ethyldisulfanyl]-N,N-dimethylethanamine dihydrochloride correctly?
2-[2-(dimethylamino)ethyldisulfanyl]-N,N-dimethylethanamine dihydrochloride should be stored in a cool, dry place away from direct sunlight and heat sources. Keep containers tightly closed to prevent moisture absorption and contamination. Store away from strong oxidizing agents and reducing agents that could affect the disulfide bond. Ensure proper labeling and maintain storage temperatures as specified by the manufacturer. Keep away from incompatible materials and ensure storage areas are well-ventilated and secure.
What to do in case of contact with 2-[2-(dimethylamino)ethyldisulfanyl]-N,N-dimethylethanamine dihydrochloride?
In case of skin contact with 2-[2-(dimethylamino)ethyldisulfanyl]-N,N-dimethylethanamine dihydrochloride, immediately wash the affected area with plenty of water for at least 15 minutes and remove contaminated clothing. For eye contact, rinse eyes thoroughly with water for at least 15 minutes and seek immediate medical attention due to its eye irritant properties. If inhaled, move to fresh air immediately. If ingested, do not induce vomiting and seek medical attention. Always consult the safety data sheet and contact emergency services if severe symptoms develop.
How to dispose of 2-[2-(dimethylamino)ethyldisulfanyl]-N,N-dimethylethanamine dihydrochloride properly?
2-[2-(dimethylamino)ethyldisulfanyl]-N,N-dimethylethanamine dihydrochloride must be disposed of according to local and national environmental regulations due to its Aquatic Acute 1 and Aquatic Chronic 1 classifications. Never dispose of this chemical down drains or into waterways as it poses environmental hazards. Contact licensed waste disposal companies for proper chemical waste management. Small quantities may require special handling procedures. Always consult local environmental authorities and follow institutional waste disposal protocols for hazardous chemicals.
How to transport 2-[2-(dimethylamino)ethyldisulfanyl]-N,N-dimethylethanamine dihydrochloride?
2-[2-(dimethylamino)ethyldisulfanyl]-N,N-dimethylethanamine dihydrochloride is classified as ADR Class 9 (Miscellaneous dangerous goods), Packing Group III for transportation purposes. This classification requires appropriate packaging, labeling, and documentation according to dangerous goods regulations. Packages must be properly marked and labeled with the correct shipping name and hazard class. Ensure compliance with international transportation regulations including IATA for air transport and IMDG for maritime transport. Use authorized carriers experienced in handling chemical products.
Is 2-[2-(dimethylamino)ethyldisulfanyl]-N,N-dimethylethanamine dihydrochloride subject to special regulations?
2-[2-(dimethylamino)ethyldisulfanyl]-N,N-dimethylethanamine dihydrochloride is subject to REACH regulation in Europe and must comply with CLP classification requirements, as evidenced by its GHS07 and GHS09 pictograms and Warning signal word. The compound is not currently listed as a Substance of Very High Concern (SVHC). Users must ensure proper registration, evaluation, and authorization compliance. Safety data sheets must be provided and updated according to regulatory requirements. Companies handling this substance should maintain proper documentation and follow applicable chemical safety regulations.
Where to buy 2-[2-(dimethylamino)ethyldisulfanyl]-N,N-dimethylethanamine dihydrochloride in Europe?
2-[2-(dimethylamino)ethyldisulfanyl]-N,N-dimethylethanamine dihydrochloride is available through OYSI, a trusted European distributor of specialty chemicals. OYSI provides this compound to research institutions, pharmaceutical companies, and industrial customers across Europe with proper documentation and regulatory compliance. As a specialized chemical distributor, OYSI ensures quality products with appropriate safety data sheets and certificates of analysis. Contact OYSI directly for availability, specifications, and pricing information for your specific application requirements.
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2-[2-(dimethylamino)ethyldisulfanyl]-N,N-dimethylethanamine;dihydrochloride is a dangerous good. We support you with labeling, packaging, and transport documentation.
Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.