2-chloro-N-phenyl-N-propan-2-ylacetamide

2-chloro-N-phenyl-N-propan-2-ylacetamide is an organic chemical compound with the molecular formula C11H14ClNO and CAS number 1918-16-7. This acetamide derivative features a chlorinated carbon chain attached to a substituted aniline group. With a molecular weight of 211.69 g/mol, it belongs to the class of halogenated amides and is classified as moderately hazardous with acute toxicity, eye irritation, and skin sensitization properties.

2-chloro-N-phenyl-N-propan-2-ylacetamide is a solid organic compound at room temperature with moderate molecular weight of 211.69 g/mol. The presence of both polar (amide) and non-polar (phenyl, alkyl) groups suggests limited water solubility but good solubility in organic solvents. The chlorine substitution and aromatic ring contribute to its chemical stability under normal conditions, though specific physical parameters like melting point and solubility data require laboratory determination.

2-chloro-N-phenyl-N-propan-2-ylacetamide is primarily used as a chemical intermediate in pharmaceutical and agrochemical synthesis. Its acetamide structure with chlorine functionality makes it valuable for creating more complex molecules through substitution reactions. The compound serves in research applications and specialized chemical manufacturing processes where controlled reactivity and specific molecular architecture are required for developing active pharmaceutical ingredients or crop protection chemicals.

2-chloro-N-phenyl-N-propan-2-ylacetamide requires careful handling due to its Acute Tox. 4, Eye Irrit. 2, and Skin Sens. 1 classifications. Essential personal protective equipment includes safety goggles, chemical-resistant gloves, and protective clothing to prevent skin contact. Work in well-ventilated areas or under fume extraction to avoid inhalation. Handle containers carefully to prevent spills, and ensure emergency wash facilities are readily available for immediate decontamination if accidental contact occurs.

2-chloro-N-phenyl-N-propan-2-ylacetamide should be stored in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Keep containers tightly sealed to prevent moisture absorption and contamination. Due to its Aquatic Acute 1 and Chronic 1 classifications, ensure storage areas have appropriate containment measures to prevent environmental release. Store separately from incompatible materials such as strong oxidizers and bases, and maintain proper inventory tracking for regulatory compliance.

Immediate action is required for any contact with 2-chloro-N-phenyl-N-propan-2-ylacetamide due to its irritating and sensitizing properties. For skin contact, immediately remove contaminated clothing and wash affected area with plenty of soap and water for at least 15 minutes. For eye contact, rinse thoroughly with water for 15 minutes and remove contact lenses if present. If inhaled, move to fresh air immediately. Seek medical attention if symptoms persist or develop, and always show the safety data sheet to medical personnel.

2-chloro-N-phenyl-N-propan-2-ylacetamide must be disposed of as hazardous chemical waste through licensed waste management facilities due to its toxicity and environmental hazard classifications. Never discharge into sewers, water bodies, or soil as it poses acute and chronic aquatic toxicity risks. Collect waste in appropriate, labeled containers and arrange disposal through certified hazardous waste contractors. Follow local, national, and EU waste regulations, and maintain proper documentation of disposal activities for regulatory compliance.

2-chloro-N-phenyl-N-propan-2-ylacetamide is classified as ADR Class 9 (Miscellaneous Dangerous Substances), Packing Group III for transportation purposes. This classification requires appropriate packaging, labeling, and documentation according to dangerous goods regulations. Containers must be properly secured, labeled with correct hazard markings, and accompanied by transport documents. Drivers must hold appropriate dangerous goods certifications, and vehicles should carry emergency response information and spill containment materials during transport.

2-chloro-N-phenyl-N-propan-2-ylacetamide is subject to EU REACH regulation requiring registration for manufacture or import above one tonne annually. Under CLP regulation, it must be classified and labeled according to its hazard profile with GHS07 and GHS09 pictograms and 'Warning' signal word. While not currently identified as a Substance of Very High Concern (SVHC), users must comply with occupational exposure limits, environmental discharge restrictions, and maintain safety data sheets for workplace safety compliance.

2-chloro-N-phenyl-N-propan-2-ylacetamide is available through OYSI, a specialized European distributor of technical chemicals and pharmaceutical intermediates. OYSI provides reliable supply chains across Europe with proper documentation, safety data sheets, and regulatory compliance support. As a professional chemical distributor, OYSI ensures product quality, appropriate packaging, and technical support for industrial customers requiring this specialized acetamide compound for their manufacturing or research applications.