2-chloro-N-phenyl-N-propan-2-ylacetamide

2-chloro-N-phenyl-N-propan-2-ylacetamide is an organic chemical compound with the molecular formula C11H14ClNO and CAS number 1918-16-7. This acetamide derivative has a molecular weight of 211.69 g/mol and features a chlorinated acetyl group attached to a substituted aniline structure. The compound is classified as moderately hazardous with acute toxicity, eye irritation, and skin sensitization properties, requiring careful handling in industrial applications.

2-chloro-N-phenyl-N-propan-2-ylacetamide is a solid organic compound at room temperature with a molecular weight of 211.69 g/mol. The presence of both polar (amide, chloro) and nonpolar (phenyl, isopropyl) groups suggests moderate polarity and potential solubility in organic solvents. Its chlorinated acetamide structure indicates stability under normal conditions, though specific melting point, boiling point, and solubility data would require analytical characterization for precise values.

2-chloro-N-phenyl-N-propan-2-ylacetamide is primarily used as an intermediate in organic synthesis and pharmaceutical manufacturing. Its acetamide structure makes it valuable for producing more complex molecules through chemical modifications. The compound may serve as a building block in the synthesis of agrochemicals, pharmaceuticals, or specialty chemicals where the chloroacetamide functionality is required for further chemical transformations or as an active component in formulated products.

2-chloro-N-phenyl-N-propan-2-ylacetamide requires careful handling due to its Acute Tox. 4, Eye Irrit. 2, and Skin Sens. 1 classifications. Essential PPE includes chemical-resistant gloves, safety goggles, and protective clothing to prevent skin and eye contact. Work in well-ventilated areas or under fume extraction to avoid inhalation. Avoid generating dust and ensure immediate washing if skin contact occurs. The Warning signal word indicates moderate but significant hazard potential.

2-chloro-N-phenyl-N-propan-2-ylacetamide should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from incompatible materials. Keep containers protected from moisture and direct sunlight to prevent degradation. Due to its skin sensitizing properties and moderate toxicity, storage areas should be secure and accessible only to trained personnel. Maintain proper labeling with GHS pictograms (GHS07, GHS09) and ensure compliance with local chemical storage regulations.

Immediate action is required upon contact with 2-chloro-N-phenyl-N-propan-2-ylacetamide due to its irritating and sensitizing properties. For skin contact, immediately remove contaminated clothing and wash thoroughly with soap and water for at least 15 minutes. In case of eye contact, rinse immediately with plenty of water for 15 minutes and remove contact lenses if present. If inhaled, move to fresh air. Seek medical attention if symptoms persist or for significant exposures.

2-chloro-N-phenyl-N-propan-2-ylacetamide must be disposed of as hazardous waste due to its toxicity and environmental hazard classifications (Aquatic Acute 1, Aquatic Chronic 1). Contact licensed hazardous waste disposal companies for proper treatment and disposal. Never discharge to sewers, waterways, or soil. Small quantities may require incineration at appropriate high-temperature facilities. Follow local and European waste regulations including proper waste classification codes and documentation requirements for hazardous chemical disposal.

2-chloro-N-phenyl-N-propan-2-ylacetamide is classified as ADR Class 9 (Miscellaneous Dangerous Substances), Packing Group III for transport purposes. This classification indicates it presents a relatively lower transport hazard but still requires proper packaging, labeling, and documentation. Packages must bear appropriate hazard labels and shipping names according to ADR regulations. Transport should comply with quantity limitations and vehicle requirements specified for Class 9 substances, ensuring secure packaging to prevent leakage during transit.

2-chloro-N-phenyl-N-propan-2-ylacetamide is subject to standard European chemical regulations including REACH registration requirements and CLP classification obligations. The substance is not currently identified as a Substance of Very High Concern (SVHC). Suppliers must provide Safety Data Sheets and ensure proper GHS labeling with Warning signal word and pictograms GHS07 and GHS09. Additional restrictions may apply depending on specific applications and quantities used in industrial processes.

2-chloro-N-phenyl-N-propan-2-ylacetamide is available through OYSI, a specialized European distributor of technical chemicals and intermediates. OYSI provides reliable supply chains for industrial customers requiring this acetamide derivative for synthesis and manufacturing applications. As a European chemical distributor, OYSI ensures compliance with REACH and CLP regulations, providing proper documentation and technical support. Contact OYSI directly for availability, specifications, and pricing information tailored to your specific requirements.