Prop-2-ynyl (2R)-2-[4-[(5-chloro-3-fluoro-2-pyridinyl)oxy]phenoxy]propanoate

Prop-2-ynyl (2R)-2-[4-[(5-chloro-3-fluoro-2-pyridinyl)oxy]phenoxy]propanoate is a synthetic organic compound with the molecular formula C17H13ClFNO4 and CAS number 105512-06-9. This substance has a molecular weight of 349.7 g/mol and belongs to the class of halogenated pyridine derivatives. It contains chlorine and fluorine substituents on a pyridine ring system connected through ether linkages to a phenoxy group and a propanoate ester moiety with an alkyne functional group.

Prop-2-ynyl (2R)-2-[4-[(5-chloro-3-fluoro-2-pyridinyl)oxy]phenoxy]propanoate is an organic compound with molecular formula C17H13ClFNO4 and molecular weight 349.7 g/mol. The presence of halogen atoms (chlorine and fluorine) and multiple aromatic rings suggests it is likely a crystalline solid at room temperature. The compound contains both hydrophilic (ester, ether) and lipophilic (aromatic rings) groups, indicating moderate solubility characteristics in organic solvents.

Prop-2-ynyl (2R)-2-[4-[(5-chloro-3-fluoro-2-pyridinyl)oxy]phenoxy]propanoate is primarily used as a chemical intermediate in pharmaceutical and agrochemical synthesis. Its complex structure containing halogenated pyridine and phenoxy groups makes it valuable for developing biologically active compounds. The substance serves as a building block in organic synthesis processes and may be utilized in research and development applications within the chemical industry for creating specialized compounds with specific biological or chemical properties.

Prop-2-ynyl (2R)-2-[4-[(5-chloro-3-fluoro-2-pyridinyl)oxy]phenoxy]propanoate requires careful handling due to its Acute Tox. 4, STOT RE 2, and Skin Sens. 1 classifications. Essential protective equipment includes chemical-resistant gloves, safety goggles, and protective clothing. Work in well-ventilated areas or under fume hoods to prevent inhalation. Avoid skin contact and ensure proper hygiene practices. The substance carries GHS07, GHS08, and GHS09 pictograms indicating health and environmental hazards.

Prop-2-ynyl (2R)-2-[4-[(5-chloro-3-fluoro-2-pyridinyl)oxy]phenoxy]propanoate should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Given its environmental hazard classification (Aquatic Acute 1, Aquatic Chronic 1), prevent release to the environment and store away from water sources. Keep containers properly labeled and store separately from incompatible materials. Ensure storage areas have appropriate spill containment measures and restrict access to authorized personnel only.

Prop-2-ynyl (2R)-2-[4-[(5-chloro-3-fluoro-2-pyridinyl)oxy]phenoxy]propanoate exposure requires immediate action due to its toxicity and skin sensitization properties. For skin contact, immediately remove contaminated clothing and wash thoroughly with soap and water for at least 15 minutes. If inhaled, move to fresh air immediately. For eye contact, flush with clean water for at least 15 minutes. Seek medical attention promptly, especially given the STOT RE 2 classification. Never induce vomiting if swallowed and contact emergency services immediately.

Prop-2-ynyl (2R)-2-[4-[(5-chloro-3-fluoro-2-pyridinyl)oxy]phenoxy]propanoate must be disposed of through authorized hazardous waste disposal facilities due to its environmental and health hazard classifications. The substance cannot be disposed of in regular waste streams given its Aquatic Acute 1 and Aquatic Chronic 1 classifications. Contact licensed waste management companies specialized in chemical waste disposal. Follow all local, national, and EU waste regulations. Ensure proper documentation and waste tracking throughout the disposal process to maintain regulatory compliance.

Prop-2-ynyl (2R)-2-[4-[(5-chloro-3-fluoro-2-pyridinyl)oxy]phenoxy]propanoate is classified as ADR Class 9 (Miscellaneous dangerous goods), Packing Group III for transportation purposes. This classification requires appropriate dangerous goods documentation, proper packaging according to ADR regulations, and transport by qualified carriers. Packages must display correct hazard labels and proper shipping names. Vehicles must carry appropriate emergency response information and drivers must hold valid dangerous goods transport certificates. Ensure compliance with all ADR requirements for Class 9 substances.

Prop-2-ynyl (2R)-2-[4-[(5-chloro-3-fluoro-2-pyridinyl)oxy]phenoxy]propanoate is subject to EU REACH and CLP regulations due to its hazard classifications. The substance is not currently listed as an SVHC (Substance of Very High Concern). Suppliers must provide Safety Data Sheets and ensure proper classification and labeling according to CLP. Users must comply with occupational exposure limits and environmental protection requirements. The compound may also be subject to specific national regulations regarding handling, use, and disposal of hazardous chemicals.

Prop-2-ynyl (2R)-2-[4-[(5-chloro-3-fluoro-2-pyridinyl)oxy]phenoxy]propanoate is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides this substance to qualified industrial and research customers with appropriate expertise in handling hazardous chemicals. Given the substance's classification as Acute Tox. 4 and other hazard categories, purchases are typically restricted to professional users with proper safety infrastructure. Contact OYSI directly for availability, technical specifications, and regulatory documentation required for safe handling and use.