1,2,4,5-tetrachloro-3-nitrobenzene

1,2,4,5-tetrachloro-3-nitrobenzene is an organochlorine compound with the molecular formula C6HCl4NO2 and CAS number 117-18-0. This chemical substance belongs to the family of chlorinated nitroaromatic compounds, featuring a benzene ring substituted with four chlorine atoms and one nitro group. With a molecular weight of 260.9 g/mol, it is classified as hazardous with acute toxicity, skin sensitization, and aquatic toxicity properties under GHS classification.

1,2,4,5-tetrachloro-3-nitrobenzene is typically a solid crystalline substance at room temperature due to its high degree of chlorination and nitro substitution. The compound exhibits limited water solubility due to its hydrophobic chlorinated aromatic structure, but shows better solubility in organic solvents. Its molecular weight of 260.9 g/mol and highly substituted benzene ring contribute to its stability and relatively high melting point compared to less substituted analogues.

1,2,4,5-tetrachloro-3-nitrobenzene is primarily used as an intermediate in organic synthesis and chemical manufacturing processes. It serves as a precursor for the production of other chlorinated aromatic compounds, pharmaceuticals, and specialty chemicals. The compound may also find applications in research and development activities within the chemical industry, particularly in the synthesis of complex organic molecules requiring specific chlorination patterns and nitro functionality.

Safe handling of 1,2,4,5-tetrachloro-3-nitrobenzene requires appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing due to its Acute Tox. 4 and Skin Sens. 1 classifications. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation. Avoid direct skin contact and ensure proper hygiene measures. The substance carries GHS07 and GHS09 pictograms, indicating health and environmental hazards requiring careful handling protocols.

1,2,4,5-tetrachloro-3-nitrobenzene should be stored in tightly sealed containers in a cool, dry, and well-ventilated area away from heat sources and incompatible materials. Given its environmental hazard classification (Aquatic Acute 1, Aquatic Chronic 1), storage areas must have appropriate containment measures to prevent environmental release. Keep containers properly labeled and store separately from oxidizing agents, strong bases, and reducing agents to prevent unwanted reactions.

Immediate action is required in case of contact with 1,2,4,5-tetrachloro-3-nitrobenzene due to its acute toxicity and skin sensitization properties. For skin contact, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. In case of eye contact, flush with clean water for 15 minutes. If inhaled, move to fresh air immediately. Seek medical attention if symptoms develop or persist after exposure.

Disposal of 1,2,4,5-tetrachloro-3-nitrobenzene must comply with local and European waste regulations due to its hazardous classification. The substance requires disposal as hazardous waste through licensed waste management facilities capable of handling chlorinated organic compounds. Incineration at high temperatures in specialized facilities is typically the preferred method. Never dispose of this material in regular waste streams or discharge into sewers due to its aquatic toxicity classification.

Transportation of 1,2,4,5-tetrachloro-3-nitrobenzene is regulated under ADR classification as Class 9 (Miscellaneous dangerous substances), Packing Group III. This classification requires appropriate packaging, labeling, and documentation for road transport. Containers must be properly secured and labeled with the correct hazard markings. Transport vehicles should carry appropriate emergency equipment, and drivers must be trained in hazardous materials handling procedures according to ADR regulations.

1,2,4,5-tetrachloro-3-nitrobenzene is subject to various European chemical regulations including REACH registration requirements and CLP classification. While not currently listed as an SVHC (Substance of Very High Concern), it must comply with standard chemical safety requirements. The substance falls under hazardous chemical regulations due to its acute toxicity, skin sensitization, and environmental hazard classifications, requiring appropriate risk management measures and safety data sheet provision.

1,2,4,5-tetrachloro-3-nitrobenzene is available through OYSI, a specialized European distributor of technical chemicals. As a professional chemical supplier, OYSI can provide this substance with appropriate documentation, safety data sheets, and regulatory compliance support. Contact OYSI directly for availability, specifications, and technical support for your specific application requirements. Professional handling and regulatory expertise ensure safe and compliant supply of this hazardous substance.