(1R)-1-[(2R,3aR,5R,6S,6aR)-6-hydroxy-2-(trichloromethyl)-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-5-yl]ethane-1,2-diol

(1R)-1-[(2R,3aR,5R,6S,6aR)-6-hydroxy-2-(trichloromethyl)-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-5-yl]ethane-1,2-diol is an organic chemical compound with CAS number 15879-93-3 and molecular formula C8H11Cl3O6. This complex molecule features a furodioxol ring system with multiple hydroxyl groups and a trichloromethyl substituent. With a molecular weight of 309.5 g/mol, it presents significant toxicological hazards and environmental concerns, classified under multiple danger categories including acute toxicity and aquatic toxicity.

(1R)-1-[(2R,3aR,5R,6S,6aR)-6-hydroxy-2-(trichloromethyl)-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-5-yl]ethane-1,2-diol has a molecular weight of 309.5 g/mol with the formula C8H11Cl3O6. The compound contains multiple polar hydroxyl groups and a highly electronegative trichloromethyl group, which significantly influence its physical properties. The presence of three chlorine atoms and several oxygen-containing functional groups affects its polarity, solubility characteristics, and chemical reactivity. Specific physical data such as melting point, boiling point, and exact solubility parameters would require detailed analytical characterization.

(1R)-1-[(2R,3aR,5R,6S,6aR)-6-hydroxy-2-(trichloromethyl)-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-5-yl]ethane-1,2-diol serves as a specialized chemical intermediate in pharmaceutical and fine chemical synthesis. Its unique stereochemistry and functional group arrangement make it valuable for advanced organic synthesis applications. The compound's complex structure with multiple chiral centers suggests potential use in the development of bioactive molecules or as a building block for more complex pharmaceutical compounds. Due to its significant toxicological profile, its use is restricted to professional industrial applications with appropriate safety controls.

(1R)-1-[(2R,3aR,5R,6S,6aR)-6-hydroxy-2-(trichloromethyl)-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-5-yl]ethane-1,2-diol requires strict safety measures due to its Acute Tox. 3 and 4 classifications. Essential PPE includes chemical-resistant gloves, safety goggles, and respiratory protection in well-ventilated areas. Work only in fume hoods to prevent inhalation exposure. Avoid skin and eye contact completely. Emergency shower and eyewash stations must be readily accessible. All personnel must be trained in hazardous material handling procedures before use.

(1R)-1-[(2R,3aR,5R,6S,6aR)-6-hydroxy-2-(trichloromethyl)-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-5-yl]ethane-1,2-diol must be stored in a secure, cool, dry, well-ventilated area away from heat sources and incompatible materials. Use tightly sealed, chemically compatible containers to prevent contamination and vapor release. Store separately from oxidizing agents, bases, and reactive metals due to the trichloromethyl group's reactivity. Implement restricted access controls due to its acute toxicity classification. Maintain detailed inventory records and ensure proper labeling with GHS06 and GHS09 pictograms.

Immediate action is critical following contact with (1R)-1-[(2R,3aR,5R,6S,6aR)-6-hydroxy-2-(trichloromethyl)-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-5-yl]ethane-1,2-diol due to its acute toxicity. For skin contact, immediately remove contaminated clothing and wash with copious amounts of water for at least 15 minutes. For eye contact, flush continuously with water and seek immediate medical attention. If inhaled, move to fresh air immediately. Never induce vomiting if swallowed. Contact poison control and seek immediate professional medical assistance in all cases, providing the safety data sheet to medical personnel.

(1R)-1-[(2R,3aR,5R,6S,6aR)-6-hydroxy-2-(trichloromethyl)-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-5-yl]ethane-1,2-diol requires disposal as hazardous waste through licensed disposal facilities due to its acute toxicity and environmental hazard classifications. Never dispose of via regular waste streams or sewers due to its Aquatic Acute 1 and Aquatic Chronic 1 classifications. Contact certified hazardous waste disposal companies for proper collection and treatment. Maintain detailed disposal documentation for regulatory compliance. Small laboratory quantities may require incineration at high temperatures with appropriate emission controls.

(1R)-1-[(2R,3aR,5R,6S,6aR)-6-hydroxy-2-(trichloromethyl)-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-5-yl]ethane-1,2-diol is classified as ADR Class 6.1, Packing Group III for transport of toxic substances. Packages must comply with UN packaging requirements for toxic materials, including proper labeling with Class 6.1 dangerous goods labels. Transport documentation must include proper shipping names and hazard classifications. Drivers require ADR training certification for Class 6.1 materials. Emergency response information and safety data sheets must accompany all shipments.

(1R)-1-[(2R,3aR,5R,6S,6aR)-6-hydroxy-2-(trichloromethyl)-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-5-yl]ethane-1,2-diol is subject to multiple European regulations including REACH registration requirements and CLP classification obligations. The compound is not currently listed as a SVHC but must comply with ADR transport regulations as Class 6.1 material. Its acute toxicity and environmental hazard classifications trigger specific labeling, packaging, and handling requirements. Users must implement appropriate risk management measures and maintain safety data sheets. Professional users should verify current regulatory status as requirements may evolve.

(1R)-1-[(2R,3aR,5R,6S,6aR)-6-hydroxy-2-(trichloromethyl)-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-5-yl]ethane-1,2-diol is available through OYSI, a specialized European distributor of fine chemicals and pharmaceutical intermediates. OYSI provides comprehensive technical support, regulatory documentation, and ensures full compliance with European chemical regulations. As a trusted supplier network across Europe, OYSI maintains high quality standards and proper handling procedures for hazardous materials. Contact OYSI directly for availability, technical specifications, and regulatory compliance documentation required for your specific application.