4-[2-(4-tert-butylphenyl)ethoxy]quinazoline

4-[2-(4-tert-butylphenyl)ethoxy]quinazoline is a synthetic organic compound with the molecular formula C20H22N2O and a molecular weight of 306.4 g/mol. This quinazoline derivative features a tert-butylphenyl group connected via an ethoxy linker to the quinazoline core structure. It is classified as a hazardous substance with acute toxicity properties and environmental concerns. The compound is identified by CAS number 120928-09-8 and requires careful handling due to its toxic nature.

4-[2-(4-tert-butylphenyl)ethoxy]quinazoline is an organic solid compound with a molecular weight of 306.4 g/mol and formula C20H22N2O. The compound contains aromatic quinazoline and phenyl ring systems connected by an ethoxy bridge, conferring specific solubility characteristics. Due to its aromatic nature and molecular structure, it likely exhibits limited water solubility but good solubility in organic solvents. Specific physical properties such as melting point, boiling point, and exact appearance require experimental determination.

4-[2-(4-tert-butylphenyl)ethoxy]quinazoline is primarily used as a research chemical and pharmaceutical intermediate in specialized applications. The quinazoline scaffold is commonly found in bioactive molecules and pharmaceutical compounds, suggesting potential use in drug discovery and medicinal chemistry research. Its specific applications may include synthesis of more complex molecules, biological activity studies, or as a building block in pharmaceutical development. Industrial uses are typically limited to specialized chemical manufacturing and research institutions.

4-[2-(4-tert-butylphenyl)ethoxy]quinazoline requires careful handling due to its Acute Tox. 4 and Acute Tox. 3 classifications with GHS06 pictogram indicating danger. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and laboratory coat. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid direct skin and eye contact, and never eat, drink, or smoke while handling. Wash hands thoroughly after use and ensure proper training before handling this toxic substance.

4-[2-(4-tert-butylphenyl)ethoxy]quinazoline should be stored in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Keep containers tightly closed and properly labeled with hazard information including GHS06 and GHS09 pictograms. Store separately from food, beverages, and feed materials. Due to its toxic and environmentally hazardous nature, implement appropriate containment measures to prevent accidental release. Access should be restricted to trained personnel, and storage areas should comply with local chemical storage regulations.

Immediate action is required due to the acute toxicity of 4-[2-(4-tert-butylphenyl)ethoxy]quinazoline. For skin contact: remove contaminated clothing and wash affected area with plenty of water for at least 15 minutes. Eye contact: rinse immediately with water for 15 minutes, holding eyelids open. Inhalation: move to fresh air immediately. Ingestion: do not induce vomiting, rinse mouth with water. Seek medical attention immediately in all cases and provide the safety data sheet to medical personnel for proper treatment guidance.

4-[2-(4-tert-butylphenyl)ethoxy]quinazoline must be disposed of as hazardous waste due to its toxic and environmentally hazardous classification (Aquatic Acute 1, Aquatic Chronic 1). Contact licensed hazardous waste disposal companies for proper treatment and disposal. Never discharge into sewers, waterways, or soil due to severe environmental impact. Small laboratory quantities should be collected in appropriate containers and labeled for hazardous waste pickup. Follow local, national, and European waste disposal regulations, including proper documentation and manifesting procedures.

4-[2-(4-tert-butylphenyl)ethoxy]quinazoline is classified under ADR Class 6.1 (Toxic substances) Packing Group III, requiring compliance with dangerous goods transportation regulations. Use appropriate UN-specification packaging designed for Class 6.1 materials. Packages must display proper hazard labels, UN identification numbers, and shipping documentation. Transportation should be handled by trained personnel familiar with dangerous goods regulations. Ensure vehicles are properly placarded and equipped with appropriate emergency response information. Follow European ADR regulations for road transport and corresponding modal regulations for other transport methods.

4-[2-(4-tert-butylphenyl)ethoxy]quinazoline is subject to multiple European chemical regulations including REACH registration requirements and CLP hazard classification and labeling. It is not currently listed as a Substance of Very High Concern (SVHC). The substance requires hazard communication through safety data sheets, proper labeling with GHS pictograms (GHS06, GHS09), and the danger signal word. Companies must comply with occupational exposure limits, environmental protection measures, and transportation regulations under ADR Class 6.1 classification.

4-[2-(4-tert-butylphenyl)ethoxy]quinazoline is available through OYSI, a specialized European distributor of technical chemicals serving the research and industrial markets. OYSI provides this compound with proper regulatory compliance, including safety data sheets, hazard labeling, and appropriate packaging for safe handling and transport. As a professional chemical distributor, OYSI ensures product quality and regulatory compliance with European chemical legislation. Contact OYSI directly for availability, technical specifications, and ordering information for this specialized quinazoline derivative compound.