4-[2-(4-tert-butylphenyl)ethoxy]quinazoline

4-[2-(4-tert-butylphenyl)ethoxy]quinazoline is an organic compound with the molecular formula C20H22N2O and a molecular weight of 306.4 g/mol. This quinazoline derivative contains a tert-butylphenyl group connected via an ethoxy linker to the quinazoline core structure. It is classified as a hazardous substance with acute toxicity properties and environmental concerns, requiring careful handling in professional applications.

4-[2-(4-tert-butylphenyl)ethoxy]quinazoline has a molecular mass of 306.4 g/mol with the formula C20H22N2O. As a quinazoline derivative, it typically appears as a solid at room temperature. The compound contains both aromatic systems and an ether linkage, which influences its solubility characteristics. Specific physical properties such as melting point, color, and solubility data should be confirmed through technical documentation from suppliers.

4-[2-(4-tert-butylphenyl)ethoxy]quinazoline is primarily used as a research chemical and pharmaceutical intermediate. Its quinazoline structure makes it valuable in medicinal chemistry research and drug development processes. The compound may serve as a building block for synthesizing more complex pharmaceutical compounds or as a reference standard in analytical applications. Its specific applications depend on the research objectives and synthetic pathways being investigated.

4-[2-(4-tert-butylphenyl)ethoxy]quinazoline requires careful handling due to its Acute Tox. 4 and Acute Tox. 3 classifications. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and appropriate respiratory protection when necessary. Work should be conducted in well-ventilated areas or under fume hoods. Avoid skin contact, inhalation, and ingestion. The GHS06 pictogram indicates acute toxicity hazards, requiring strict adherence to safety protocols during handling and use.

4-[2-(4-tert-butylphenyl)ethoxy]quinazoline should be stored in a cool, dry place away from incompatible materials and sources of ignition. As a toxic substance, it must be kept in secure, labeled containers in restricted access areas. Storage areas should be well-ventilated and equipped with appropriate containment measures. Consider environmental protection requirements due to its Aquatic Acute 1 and Aquatic Chronic 1 classifications. Regular inventory checks and proper labeling are essential for safe storage management.

Immediate action is required following contact with 4-[2-(4-tert-butylphenyl)ethoxy]quinazoline due to its acute toxicity. For skin contact, remove contaminated clothing and wash thoroughly with soap and water. In case of eye contact, flush immediately with clean water for at least 15 minutes. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical attention. Always consult the safety data sheet for specific first aid measures and contact emergency services when necessary.

4-[2-(4-tert-butylphenyl)ethoxy]quinazoline must be disposed of as hazardous waste through licensed waste management companies. Due to its acute toxicity and environmental hazard classifications (Aquatic Acute 1, Aquatic Chronic 1), it cannot be released into water systems or regular waste streams. Disposal must comply with local, national, and EU waste regulations. Containers should be properly labeled and segregated according to waste classification requirements before collection by authorized waste handlers.

4-[2-(4-tert-butylphenyl)ethoxy]quinazoline is classified under ADR Class 6.1 (toxic substances), Packing Group III for transportation purposes. This classification requires specific packaging, labeling, and documentation according to dangerous goods regulations. Transport vehicles must be properly placarded, and drivers require appropriate dangerous goods training. Shipping documentation must include proper shipping names, hazard labels, and emergency response information. Only authorized carriers experienced in handling Class 6.1 materials should transport this substance.

4-[2-(4-tert-butylphenyl)ethoxy]quinazoline is subject to standard EU chemical regulations including REACH and CLP classifications. It carries GHS pictograms GHS06 and GHS09 with the signal word 'Danger', indicating acute toxicity and environmental hazards. The substance is not currently listed as a Substance of Very High Concern (SVHC). Users must comply with occupational safety regulations, environmental protection laws, and proper classification, labeling, and packaging requirements under CLP regulation.

4-[2-(4-tert-butylphenyl)ethoxy]quinazoline is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides this compound with proper documentation, safety data sheets, and regulatory compliance support for professional users. As a technical chemical requiring specialized handling, it is typically supplied to research institutions, pharmaceutical companies, and qualified industrial users. Contact OYSI directly for availability, specifications, and technical support for your specific application requirements.