1,2,3,4,5,6-hexachlorocyclohexane

C6H6Cl6

CAS58-89-9
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Danger

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Identification

CAS Number
58-89-9
EC Number
200-401-2
UN Number
2761
Index Number
602-043-00-6
PubChem CID
727

Physical-chemical properties

Molecular Formula
C6H6Cl6
Molar Mass
290.80 g/mol
IUPAC Name
1,2,3,4,5,6-hexachlorocyclohexane

Chemical Identifiers

InChI
InChI=1S/C6H6Cl6/c7-1-2(8)4(10)6(12)5(11)3(1)9/h1-6H
InChI Key
JLYXXMFPNIAWKQ-UHFFFAOYSA-N

Overview

1,2,3,4,5,6-hexachlorocyclohexane (CAS 58-89-9) is a chlorinated cyclic hydrocarbon compound characterized by its high chlorine content and significant environmental persistence. This organochlorine compound, commonly known by its CAS number 58-89-9, represents a fully chlorinated derivative of cyclohexane where all six hydrogen atoms have been substituted with chlorine atoms. With a molecular formula of C6H6Cl6 and molecular weight of 290.8 g/mol, hexachlorocyclohexane exhibits the typical properties of heavily halogenated hydrocarbons, including high chemical stability and low biodegradability. The compound presents significant safety considerations, classified under multiple hazard categories including acute toxicity through various exposure routes and specific target organ toxicity following repeated exposure. Its classification under GHS pictograms GHS06, GHS08, and GHS09 indicates serious health hazards and severe environmental risks, particularly regarding aquatic ecosystems where it demonstrates both acute and chronic toxicity. The ADR Class 6.1 designation confirms its status as a toxic substance requiring specialized handling and transport protocols. From a chemical perspective, hexachlorocyclohexane shares structural similarities with other chlorinated compounds, though it differs significantly from simpler aromatic compounds such as N-methylaniline in terms of toxicity profile and environmental behavior. Its high degree of chlorination results in exceptional chemical inertness under normal conditions, making it resistant to most degradation processes. Industrial applications primarily focus on specialized chemical synthesis processes where its unique chlorination pattern provides specific reactivity characteristics. The compound also finds limited use in research applications and as an intermediate in the production of other chlorinated derivatives. OYSI maintains availability of 1,2,3,4,5,6-hexachlorocyclohexane for qualified industrial customers with appropriate handling capabilities and regulatory compliance frameworks.

Safety & Classification

Danger
Classification:

Lact.; Acute Tox. 4 *; Acute Tox. 4 *; Acute Tox. 3 *; STOT RE 2 *; Aquatic Acute 1; Aquatic Chro...

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H362

May cause harm to breast-fed children.

H332

Harmful if inhaled.

H312

Harmful in contact with skin.

H301

Toxic if swallowed.

H373

May cause damage to organs through prolonged or repeated exposure.

H400

Very toxic to aquatic life.

H410

Very toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Harmful

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Toxic

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2761
ADR Class6.1
Packing GroupIII
Tunnel CodeE
Proper Shipping NameLindan (ISO)
Marine PollutantNo

Frequently Asked Questions

What is 1,2,3,4,5,6-hexachlorocyclohexane?

1,2,3,4,5,6-hexachlorocyclohexane is an organochlorine compound with the molecular formula C6H6Cl6 and CAS number 58-89-9. This chemical substance has a molecular weight of 290.8 g/mol and consists of a cyclohexane ring where all six hydrogen atoms are replaced by chlorine atoms. It is classified as a hazardous substance requiring careful handling due to its toxic properties and environmental persistence.

What are the physicochemical properties of 1,2,3,4,5,6-hexachlorocyclohexane?

1,2,3,4,5,6-hexachlorocyclohexane is a solid organochlorine compound at room temperature with high stability due to its saturated chlorinated structure. The substance exhibits low water solubility but dissolves well in organic solvents. Its high chlorine content contributes to its persistence in the environment and bioaccumulation potential, making it a substance of concern for ecological safety.

What is 1,2,3,4,5,6-hexachlorocyclohexane used for?

1,2,3,4,5,6-hexachlorocyclohexane serves primarily as an intermediate in chemical synthesis and research applications. Due to its highly regulated status and environmental concerns, its commercial applications are severely restricted. The substance may be used in specialized laboratory research, analytical chemistry, or as a reference standard. Industrial use is limited due to strict regulatory controls governing organochlorine compounds.

How to handle 1,2,3,4,5,6-hexachlorocyclohexane safely?

1,2,3,4,5,6-hexachlorocyclohexane requires strict safety protocols including appropriate personal protective equipment such as chemical-resistant gloves, safety goggles, and respiratory protection. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. The substance's classification as Acute Tox. 3-4 and STOT RE 2 demands careful handling to avoid skin contact, ingestion, or inhalation of vapors or dust.

How to store 1,2,3,4,5,6-hexachlorocyclohexane correctly?

1,2,3,4,5,6-hexachlorocyclohexane must be stored in tightly sealed containers in a cool, dry, well-ventilated area away from incompatible materials. Storage areas should be secure and accessible only to trained personnel due to the substance's toxic properties. Containers should be properly labeled according to GHS requirements, displaying appropriate pictogrammes (GHS06, GHS08, GHS09) and the 'Danger' signal word to ensure proper identification and handling.

What to do in case of contact with 1,2,3,4,5,6-hexachlorocyclohexane?

Immediate action is required upon contact with 1,2,3,4,5,6-hexachlorocyclohexane due to its acute toxicity classification. For skin contact, remove contaminated clothing and wash thoroughly with soap and water. In case of eye contact, flush immediately with plenty of water for at least 15 minutes. If inhaled, move to fresh air immediately. Seek medical attention promptly for any exposure, providing the safety data sheet to medical personnel.

How to dispose of 1,2,3,4,5,6-hexachlorocyclohexane appropriately?

1,2,3,4,5,6-hexachlorocyclohexane disposal must comply with strict hazardous waste regulations due to its environmental persistence and toxicity. The substance requires disposal through licensed hazardous waste contractors capable of handling organochlorine compounds. Incineration at high temperatures in specialized facilities is typically required. Never dispose of this substance through regular waste streams or sewage systems due to its Aquatic Acute 1 classification and environmental impact.

How to transport 1,2,3,4,5,6-hexachlorocyclohexane?

1,2,3,4,5,6-hexachlorocyclohexane is classified under ADR as Class 6.1 (toxic substances), Packing Group III for transportation purposes. Proper shipping names, hazard labels, and documentation must accompany shipments according to dangerous goods regulations. Packages must meet UN specification requirements and display appropriate hazard markings. Transportation should only be handled by carriers certified for dangerous goods transport with proper emergency response capabilities.

Is 1,2,3,4,5,6-hexachlorocyclohexane subject to specific regulations?

1,2,3,4,5,6-hexachlorocyclohexane is subject to extensive regulatory oversight under REACH, CLP, and various environmental protection laws. While not currently listed as an SVHC, its classification under multiple hazard categories requires compliance with strict registration, notification, and safety requirements. The substance may be subject to restrictions or authorization requirements depending on intended use and quantities, requiring careful regulatory assessment before purchase or use.

Where to buy 1,2,3,4,5,6-hexachlorocyclohexane in Europe?

1,2,3,4,5,6-hexachlorocyclohexane is available through OYSI, a specialized European distributor of chemical products with expertise in handling regulated substances. Due to the strict regulatory requirements and hazardous nature of this compound, procurement requires proper documentation, intended use justification, and compliance verification. OYSI provides technical support and ensures regulatory compliance for customers requiring this specialized chemical compound throughout Europe.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.