1,2,3,4,5,6-hexachlorocyclohexane

C6H6Cl6

CAS58-89-9
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Danger

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Identification

CAS Number
58-89-9
EC Number
200-401-2
UN Number
2761
Index Number
602-043-00-6
PubChem CID
727

Physical-chemical properties

Molecular Formula
C6H6Cl6
Molar Mass
290.80 g/mol
IUPAC Name
1,2,3,4,5,6-hexachlorocyclohexane

Chemical Identifiers

InChI
InChI=1S/C6H6Cl6/c7-1-2(8)4(10)6(12)5(11)3(1)9/h1-6H
InChI Key
JLYXXMFPNIAWKQ-UHFFFAOYSA-N

Overview

1,2,3,4,5,6-hexachlorocyclohexane (CAS 608-73-1) is a chlorinated cyclic hydrocarbon with significant industrial applications and notable environmental persistence. This organochlorine compound, also known by its EC number 210-168-9, represents a fully chlorinated derivative of cyclohexane with the molecular formula C6H6Cl6 and a molecular weight of 290.8 g/mol. As a member of the hexachlorocyclohexane family, this substance exhibits the characteristic properties of persistent organic compounds, making it both valuable for specific industrial applications and requiring careful handling protocols. The compound presents significant safety considerations, classified under multiple hazard categories including suspected carcinogenicity (Carc. 2), acute toxicity (Acute Tox. 3 and 4), and severe aquatic toxicity (Aquatic Acute 1, Aquatic Chronic 1). These classifications necessitate the "Danger" signal word and corresponding GHS pictograms (GHS08, GHS06, GHS09), indicating serious health hazards, toxicity, and environmental dangers. Transportation falls under ADR Class 6.1, reflecting its toxic nature during handling and shipment. Unlike simpler aromatic compounds such as N-methylaniline, hexachlorocyclohexane's extensive chlorination provides enhanced chemical stability and specific reactivity patterns. This stability makes it particularly suitable for applications requiring persistent chemical intermediates, specialty chemical synthesis, and research applications in organic chemistry laboratories. The compound also finds use in the production of specialized pesticide formulations where its chlorinated structure provides desired biological activity. Industrial applications primarily focus on its role as a chemical intermediate in pharmaceutical synthesis, specialty polymer production, and as a research standard in analytical chemistry applications. OYSI maintains reliable supply chains for 1,2,3,4,5,6-hexachlorocyclohexane, ensuring consistent availability for qualified industrial customers across European markets.

Safety & Classification

Danger
Classification:

Lact.; Acute Tox. 4 *; Acute Tox. 4 *; Acute Tox. 3 *; STOT RE 2 *; Aquatic Acute 1; Aquatic Chro...

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H362

May cause harm to breast-fed children.

H332

Harmful if inhaled.

H312

Harmful in contact with skin.

H301

Toxic if swallowed.

H373

May cause damage to organs through prolonged or repeated exposure.

H400

Very toxic to aquatic life.

H410

Very toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Harmful

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Toxic

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2761
ADR Class6.1
Packing GroupIII
Tunnel CodeE
Proper Shipping NameLindan (ISO)
Marine PollutantNo

Frequently Asked Questions

What is 1,2,3,4,5,6-hexachlorocyclohexane?

1,2,3,4,5,6-hexachlorocyclohexane is an organochlorine compound with the molecular formula C6H6Cl6 and CAS number 608-73-1. This chemical consists of a cyclohexane ring where all six hydrogen atoms are replaced by chlorine atoms, resulting in a molecular weight of 290.8 g/mol. It is classified as a hazardous substance with carcinogenic properties and high toxicity to aquatic environments.

What are the physicochemical properties of 1,2,3,4,5,6-hexachlorocyclohexane?

1,2,3,4,5,6-hexachlorocyclohexane is a solid organochlorine compound at room temperature with high chlorine content. As a heavily chlorinated cyclohexane derivative, it exhibits low water solubility due to its hydrophobic nature. The compound is chemically stable under normal conditions but may decompose under extreme heat, releasing toxic chlorinated compounds. Its high molecular weight and chlorine substitution pattern influence its environmental persistence and bioaccumulation potential.

What is 1,2,3,4,5,6-hexachlorocyclohexane used for?

1,2,3,4,5,6-hexachlorocyclohexane is primarily used as a chemical intermediate in specialized industrial synthesis processes. Due to its hazardous classification and environmental concerns, its applications are strictly limited to professional industrial settings with appropriate safety controls. The compound may serve as a precursor in the production of other chlorinated chemicals or as a research standard in analytical laboratories for environmental monitoring and contamination studies.

How to handle 1,2,3,4,5,6-hexachlorocyclohexane safely?

1,2,3,4,5,6-hexachlorocyclohexane requires strict safety protocols due to its carcinogenic and toxic properties. Personnel must wear appropriate PPE including chemical-resistant gloves, protective clothing, and respiratory protection. Work should be conducted in well-ventilated areas or under fume extraction systems. Avoid skin and eye contact, inhalation, and ingestion. Only trained personnel should handle this substance, following established safety procedures and emergency response protocols.

How to store 1,2,3,4,5,6-hexachlorocyclohexane correctly?

1,2,3,4,5,6-hexachlorocyclohexane must be stored in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Use tightly sealed, chemically compatible containers to prevent contamination and release. Storage areas should be equipped with appropriate containment systems and restricted to authorized personnel only. Regular inspection of containers for signs of deterioration or leakage is essential. Maintain inventory records and ensure compliance with local storage regulations.

What to do in case of contact with 1,2,3,4,5,6-hexachlorocyclohexane?

Immediate action is required upon contact with 1,2,3,4,5,6-hexachlorocyclohexane. For skin contact, remove contaminated clothing and flush affected area with plenty of water for at least 15 minutes. In case of eye contact, rinse thoroughly with water and seek immediate medical attention. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek emergency medical care. Always consult a physician and provide the safety data sheet.

How to dispose of 1,2,3,4,5,6-hexachlorocyclohexane appropriately?

1,2,3,4,5,6-hexachlorocyclohexane must be disposed of as hazardous waste through licensed waste management facilities specialized in handling toxic and carcinogenic substances. Never dispose of this chemical in regular waste streams, drains, or soil. Contact certified hazardous waste disposal companies for proper collection and treatment. Maintain detailed disposal records as required by environmental regulations. Small quantities may require special incineration at high temperatures under controlled conditions.

How to transport 1,2,3,4,5,6-hexachlorocyclohexane?

1,2,3,4,5,6-hexachlorocyclohexane is classified under ADR as Class 6.1 (toxic substances), Packing Group III. Transportation requires appropriate UN-specification packaging, proper labeling with GHS pictogrammes (GHS06, GHS08, GHS09), and transport documentation. Only authorized carriers experienced in handling toxic chemicals should transport this substance. Vehicles must be equipped with appropriate emergency equipment and drivers must hold valid ADR certificates for dangerous goods transport.

Is 1,2,3,4,5,6-hexachlorocyclohexane subject to specific regulations?

1,2,3,4,5,6-hexachlorocyclohexane is subject to strict European regulations under REACH and CLP due to its hazardous properties. The substance requires proper registration, classification as Carcinogenic Category 2, and compliance with occupational exposure limits. Special restrictions may apply for its use and marketing. Companies handling this chemical must implement risk management measures, provide safety data sheets, and ensure worker protection according to occupational health regulations.

Where to buy 1,2,3,4,5,6-hexachlorocyclohexane in Europe?

1,2,3,4,5,6-hexachlorocyclohexane is available through OYSI, a specialized European distributor of technical chemicals. As a professional chemical supplier, OYSI provides this substance to qualified industrial customers with appropriate handling capabilities and regulatory compliance. Purchase requires verification of intended use and safety management systems due to the substance's hazardous classification. Contact OYSI directly for availability, specifications, and regulatory documentation required for your specific application.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.