(4-chlorophenyl) 4-chlorobenzenesulfonate

C12H8Cl2O3S

CAS80-33-1
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
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Identification

CAS Number
80-33-1
EC Number
201-270-4
UN Number
3077
Index Number
607-156-00-4
PubChem CID
6635

Physical-chemical properties

Molecular Formula
C12H8Cl2O3S
Molar Mass
303.20 g/mol
IUPAC Name
(4-chlorophenyl) 4-chlorobenzenesulfonate

Chemical Identifiers

InChI
InChI=1S/C12H8Cl2O3S/c13-9-1-5-11(6-2-9)17-18(15,16)12-7-3-10(14)4-8-12/h1-8H
InChI Key
RZXLPPRPEOUENN-UHFFFAOYSA-N

Overview

(4-chlorophenyl) 4-chlorobenzenesulfonate (CAS 80-33-1) is an organosulfonate ester compound with dual chlorinated aromatic rings and moderate acute toxicity properties. This specialized chemical compound belongs to the family of chlorinated aromatic sulfonates, featuring a distinctive molecular structure with two chlorine-substituted benzene rings connected through a sulfonate ester linkage. With its molecular formula C12H8Cl2O3S and molecular weight of 303.2 g/mol, this substance exhibits unique physicochemical properties that make it valuable for specific industrial applications requiring chlorinated aromatic compounds. The compound presents moderate safety considerations, classified under GHS hazard categories including Acute Toxicity 4, Skin Irritation 2, and significant aquatic toxicity (both acute and chronic). The Warning signal word and associated GHS07 and GHS09 pictograms indicate the need for appropriate handling procedures to prevent skin contact and environmental release. Its ADR Class 9 classification designates it as a miscellaneous dangerous substance requiring specialized transport protocols. Industrial applications typically include use as a chemical intermediate in organic synthesis, particularly in the production of specialty chemicals where chlorinated aromatic structures are required. The compound also finds application in research and development settings for pharmaceutical intermediate synthesis and in certain polymer chemistry applications. Its structural similarity to compounds like 1,2,4-trichlorobenzene makes it useful in analogous chemical processes requiring chlorinated aromatic systems. OYSI maintains reliable supply chains for (4-chlorophenyl) 4-chlorobenzenesulfonate to support European industrial customers with consistent quality and technical support.

Safety & Classification

Warning
Classification:

Acute Tox. 4 *; Skin Irrit. 2; Aquatic Acute 1; Aquatic Chronic 1

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H302

Harmful if swallowed.

H315

Causes skin irritation.

H400

Very toxic to aquatic life.

H410

Very toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Skin Contact

Irritant

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number3077
ADR Class9
Packing GroupIII
Tunnel Code-
Proper Shipping NameChlorfenson (ISO)
Marine PollutantNo

Frequently Asked Questions

What is (4-chlorophenyl) 4-chlorobenzenesulfonate?

(4-chlorophenyl) 4-chlorobenzenesulfonate is an organic chemical compound with the molecular formula C12H8Cl2O3S and CAS number 80-33-1. This sulfonate ester has a molecular weight of 303.2 g/mol and contains two chlorinated aromatic rings connected through a sulfonate linkage. It is classified as a hazardous substance with acute toxicity, skin irritation properties, and environmental toxicity to aquatic organisms.

What are the physicochemical properties of (4-chlorophenyl) 4-chlorobenzenesulfonate?

(4-chlorophenyl) 4-chlorobenzenesulfonate is a solid organic compound at room temperature with a molecular weight of 303.2 g/mol. The compound features two chlorinated benzene rings connected via a sulfonate ester bond, giving it relatively stable chemical properties. Its dual aromatic structure with electron-withdrawing chlorine substituents influences its solubility characteristics and chemical reactivity in various solvents and reaction conditions.

What is (4-chlorophenyl) 4-chlorobenzenesulfonate used for?

(4-chlorophenyl) 4-chlorobenzenesulfonate serves as a chemical intermediate in organic synthesis and pharmaceutical manufacturing processes. Its sulfonate ester structure makes it valuable in chemical reactions requiring specific reactivity patterns. The compound is typically used in industrial applications where controlled chemical transformations are needed, particularly in processes involving aromatic chemistry and ester functionalization reactions.

How to handle (4-chlorophenyl) 4-chlorobenzenesulfonate safely?

(4-chlorophenyl) 4-chlorobenzenesulfonate requires careful handling due to its Acute Tox. 4 and Skin Irrit. 2 classifications. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and protective clothing to prevent skin contact. Work in well-ventilated areas or use local exhaust ventilation. Avoid inhalation, ingestion, and direct skin contact. Follow GHS07 warning pictogram precautions and maintain good industrial hygiene practices during use.

How to store (4-chlorophenyl) 4-chlorobenzenesulfonate correctly?

(4-chlorophenyl) 4-chlorobenzenesulfonate should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Keep containers properly labeled and segregated according to chemical compatibility guidelines. Store away from strong oxidizers and reducing agents. Maintain storage temperatures within recommended ranges and ensure proper containment to prevent environmental release, given its aquatic toxicity classification.

What to do in case of contact with (4-chlorophenyl) 4-chlorobenzenesulfonate?

Immediate action is required if contact occurs with (4-chlorophenyl) 4-chlorobenzenesulfonate due to its skin irritation and acute toxicity properties. For skin contact, immediately wash with plenty of water for at least 15 minutes and remove contaminated clothing. For eye contact, rinse thoroughly with water. If inhaled, move to fresh air. If ingested, do not induce vomiting and seek immediate medical attention. Always consult the safety data sheet for specific first aid measures.

How to dispose of (4-chlorophenyl) 4-chlorobenzenesulfonate appropriately?

(4-chlorophenyl) 4-chlorobenzenesulfonate must be disposed of as hazardous waste through licensed waste management companies due to its toxicity and environmental impact classifications. Do not discharge to sewers, waterways, or soil given its Aquatic Acute 1 and Aquatic Chronic 1 classifications. Follow local and national regulations for hazardous chemical waste disposal. Incineration at appropriate high-temperature facilities may be suitable under proper regulatory oversight.

How to transport (4-chlorophenyl) 4-chlorobenzenesulfonate?

(4-chlorophenyl) 4-chlorobenzenesulfonate is classified as ADR Class 9 (Miscellaneous dangerous goods), Packing Group III for transportation purposes. This classification requires appropriate packaging, labeling, and documentation according to international dangerous goods regulations. Transport vehicles must comply with ADR requirements including proper placarding and driver certification. Ensure packages are properly sealed, labeled, and accompanied by appropriate transport documentation including safety data sheets.

Is (4-chlorophenyl) 4-chlorobenzenesulfonate subject to specific regulations?

(4-chlorophenyl) 4-chlorobenzenesulfonate is subject to European REACH and CLP regulations due to its hazardous properties but is not currently listed as a Substance of Very High Concern (SVHC). Companies must comply with registration, evaluation, and classification requirements under these frameworks. The compound's acute toxicity and environmental hazard classifications require appropriate risk assessment, safety data sheet provision, and worker protection measures in accordance with occupational health regulations.

Where to buy (4-chlorophenyl) 4-chlorobenzenesulfonate in Europe?

(4-chlorophenyl) 4-chlorobenzenesulfonate is available through OYSI, a specialized European distributor of technical chemical products. OYSI provides this compound with full regulatory compliance including proper classification, labeling, and safety documentation according to European standards. As a professional chemical distributor, OYSI ensures product quality, regulatory compliance, and technical support for industrial customers across Europe requiring this specialized chemical intermediate.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.