1,1-dimethylhydrazine

C2H8N2

CAS57-14-7
GHS02 Gefahrensymbol: Entzündbar – Flamme
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
GHS05 Gefahrensymbol: Ätzend – Ätzwirkung
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Danger

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Identification

CAS Number
57-14-7
EC Number
200-316-0
UN Number
1163
Index Number
007-012-00-5
PubChem CID
5976

Physical-chemical properties

Molecular Formula
C2H8N2
Molar Mass
60.10 g/mol
IUPAC Name
1,1-dimethylhydrazine

Chemical Identifiers

InChI
InChI=1S/C2H8N2/c1-4(2)3/h3H2,1-2H3
InChI Key
RHUYHJGZWVXEHW-UHFFFAOYSA-N

Overview

1,1-dimethylhydrazine (CAS 57-14-7) is a highly toxic organic hydrazine compound with strong reducing properties and significant carcinogenic potential. This colorless to pale yellow liquid represents one of the most hazardous chemicals in industrial applications, requiring exceptional safety protocols due to its classification as a Category 1B carcinogen and acute toxicity rating. The compound exhibits high volatility and flammability characteristics, with vapors that can form explosive mixtures with air. Its molecular structure features two methyl groups attached to one nitrogen atom of the hydrazine backbone, distinguishing it from other hydrazine derivatives and contributing to its unique reactivity profile. The substance demonstrates severe corrosive properties toward skin and materials, necessitating specialized storage and handling equipment resistant to chemical attack. Unlike less hazardous compounds such as 2,2-dibromo-2-cyanoacetamide used in water treatment, 1,1-dimethylhydrazine requires containment systems designed for both toxicity and flammability concerns. Its high water solubility combined with environmental persistence creates additional challenges for spill management and waste disposal. Primary industrial applications include rocket fuel formulations where it serves as a hypergolic propellant component, pharmaceutical intermediate synthesis for specialized drug manufacturing, and polymer production as a chain extender or cross-linking agent. The aerospace industry particularly values its reliable ignition characteristics and high energy density, though handling requires extensive safety infrastructure. Due to its extreme hazard profile, this material demands comprehensive risk assessment and regulatory compliance verification before procurement. OYSI maintains strict qualification procedures for 1,1-dimethylhydrazine supply, ensuring complete documentation and appropriate safety protocols for authorized industrial customers.

Safety & Classification

Danger
Classification:

Flam. Liq. 2; Carc. 1B; Acute Tox. 3 *; Acute Tox. 3 *; Skin Corr. 1B; Aquatic Chronic 2

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H225

Highly flammable liquid and vapour.

H350

May cause cancer.

H331

Toxic if inhaled.

H301

Toxic if swallowed.

H314

Causes severe skin burns and eye damage.

H411

Toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Toxic

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Harmful

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Toxic

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number1163
ADR Class6.1
Packing GroupI
Tunnel CodeC/D
Proper Shipping NameDimethylhydrazin, asymmetrisch
Marine PollutantNo

Frequently Asked Questions

What is 1,1-dimethylhydrazine?

1,1-dimethylhydrazine is an organic chemical compound with the molecular formula C2H8N2 and CAS number 57-14-7. This hydrazine derivative has a molecular weight of 60.1 g/mol and is classified as a highly hazardous substance due to its carcinogenic, toxic, and corrosive properties. It appears as a colorless to pale yellow liquid with a strong ammonia-like odor and is highly reactive with oxidizing agents.

What are the physicochemical properties of 1,1-dimethylhydrazine?

1,1-dimethylhydrazine is a colorless to pale yellow liquid at room temperature with a characteristic ammonia-like or fishy odor. It is highly water-soluble and miscible with most organic solvents including alcohols and ethers. The compound is hygroscopic, meaning it readily absorbs moisture from air. It has a low flash point making it highly flammable, and it's sensitive to light and air, requiring storage under inert conditions.

What is 1,1-dimethylhydrazine used for?

1,1-dimethylhydrazine is primarily used as a rocket fuel component, specifically as a hypergolic propellant that ignites spontaneously when mixed with oxidizers. It serves as an intermediate in pharmaceutical synthesis and chemical research applications. The compound is also used in specialized industrial processes requiring strong reducing agents. Due to its extreme toxicity and carcinogenic properties, its use is heavily regulated and limited to specialized applications with strict safety protocols.

How to handle 1,1-dimethylhydrazine safely?

1,1-dimethylhydrazine requires extreme safety precautions during handling due to its carcinogenic and highly toxic nature. Personnel must wear full chemical-resistant suits, supplied-air respiratory protection, and chemically resistant gloves. Work must be conducted in well-ventilated areas or fume hoods with emergency eyewash and shower stations nearby. Avoid contact with skin, eyes, and inhalation of vapors. Only trained professionals should handle this substance following strict safety protocols.

How to store 1,1-dimethylhydrazine correctly?

1,1-dimethylhydrazine must be stored in tightly sealed containers made of compatible materials like stainless steel or specially treated glass, kept in cool, dry, well-ventilated areas away from heat, sparks, and oxidizing agents. Storage areas should be secured with restricted access and proper safety signage. The compound should be protected from light and stored under inert gas atmosphere when possible. Secondary containment is essential to prevent environmental contamination.

What to do in case of contact with 1,1-dimethylhydrazine?

Immediate action is critical for any contact with 1,1-dimethylhydrazine. For skin contact, remove contaminated clothing and flush affected area with copious amounts of water for at least 15 minutes. If inhaled, move victim to fresh air immediately and provide oxygen if breathing is difficult. For eye contact, flush with water for at least 15 minutes. Seek immediate medical attention in all cases and inform medical personnel of the chemical identity and exposure circumstances.

How to dispose of 1,1-dimethylhydrazine properly?

1,1-dimethylhydrazine disposal must comply with strict hazardous waste regulations and cannot be disposed of through normal waste streams. The substance requires specialized treatment through licensed hazardous waste disposal facilities equipped to handle carcinogenic and toxic materials. Disposal typically involves high-temperature incineration under controlled conditions. Consult local environmental authorities and waste management specialists to ensure proper disposal methods and documentation are followed according to applicable regulations.

How to transport 1,1-dimethylhydrazine?

1,1-dimethylhydrazine is classified under ADR regulations as Class 6.1 (Toxic substances), Packing Group I, indicating its extremely hazardous nature. Transportation requires specialized packaging, proper labeling with appropriate hazard pictogrammes, and compliance with dangerous goods regulations. Only certified carriers experienced in handling toxic chemicals should transport this substance. Proper documentation, emergency response information, and safety equipment must accompany all shipments according to international transport regulations.

Is 1,1-dimethylhydrazine subject to specific regulations?

1,1-dimethylhydrazine is subject to extensive regulatory oversight due to its carcinogenic classification (Category 1B) under CLP regulation. It falls under REACH registration requirements and various national chemical control laws. The substance requires special authorization for many uses and is subject to workplace exposure limits and environmental discharge restrictions. Companies handling this chemical must maintain detailed safety data sheets, implement risk management measures, and comply with occupational health and safety regulations.

Where to buy 1,1-dimethylhydrazine in Europe?

1,1-dimethylhydrazine is available through specialized chemical distributors like OYSI, which serves the European market with technical-grade chemicals. Due to the substance's extreme hazard classification and regulatory restrictions, purchases typically require proper authorization, demonstrated legitimate use, and compliance with safety and handling requirements. Buyers must provide appropriate credentials and safety infrastructure. Contact OYSI directly to discuss availability, regulatory requirements, and safety specifications for your specific application needs.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.