1-propoxypropane

C6H14O

CAS111-43-3
GHS02 Gefahrensymbol: Entzündbar – Flamme
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
Danger

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Identification

CAS Number
111-43-3
EC Number
203-869-6
UN Number
2384
Index Number
603-045-00-X
PubChem CID
8114

Physical-chemical properties

Molecular Formula
C6H14O
Molar Mass
102.17 g/mol
IUPAC Name
1-propoxypropane

Chemical Identifiers

InChI
InChI=1S/C6H14O/c1-3-5-7-6-4-2/h3-6H2,1-2H3
InChI Key
POLCUAVZOMRGSN-UHFFFAOYSA-N

Overview

1-propoxypropane (CAS 111-43-3) is an organic ether compound characterized by high flammability and moderate volatility properties. This dipropyl ether serves as an important industrial solvent and chemical intermediate in various manufacturing processes. With its molecular formula C6H14O and molar mass of 102.17 g/mol, 1-propoxypropane belongs to the family of aliphatic ethers, sharing structural similarities with other industrial solvents while offering distinct performance characteristics. The compound presents significant safety considerations due to its classification as a Category 2 flammable liquid under GHS regulations, requiring careful handling protocols and appropriate storage conditions. The substance exhibits excellent solvent properties for organic compounds and demonstrates good chemical stability under normal conditions. Its ether linkage provides moderate polarity, making it effective for dissolving both polar and non-polar substances. However, the flammable nature of 1-propoxypropane necessitates strict fire prevention measures, as indicated by the GHS02 flame pictogram and ADR Class 3 transportation classification. Additionally, the compound may cause specific target organ toxicity following single exposure (STOT SE 3), emphasizing the importance of adequate ventilation and personal protective equipment during handling. Primary industrial applications include use as a solvent in paint and coating formulations, as a reaction medium in organic synthesis, and as an extraction solvent in chemical processing. Unlike more aromatic compounds such as ethylbenzene, 1-propoxypropane offers lower toxicity profiles while maintaining effective solvation properties. The compound also finds application in cleaning formulations where its ether characteristics provide enhanced degreasing capabilities. OYSI maintains reliable supply chains for 1-propoxypropane, ensuring consistent availability for European industrial customers requiring this specialized ether solvent.

Safety & Classification

Danger
Classification:

Flam. Liq. 2; STOT SE 3

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H225

Highly flammable liquid and vapour.

H336

May cause drowsiness or dizziness.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Irritant

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2384
ADR Class3
Packing GroupII
Tunnel CodeD/E
Proper Shipping NameDi-n-propylether
Marine PollutantNo

Frequently Asked Questions

What is 1-propoxypropane?

1-propoxypropane is an organic chemical compound with the molecular formula C6H14O and CAS number 111-43-3. It belongs to the ether family and has a molecular weight of 102.17 g/mol. This substance is classified as a flammable liquid category 2 and specific target organ toxicant single exposure category 3, requiring careful handling due to its hazardous properties and danger signal word classification.

What are the physicochemical properties of 1-propoxypropane?

1-propoxypropane is a colorless liquid ether with characteristic ethereal odor at room temperature. As an ether compound, it exhibits limited solubility in water but good solubility in organic solvents. The substance has a relatively low molecular weight of 102.17 g/mol and displays typical ether properties including volatility and flammability, making it suitable for various industrial applications requiring organic solvents.

What is 1-propoxypropane used for?

1-propoxypropane serves primarily as an organic solvent in industrial applications due to its ether properties. It is commonly used in chemical synthesis processes, extraction operations, and as a reaction medium in pharmaceutical and fine chemical manufacturing. The compound also finds application in specialty cleaning formulations and as an intermediate in organic synthesis where its specific solvent properties are required for optimal reaction conditions.

How to handle 1-propoxypropane safely?

1-propoxypropane requires careful handling using appropriate personal protective equipment including safety goggles, chemical-resistant gloves, and protective clothing. Work in well-ventilated areas or under fume hoods to prevent vapor accumulation. Keep away from ignition sources, heat, and open flames due to its Flam. Liq. 2 classification. Avoid skin and eye contact, and prevent inhalation of vapors due to STOT SE 3 classification.

How to store 1-propoxypropane correctly?

1-propoxypropane must be stored in cool, dry, well-ventilated areas away from heat sources, sparks, and open flames due to its flammable liquid category 2 classification. Use appropriate containers made of compatible materials and ensure proper labeling with GHS02 and GHS07 pictograms. Store away from oxidizing agents and incompatible materials. Maintain storage temperatures below recommended limits to prevent vapor buildup and ensure container integrity.

What to do in case of contact with 1-propoxypropane?

1-propoxypropane exposure requires immediate action depending on contact type. For skin contact, remove contaminated clothing and wash thoroughly with soap and water. In case of eye contact, rinse immediately with plenty of water for at least 15 minutes. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek medical attention. Always consult safety data sheets and contact emergency services if serious exposure occurs.

How to dispose of 1-propoxypropane appropriately?

1-propoxypropane disposal must comply with local and European waste regulations as it is classified as hazardous waste due to its flammable and toxic properties. Contact licensed waste disposal companies specialized in handling flammable organic solvents. Never dispose of through regular drainage systems or municipal waste. The substance requires proper classification under waste codes and appropriate treatment methods including incineration at authorized facilities under controlled conditions.

How to transport 1-propoxypropane?

1-propoxypropane is classified under ADR class 3 (flammable liquids) packing group II, requiring compliance with dangerous goods transportation regulations. Use UN-approved packaging and proper hazard labeling during transport. Vehicles must carry appropriate emergency equipment and documentation. Drivers need ADR certification for dangerous goods transport. Ensure proper securing of packages and avoid transport during extreme weather conditions that could affect container integrity.

Is 1-propoxypropane subject to specific regulations?

1-propoxypropane is subject to European REACH and CLP regulations due to its hazardous classification. It requires safety data sheets, proper labeling with danger signal word and GHS pictograms (GHS02, GHS07). The substance is not currently listed as SVHC (Substance of Very High Concern). Users must comply with occupational exposure limits, waste disposal regulations, and transportation requirements under ADR for dangerous goods.

Where to buy 1-propoxypropane in Europe?

1-propoxypropane is available through OYSI, a European distributor specializing in technical chemical products. OYSI provides this substance to industrial customers across Europe with proper documentation, safety data sheets, and regulatory compliance. As a professional chemical distributor, OYSI ensures product quality, appropriate packaging, and adherence to European chemical regulations including REACH and CLP requirements for hazardous substances.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.