1-phenylethanone

1-phenylethanone is an aromatic ketone with the molecular formula C8H8O and CAS number 98-86-2. Also known as acetophenone, it is a colorless to pale yellow liquid with a sweet, almond-like odor. With a molecular weight of 120.15 g/mol, this organic compound features a phenyl group attached to a carbonyl group. It is classified as moderately hazardous with acute toxicity category 4 and eye irritation properties, requiring careful handling in industrial applications.

1-phenylethanone appears as a colorless to pale yellow liquid at room temperature with a characteristic sweet, floral odor reminiscent of almonds or cherries. It has limited solubility in water but dissolves readily in organic solvents like ethanol, ether, and benzene. The compound has a boiling point of approximately 202°C and a melting point around 20°C. Its density is about 1.03 g/cm³, making it slightly denser than water.

1-phenylethanone serves primarily as an intermediate in organic synthesis and pharmaceutical manufacturing. It is widely used in the production of fragrances and flavoring agents due to its pleasant almond-like scent. The compound acts as a precursor for various pharmaceuticals, including hypnotics and antihistamines. Additionally, it finds applications in polymer chemistry, dye manufacturing, and as a photoinitiator in UV-curing systems for coatings and adhesives.

1-phenylethanone requires careful handling due to its acute toxicity (category 4) and eye irritation properties. Always wear appropriate personal protective equipment including safety goggles, chemical-resistant gloves, and protective clothing. Ensure adequate ventilation in work areas to prevent vapor accumulation. Avoid direct skin and eye contact, and do not inhale vapors. Work in well-ventilated areas or under fume hoods, and keep ignition sources away as the compound may be flammable.

1-phenylethanone should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Keep the storage temperature below 25°C to maintain stability and prevent degradation. Store away from strong oxidizing agents, acids, and bases to avoid incompatible reactions. Ensure containers are properly labeled with hazard information and keep in areas accessible only to trained personnel. Use appropriate secondary containment to prevent spills.

In case of skin contact with 1-phenylethanone, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, rinse immediately with clean water for at least 15 minutes and seek medical attention promptly due to its eye irritation properties. If inhaled, move to fresh air immediately. If ingested, do not induce vomiting and seek immediate medical attention. Always consult a physician if symptoms persist.

1-phenylethanone must be disposed of in accordance with local and national hazardous waste regulations. The compound cannot be disposed of in regular waste streams due to its classification as hazardous material. Contact licensed waste disposal companies for proper collection and treatment. Small quantities can often be recovered through distillation for reuse. Never discharge into sewers, waterways, or soil. Maintain proper documentation of waste disposal activities as required by environmental regulations.

1-phenylethanone transport requirements depend on quantity and packaging specifications, as specific ADR classification details are not provided for this substance. Generally, it should be transported in appropriate UN-approved packaging with proper hazard labeling including GHS07 pictogram and "Warning" signal word. Ensure compliance with local dangerous goods regulations and provide safety data sheets to carriers. Use vehicles equipped for chemical transport and ensure drivers have appropriate hazardous materials training and certification.

1-phenylethanone is subject to standard chemical regulations including REACH registration requirements in Europe and CLP classification showing Acute Tox. 4 and Eye Irrit. 2 categories. It is not listed as a Substance of Very High Concern (SVHC) under REACH. The compound requires proper labeling with GHS07 pictogram and "Warning" signal word. Users must comply with occupational health and safety regulations, maintain safety data sheets, and follow proper risk assessment procedures for workplace use.

1-phenylethanone is available through OYSI, a reliable European distributor of technical chemicals serving industrial customers across the continent. OYSI provides quality chemical products with proper documentation, safety data sheets, and regulatory compliance support. As a specialized chemical distributor, OYSI ensures appropriate packaging, labeling, and delivery services for professional users. Contact OYSI directly for availability, specifications, and ordering information to meet your specific industrial or research requirements.