1-phenylethanone

1-phenylethanone is an organic chemical compound with the molecular formula C8H8O and CAS number 98-86-2. Also known as acetophenone, it belongs to the ketone family and has a molecular weight of 120.15 g/mol. This aromatic ketone is characterized by a phenyl group attached to an acetyl group, making it an important intermediate in organic synthesis and industrial applications.

1-phenylethanone appears as a colorless to pale yellow liquid at room temperature with a sweet, floral, almond-like odor. It has a melting point of approximately 20°C and a boiling point of 202°C. The compound is slightly soluble in water but readily soluble in organic solvents such as ethanol, ether, and benzene. Its density is approximately 1.03 g/cm³ at 20°C.

1-phenylethanone serves as a key intermediate in pharmaceutical synthesis, particularly for producing hypnotic and antihistamine drugs. It's widely used in the fragrance industry due to its pleasant almond-like scent, appearing in perfumes and flavoring agents. Additionally, it functions as a solvent in various industrial processes and serves as a starting material for synthesizing other organic compounds in chemical manufacturing.

Safe handling of 1-phenylethanone requires appropriate personal protective equipment including safety goggles, chemical-resistant gloves, and protective clothing. Work in well-ventilated areas or under fume hoods to prevent inhalation. Avoid direct skin and eye contact due to its irritant properties (Eye Irrit. 2, Acute Tox. 4). Keep away from heat sources, sparks, and open flames. Always wash hands thoroughly after handling.

1-phenylethanone should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Keep containers upright and clearly labeled. Store away from strong oxidizing agents and incompatible materials. Maintain storage temperature below 25°C to prevent degradation. Ensure proper secondary containment and keep away from food, beverages, and animal feed areas.

In case of skin contact with 1-phenylethanone, immediately remove contaminated clothing and wash the affected area with plenty of soap and water for at least 15 minutes. For eye contact, rinse immediately with clean water for 15-20 minutes and seek medical attention. If inhaled, move to fresh air immediately. If swallowed, do not induce vomiting and seek immediate medical attention. Always consult a physician when in doubt.

1-phenylethanone waste must be disposed of according to local, national, and international regulations. Do not pour down drains or release into the environment. Contact licensed waste disposal companies for proper treatment and disposal. Small quantities may be suitable for incineration in approved facilities with appropriate emission controls. Always consult local environmental authorities for specific disposal requirements and maintain proper waste documentation.

1-phenylethanone can be transported following general chemical transport guidelines since it doesn't have a specific ADR classification. Use appropriate packaging that prevents leakage and breakage during transport. Ensure containers are properly labeled with chemical identification and hazard information. Follow standard precautions for chemical transport including proper documentation, trained personnel, and emergency response procedures. Consult transport regulations for specific packaging requirements.

1-phenylethanone is regulated under European REACH and CLP regulations, requiring proper classification and labeling as Acute Tox. 4 and Eye Irrit. 2 with Warning signal word and GHS07 pictogram. It is not listed as a Substance of Very High Concern (SVHC). Users must comply with safety data sheet requirements, worker protection measures, and proper hazard communication throughout the supply chain.

1-phenylethanone is available through OYSI, a reliable European distributor of specialty chemicals. OYSI provides high-quality 1-phenylethanone with proper documentation including safety data sheets and certificates of analysis. As an established chemical distributor, OYSI ensures compliance with European regulations and offers technical support for various industrial applications. Contact OYSI directly for availability, specifications, and pricing information for your specific requirements.