1-(dimethoxymethyl)-2-nitrobenzene

1-(dimethoxymethyl)-2-nitrobenzene is an aromatic nitro compound with the molecular formula C9H11NO4 and CAS number 20627-73-0. This chemical features a benzene ring substituted with a nitro group and a dimethoxymethyl group in ortho position. With a molecular weight of 197.19 g/mol, it belongs to the class of substituted nitrobenzenes and is primarily used as an intermediate in organic synthesis.

1-(dimethoxymethyl)-2-nitrobenzene is a solid organic compound at room temperature with characteristic aromatic properties. As a nitrobenzene derivative, it typically exhibits limited water solubility but good solubility in organic solvents. The presence of both electron-withdrawing nitro and electron-donating methoxy groups influences its reactivity and physical properties. Specific parameters like melting point and density should be verified through technical data sheets.

1-(dimethoxymethyl)-2-nitrobenzene serves primarily as an intermediate in organic synthesis and pharmaceutical manufacturing. The compound is valuable in multi-step synthetic processes where the nitro group can be reduced to an amine or the dimethoxymethyl group can be converted to other functional groups. It finds applications in the production of fine chemicals, pharmaceutical intermediates, and specialty compounds requiring specific substitution patterns on the benzene ring.

1-(dimethoxymethyl)-2-nitrobenzene requires careful handling due to its skin sensitization properties (Skin Sens. 1). Wear appropriate personal protective equipment including chemical-resistant gloves, safety glasses, and protective clothing. Work in well-ventilated areas or under fume hoods to avoid inhalation. Avoid direct skin contact and implement proper hygiene measures. The GHS07 pictogram indicates health hazards, requiring adherence to standard laboratory safety protocols for handling sensitizing substances.

1-(dimethoxymethyl)-2-nitrobenzene should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Keep away from incompatible materials such as strong oxidizers and reducing agents. Store separately from food, beverages, and animal feed. Maintain proper inventory management and ensure containers are properly labeled. As a nitro compound, avoid storage near sources of ignition and maintain stable temperature conditions.

In case of skin contact with 1-(dimethoxymethyl)-2-nitrobenzene, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, rinse immediately with clean water for 15 minutes and seek medical attention. If inhaled, move to fresh air immediately. Given its skin sensitization properties, seek medical advice if irritation persists. Always consult the safety data sheet for complete first aid instructions.

1-(dimethoxymethyl)-2-nitrobenzene must be disposed of according to local, national, and international environmental regulations. Do not discharge into sewers, waterways, or soil due to its aquatic chronic toxicity (Aquatic Chronic 2). Contact licensed waste disposal companies specialized in chemical waste management. The waste should be classified and treated as hazardous waste. Incineration in appropriate facilities may be suitable, but always follow regulatory guidelines and obtain proper documentation.

1-(dimethoxymethyl)-2-nitrobenzene is classified as ADR Class 9 (Miscellaneous dangerous substances), Packing Group III for transportation purposes. This classification requires appropriate packaging, labeling, and documentation according to dangerous goods regulations. Use UN-approved packaging and ensure proper hazard labels are affixed. Transportation must comply with ADR/RID regulations for road and rail transport, and similar international regulations for air and sea transport. Proper shipping papers and emergency response information must accompany shipments.

1-(dimethoxymethyl)-2-nitrobenzene is subject to standard chemical regulations including REACH registration requirements in Europe and CLP classification as a skin sensitizer. It is not currently listed as a Substance of Very High Concern (SVHC). Companies must comply with safety data sheet requirements, proper classification and labeling under GHS/CLP, and workplace safety regulations. Users must ensure proper risk assessments and implement appropriate risk management measures according to regulatory requirements.

1-(dimethoxymethyl)-2-nitrobenzene is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides quality chemical products with proper documentation, safety data sheets, and regulatory compliance for industrial and research applications. As experienced chemical distributors, OYSI ensures reliable supply chains and technical support for customers across Europe. Contact OYSI directly for availability, specifications, packaging options, and delivery to your location within Europe.