2-phenylsulfanylaniline
C12H11NS
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Identification
- CAS Number
- 1134-94-7
- EC Number
- 413-030-8
- UN Number
- 3077
- Index Number
- 612-181-00-9
- PubChem CID
- 365393
Physical-chemical properties
- Molecular Formula
- C12H11NS
- Molar Mass
- 201.29 g/mol
- IUPAC Name
- 2-phenylsulfanylaniline
Chemical Identifiers
- InChI
- InChI=1S/C12H11NS/c13-11-8-4-5-9-12(11)14-10-6-2-1-3-7-10/h1-9H,13H2
- InChI Key
- DGBISJKLNVVJGD-UHFFFAOYSA-N
Overview
2-phenylsulfanylaniline (CAS 1134-94-7) is an aromatic amine compound with sulfur-bridged phenyl groups used in specialized chemical synthesis applications. This organic compound, also known by its IUPAC name 2-phenylsulfanylaniline, represents a distinctive class of aromatic amines characterized by the presence of both aniline and thioether functional groups. With a molecular formula of C12H11NS and molecular weight of 201.29 g/mol, this substance exhibits unique chemical properties derived from its dual aromatic ring system connected through a sulfur bridge. The compound's structure combines the reactivity of primary aromatic amines with the electron-donating effects of the phenylsulfanyl substituent, making it valuable for various synthetic applications. From a safety perspective, 2-phenylsulfanylaniline is classified as a skin sensitizer (Skin Sens. 1) and presents chronic aquatic toxicity concerns (Aquatic Chronic 2), requiring appropriate handling protocols and environmental considerations. The substance carries GHS07 and GHS09 pictograms with a "Warning" signal word, indicating moderate hazard levels that necessitate proper personal protective equipment and controlled storage conditions. Transportation falls under ADR Class 9 miscellaneous dangerous goods. Industrial applications primarily include use as an intermediate in pharmaceutical synthesis, specialty dye manufacturing, and advanced materials research. The compound's unique electronic properties make it particularly useful in developing compounds with specific photochemical or electrochemical characteristics. In synthetic chemistry, it shares certain applications with related aromatic compounds, though its specific structure offers distinct advantages over simpler aniline derivatives or compounds like 2,4-dihydroxy-N-(2-methoxyphenyl)benzamide in targeted synthetic routes. OYSI maintains reliable supply chains for 2-phenylsulfanylaniline to support European industrial and research applications with consistent quality standards.
Safety & Classification
Skin Sens. 1; Aquatic Chronic 2
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Skin Contact
Measures if substance contacts the skin
First Aid Actions
- +P302IF ON SKIN:
- +P352Wash with plenty of water.
- +P361Take off immediately all contaminated clothing.
- +P313Get medical advice/attention.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 3077 |
| ADR Class | 9 |
| Packing Group | III |
| Tunnel Code | - |
| Proper Shipping Name | 2-Phenylthioanilin |
| Marine Pollutant | No |
Frequently Asked Questions
What is 2-phenylsulfanylaniline?
2-phenylsulfanylaniline is an organic chemical compound with the molecular formula C12H11NS and CAS number 1134-94-7. This aromatic amine derivative contains both aniline and phenyl sulfide functional groups, giving it a molecular weight of 201.29 g/mol. It is classified as a skin sensitizer and poses chronic aquatic toxicity risks, requiring careful handling in industrial applications.
What are the physicochemical properties of 2-phenylsulfanylaniline?
2-phenylsulfanylaniline is a solid organic compound at room temperature with the molecular formula C12H11NS. As an aromatic amine containing sulfur, it typically appears as a crystalline material. The compound has a molecular weight of 201.29 g/mol and contains both nitrogen and sulfur heteroatoms within its aromatic structure, influencing its chemical reactivity and solubility characteristics.
What is 2-phenylsulfanylaniline used for?
2-phenylsulfanylaniline serves as an important intermediate in organic synthesis and pharmaceutical chemistry. The compound is primarily used in the manufacture of dyes, pigments, and specialized chemical intermediates. Its unique structure, combining aniline and phenyl sulfide functionalities, makes it valuable for developing complex organic molecules in research and industrial applications, particularly in fine chemical synthesis.
How to handle 2-phenylsulfanylaniline safely?
2-phenylsulfanylaniline requires careful handling due to its skin sensitization properties (Skin Sens. 1 classification). Operators must wear appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Ensure adequate ventilation in work areas and avoid direct skin contact. Handle the material in well-ventilated areas or under fume hoods to minimize inhalation exposure risks.
How to store 2-phenylsulfanylaniline correctly?
2-phenylsulfanylaniline should be stored in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Keep containers tightly closed and properly labeled according to GHS requirements (GHS07, GHS09 pictograms). Store away from incompatible materials such as strong oxidizers and acids. Ensure storage areas have appropriate spill containment measures to prevent environmental contamination.
What to do in case of contact with 2-phenylsulfanylaniline?
Immediate action is required in case of skin contact with 2-phenylsulfanylaniline due to its sensitization properties. Remove contaminated clothing and wash affected skin thoroughly with soap and water for at least 15 minutes. In case of eye contact, flush immediately with clean water for 15 minutes. If inhaled, move to fresh air. Seek medical attention if irritation persists or sensitization symptoms develop.
How to dispose of 2-phenylsulfanylaniline properly?
2-phenylsulfanylaniline disposal must comply with local and national waste regulations due to its hazardous properties. The material cannot be disposed of in regular waste streams and requires treatment as hazardous chemical waste. Contact licensed waste disposal contractors for proper handling and treatment. Prevent release to the environment due to its Aquatic Chronic 2 classification, which poses risks to aquatic ecosystems.
How to transport 2-phenylsulfanylaniline?
2-phenylsulfanylaniline is classified under ADR Class 9 (Miscellaneous dangerous substances), Packing Group III for transportation. This classification requires appropriate packaging, labeling, and documentation according to dangerous goods regulations. Shipments must display proper hazard labels and be accompanied by transport documents. Ensure packaging meets UN specification requirements and prevents leakage during transport.
Is 2-phenylsulfanylaniline subject to specific regulations?
2-phenylsulfanylaniline is subject to various European chemical regulations including REACH registration requirements and CLP classification obligations. The compound is not currently listed as a Substance of Very High Concern (SVHC). However, its classification as Skin Sens. 1 and Aquatic Chronic 2 means it must be properly labeled, handled, and reported according to CLP regulation requirements throughout the supply chain.
Where to buy 2-phenylsulfanylaniline in Europe?
2-phenylsulfanylaniline is available through OYSI, a leading European distributor of specialty chemicals and intermediates. OYSI provides reliable supply of this compound to industrial customers across Europe, ensuring proper packaging, documentation, and regulatory compliance. As a professional chemical distributor, OYSI maintains appropriate storage and handling facilities to guarantee product quality and safe delivery to customers.
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Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.