1-chloro-2-(2-chloroethoxy)ethane
C4H8Cl2O
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Identification
- CAS Number
- 111-44-4
- EC Number
- 203-870-1
- UN Number
- 2810
- Index Number
- 603-029-00-2
- PubChem CID
- 8115
Physical-chemical properties
- Molecular Formula
- C4H8Cl2O
- Molar Mass
- 143.01 g/mol
- IUPAC Name
- 1-chloro-2-(2-chloroethoxy)ethane
Chemical Identifiers
- InChI
- InChI=1S/C4H8Cl2O/c5-1-3-7-4-2-6/h1-4H2
- InChI Key
- ZNSMNVMLTJELDZ-UHFFFAOYSA-N
Overview
1-chloro-2-(2-chloroethoxy)ethane (CAS 111-44-4) is a dichlorinated ether compound with significant toxicological properties and industrial solvent applications. This organochlorine compound, also known by its IUPAC designation 1-chloro-2-(2-chloroethoxy)ethane, represents an important chemical intermediate in various industrial processes. With a molecular formula of C4H8Cl2O and molecular weight of 143.01 g/mol, this substance belongs to the family of chlorinated ethers that have found widespread use in chemical manufacturing and synthesis applications. The compound exhibits severe hazard characteristics, classified under multiple danger categories including carcinogenicity (Category 2) and acute toxicity (Categories 1 and 2). These classifications necessitate stringent handling protocols and specialized safety equipment during industrial use. The substance carries the "Danger" signal word and is associated with GHS08 (health hazard) and GHS06 (skull and crossbones) pictograms, reflecting its potential for serious health effects including suspected carcinogenic properties and acute toxicity risks. From a regulatory perspective, 1-chloro-2-(2-chloroethoxy)ethane falls under ADR Class 6.1 for transportation purposes, indicating its classification as a toxic substance. Like other chlorinated compounds such as chloromethylbenzene, it requires careful consideration of environmental and occupational exposure limits during handling and storage. Primary industrial applications include its use as a chemical intermediate in organic synthesis, particularly in the production of pharmaceuticals and agrochemicals. The compound also serves as a specialized solvent in certain manufacturing processes where its unique chemical properties are advantageous. Additionally, it functions as a reagent in various chemical transformations requiring chlorinated ether functionality. OYSI maintains reliable supply chains for 1-chloro-2-(2-chloroethoxy)ethane, ensuring consistent availability for qualified industrial customers across European markets.
Safety & Classification
Carc. 2; Acute Tox. 2 *; Acute Tox. 1; Acute Tox. 2 *
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Inhalation
Measures if vapours or dust are inhaled
First Aid Actions
- +P304IF INHALED:
- +P340Remove person to fresh air and keep comfortable for breathing.
- +P311Call a POISON CENTER/doctor.
Related hazard statements:
Skin Contact
Measures if substance contacts the skin
First Aid Actions
- +P302IF ON SKIN:
- +P352Wash with plenty of water.
- +P361Take off immediately all contaminated clothing.
- +P313Get medical advice/attention.
Related hazard statements:
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 2810 |
| ADR Class | 6.1 |
| Packing Group | II |
| Tunnel Code | D/E |
| Proper Shipping Name | 2,2'-Dichlordiethylether, Flp. > 60 °C |
| Marine Pollutant | No |
Frequently Asked Questions
What is 1-chloro-2-(2-chloroethoxy)ethane?
1-chloro-2-(2-chloroethoxy)ethane is an organochlorine chemical compound with the molecular formula C4H8Cl2O and CAS number 111-44-4. This substance has a molecular weight of 143.01 g/mol and contains two chlorine atoms connected by an ether linkage. It is classified as a highly hazardous chemical with significant toxicity and carcinogenic properties, requiring strict safety protocols for handling and use in industrial applications.
What are the physicochemical properties of 1-chloro-2-(2-chloroethoxy)ethane?
1-chloro-2-(2-chloroethoxy)ethane is a chlorinated ether compound that typically appears as a colorless to pale yellow liquid at room temperature. Due to its chlorinated structure and ether functionality, it exhibits moderate volatility and lipophilic characteristics. The compound has limited water solubility but shows good solubility in organic solvents. Its physicochemical properties make it useful as an industrial solvent and chemical intermediate.
What is 1-chloro-2-(2-chloroethoxy)ethane used for?
1-chloro-2-(2-chloroethoxy)ethane serves primarily as a chemical intermediate in organic synthesis and industrial processes. It is utilized in the production of various pharmaceutical compounds, specialty chemicals, and as a solvent in specific industrial applications. Due to its high toxicity classification (Acute Tox. 1 and 2), its use is restricted to professional industrial settings with appropriate safety controls and regulatory compliance.
How to handle 1-chloro-2-(2-chloroethoxy)ethane safely?
1-chloro-2-(2-chloroethoxy)ethane requires maximum safety precautions due to its Acute Tox. 1 and carcinogenic classification. Essential PPE includes chemical-resistant gloves, protective clothing, safety goggles, and respiratory protection. Work must be conducted in well-ventilated areas or under fume hoods. Avoid skin contact, inhalation, and ingestion completely. Only trained personnel should handle this substance following strict industrial hygiene protocols and emergency procedures.
How to store 1-chloro-2-(2-chloroethoxy)ethane correctly?
1-chloro-2-(2-chloroethoxy)ethane must be stored in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Use original containers or approved chemical-resistant containers with proper labeling including GHS pictograms GHS08 and GHS06. Storage areas should be restricted to authorized personnel only, equipped with appropriate containment measures, and comply with local regulations for highly toxic substances.
What to do in case of contact with 1-chloro-2-(2-chloroethoxy)ethane?
Immediate action is critical due to the substance's high toxicity. For skin contact, remove contaminated clothing and rinse extensively with water for at least 15 minutes. In case of eye contact, flush immediately with clean water for 15 minutes. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting. Seek immediate medical attention in all cases and provide the safety data sheet to medical personnel.
How to dispose of 1-chloro-2-(2-chloroethoxy)ethane appropriately?
1-chloro-2-(2-chloroethoxy)ethane requires disposal as hazardous waste through licensed waste management companies specializing in toxic chemical disposal. The substance cannot be disposed of in regular waste streams due to its high toxicity and carcinogenic properties. Disposal must comply with national and EU waste regulations, including proper documentation, labeling, and transport by certified hazardous waste carriers to authorized treatment facilities.
How to transport 1-chloro-2-(2-chloroethoxy)ethane?
1-chloro-2-(2-chloroethoxy)ethane is classified under ADR Class 6.1 (toxic substances) Packing Group II, indicating high toxicity requiring special transport precautions. Transportation must comply with dangerous goods regulations, using approved packaging, proper labeling with toxic substance markings, and transport documentation. Only certified carriers with hazardous materials authorization can transport this substance, following specific routing and emergency response requirements.
Is 1-chloro-2-(2-chloroethoxy)ethane subject to specific regulations?
1-chloro-2-(2-chloroethoxy)ethane is subject to comprehensive EU chemical regulations including REACH registration and CLP classification requirements. Its Carc. 2 and high acute toxicity classifications trigger specific handling, labeling, and reporting obligations. Companies must ensure proper risk assessments, exposure controls, and regulatory compliance. Professional users require adequate training and implementation of risk management measures according to extended safety data sheets.
Where to buy 1-chloro-2-(2-chloroethoxy)ethane in Europe?
1-chloro-2-(2-chloroethoxy)ethane is available through OYSI, a specialized European distributor of technical chemicals. As a highly regulated substance due to its toxicity classification, purchase is restricted to qualified industrial customers with appropriate licenses and safety infrastructure. OYSI provides comprehensive regulatory support, safety documentation, and ensures compliance with EU chemical regulations for professional applications requiring this specialized chemical intermediate.
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Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.