1-chloro-2-(2-chloroethoxy)ethane
C4H8Cl2O
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Identification
- CAS Number
- 111-44-4
- EC Number
- 203-870-1
- UN Number
- 2810
- Index Number
- 603-029-00-2
- PubChem CID
- 8115
Physical-chemical properties
- Molecular Formula
- C4H8Cl2O
- Molar Mass
- 143.01 g/mol
- IUPAC Name
- 1-chloro-2-(2-chloroethoxy)ethane
Chemical Identifiers
- InChI
- InChI=1S/C4H8Cl2O/c5-1-3-7-4-2-6/h1-4H2
- InChI Key
- ZNSMNVMLTJELDZ-UHFFFAOYSA-N
Overview
1-chloro-2-(2-chloroethoxy)ethane (CAS 111-44-4) is a dichlorinated ether compound with significant toxicity and carcinogenic potential. This chlorinated organic compound, also known by its IUPAC name 1-chloro-2-(2-chloroethoxy)ethane, represents a class of halogenated ethers with substantial industrial relevance despite serious health and safety concerns. With a molecular formula of C4H8Cl2O and molecular weight of 143.01 g/mol, this colorless liquid exhibits the characteristic properties of chlorinated solvents while presenting unique challenges due to its ether linkage structure. The compound carries severe hazard classifications under the GHS system, including Category 2 carcinogenicity and multiple acute toxicity categories, requiring extreme caution in handling and storage. Its classification under ADR Class 6.1 as a toxic substance reflects the serious risks associated with exposure through inhalation, skin contact, or ingestion. The presence of two chlorine atoms and an ether oxygen creates a molecule with both lipophilic and moderately polar characteristics, influencing its behavior in biological systems and environmental fate. Industrial applications typically involve its use as a chemical intermediate in organic synthesis, particularly in the production of specialized polymers and as a solvent in specific manufacturing processes where its unique chemical properties are advantageous. Like other halogenated compounds such as chloromethylbenzene, it finds application in pharmaceutical intermediate synthesis, though always under strictly controlled conditions due to safety requirements. The compound's reactivity profile makes it valuable in certain alkylation reactions and as a building block for more complex molecular structures. However, its classification as a suspected carcinogen necessitates comprehensive risk management protocols in any commercial application. OYSI provides 1-chloro-2-(2-chloroethoxy)ethane to qualified industrial customers with full regulatory documentation and safety data sheets for compliant handling.
Safety & Classification
Carc. 2; Acute Tox. 2 *; Acute Tox. 1; Acute Tox. 2 *
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Inhalation
Measures if vapours or dust are inhaled
First Aid Actions
- +P304IF INHALED:
- +P340Remove person to fresh air and keep comfortable for breathing.
- +P311Call a POISON CENTER/doctor.
Related hazard statements:
Skin Contact
Measures if substance contacts the skin
First Aid Actions
- +P302IF ON SKIN:
- +P352Wash with plenty of water.
- +P361Take off immediately all contaminated clothing.
- +P313Get medical advice/attention.
Related hazard statements:
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 2810 |
| ADR Class | 6.1 |
| Packing Group | II |
| Tunnel Code | D/E |
| Proper Shipping Name | 2,2'-Dichlordiethylether, Flp. > 60 °C |
| Marine Pollutant | No |
Frequently Asked Questions
What is 1-chloro-2-(2-chloroethoxy)ethane?
1-chloro-2-(2-chloroethoxy)ethane is an organochlorine compound with the molecular formula C4H8Cl2O and CAS number 111-44-4. This chemical substance has a molecular weight of 143.01 g/mol and contains two chlorine atoms connected by an ether linkage. It is classified as a highly hazardous substance with significant toxicity and potential carcinogenic properties, requiring careful handling and strict safety protocols in industrial applications.
What are the physicochemical properties of 1-chloro-2-(2-chloroethoxy)ethane?
1-chloro-2-(2-chloroethoxy)ethane is a colorless liquid at room temperature with a characteristic ether-like odor. As an organochlorine compound, it exhibits moderate polarity due to the presence of both chlorine atoms and the ether oxygen. The substance is partially soluble in water and highly soluble in organic solvents such as alcohols, ethers, and hydrocarbons, making it suitable for various industrial solvent applications.
What is 1-chloro-2-(2-chloroethoxy)ethane used for?
1-chloro-2-(2-chloroethoxy)ethane is primarily used as an industrial solvent and chemical intermediate in organic synthesis. It serves as a reagent in pharmaceutical manufacturing, pesticide production, and specialty chemical synthesis. Due to its excellent solvating properties for various organic compounds, it is also employed in extraction processes and as a reaction medium in chemical manufacturing, though its use is restricted due to safety concerns.
How to handle 1-chloro-2-(2-chloroethoxy)ethane safely?
1-chloro-2-(2-chloroethoxy)ethane must be handled with extreme caution due to its high toxicity and carcinogenic potential. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and respiratory protection. Work should be conducted in well-ventilated areas or under fume hoods. Avoid skin contact, inhalation, and ingestion. Emergency shower and eyewash stations must be readily accessible, and personnel should be trained in proper handling procedures.
How to store 1-chloro-2-(2-chloroethoxy)ethane correctly?
1-chloro-2-(2-chloroethoxy)ethane should be stored in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Use only approved containers made of compatible materials, ensuring tight sealing to prevent vapor escape. Store separately from incompatible materials such as strong bases, oxidizing agents, and reactive metals. Implement proper inventory management and ensure storage areas are equipped with appropriate fire suppression systems and spill containment measures.
What to do in case of contact with 1-chloro-2-(2-chloroethoxy)ethane?
Immediate medical attention is required for any exposure to 1-chloro-2-(2-chloroethoxy)ethane. For skin contact, remove contaminated clothing and rinse thoroughly with water for at least 15 minutes. If inhaled, move to fresh air immediately and seek medical help. For eye contact, flush with clean water for 15 minutes while holding eyelids open. If ingested, do not induce vomiting and contact poison control immediately.
How to dispose of 1-chloro-2-(2-chloroethoxy)ethane appropriately?
1-chloro-2-(2-chloroethoxy)ethane must be disposed of as hazardous waste through licensed waste management companies specializing in toxic chemical disposal. The substance requires specific treatment methods such as high-temperature incineration in approved facilities. Never discharge into sewers, waterways, or soil. Waste containers must be properly labeled and stored according to hazardous waste regulations. Consult local environmental authorities for specific disposal requirements and approved disposal facilities.
How to transport 1-chloro-2-(2-chloroethoxy)ethane?
1-chloro-2-(2-chloroethoxy)ethane is classified under ADR Class 6.1 (Toxic substances), Packing Group II, indicating high toxicity during transport. Shipments must comply with dangerous goods regulations, using UN-approved packaging and proper hazard labeling. Vehicles must carry appropriate emergency equipment and documentation. Drivers require dangerous goods training certification. Transport should be planned to avoid populated areas when possible, and emergency response procedures must be readily available.
Is 1-chloro-2-(2-chloroethoxy)ethane subject to specific regulations?
1-chloro-2-(2-chloroethoxy)ethane is subject to strict regulatory oversight under REACH and CLP regulations in Europe due to its high toxicity and carcinogenic classification. The substance requires safety data sheets, hazard communication, and may have restrictions on certain uses. Companies must comply with occupational exposure limits, implement risk management measures, and maintain detailed records. Registration requirements and authorization procedures may apply depending on quantities and intended uses.
Where to buy 1-chloro-2-(2-chloroethoxy)ethane in Europe?
1-chloro-2-(2-chloroethoxy)ethane is available through specialized chemical distributors in Europe, including OYSI, which supplies high-quality industrial chemicals to European markets. Due to the substance's hazardous nature, purchases typically require appropriate licenses, safety documentation, and end-use verification. OYSI provides comprehensive support including regulatory compliance assistance, proper packaging, and safe delivery services to qualified industrial customers throughout Europe.
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Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.