Trichlorophosphane

Cl3P

trichlorophosphane

CAS7719-12-2
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS05 Gefahrensymbol: Ätzend – Ätzwirkung
Danger

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Identification

CAS Number
7719-12-2
EC Number
231-749-3
UN Number
1809
Index Number
015-007-00-4
PubChem CID
24387

Physical-chemical properties

Molecular Formula
Cl3P
Molar Mass
137.33 g/mol
IUPAC Name
trichlorophosphane

Chemical Identifiers

InChI
InChI=1S/Cl3P/c1-4(2)3
InChI Key
FAIAAWCVCHQXDN-UHFFFAOYSA-N

Overview

Trichlorophosphane (CAS 7719-12-2) is an inorganic phosphorus compound with highly reactive and corrosive properties used primarily as a chemical intermediate. This colorless to pale yellow liquid represents one of the most important phosphorus halides in industrial chemistry, serving as a crucial building block for numerous phosphorus-containing compounds. Trichlorophosphane exhibits exceptional reactivity due to the electronegativity difference between phosphorus and chlorine atoms, making it an invaluable reagent for synthetic applications requiring phosphorus incorporation. The compound presents significant safety considerations, classified under multiple acute toxicity categories and skin corrosion class 1A, necessitating stringent handling protocols. Its corrosive nature demands specialized storage conditions and personal protective equipment to prevent exposure through inhalation, skin contact, or ingestion. The ADR classification 6.1 reflects its toxic properties during transportation, requiring compliance with hazardous materials regulations. Industrial applications center on its role as an intermediate in organophosphorus chemistry, particularly in the synthesis of phosphine derivatives and flame retardants. The pharmaceutical industry utilizes trichlorophosphane for producing phosphorus-containing active ingredients, while the agrochemical sector employs it in pesticide manufacturing. Unlike simpler halogenated compounds such as chloromethylbenzene, trichlorophosphane's phosphorus center provides unique reactivity patterns essential for creating phosphorus-carbon and phosphorus-nitrogen bonds. The compound's hygroscopic nature requires anhydrous conditions during handling and storage, as moisture contact leads to rapid hydrolysis and hydrogen chloride formation. This characteristic distinguishes it from more stable halogenated intermediates and emphasizes the need for specialized equipment and expertise. OYSI provides trichlorophosphane to qualified industrial customers with comprehensive technical support and regulatory documentation for European markets.

Safety & Classification

Danger
Classification:

Acute Tox. 2 *; Acute Tox. 2 *; STOT RE 2 *; Skin Corr. 1A

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H330

Fatal if inhaled.

H300

Fatal if swallowed.

H373

May cause damage to organs through prolonged or repeated exposure.

H314

Causes severe skin burns and eye damage.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Fatal

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Harmful

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Fatal

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number1809
ADR Class6.1
Packing GroupI
Tunnel CodeC/D
Proper Shipping NamePhosphortrichlorid
Marine PollutantNo

Frequently Asked Questions

What is trichlorophosphane?

Trichlorophosphane is an inorganic chemical compound with the molecular formula Cl3P and CAS number 7719-12-2. This phosphorus halide has a molecular weight of 137.33 g/mol and serves as an important intermediate in phosphorus chemistry. It is classified as a highly hazardous substance with acute toxicity and corrosive properties, requiring specialized handling procedures in industrial applications.

What are the physicochemical properties of trichlorophosphane?

Trichlorophosphane is a colorless to pale yellow liquid at room temperature with a pungent, irritating odor. It has a boiling point of 76°C and is highly reactive with water, producing hydrochloric acid and phosphorous acid. The compound is soluble in organic solvents but reacts violently with moisture, making it moisture-sensitive and requiring anhydrous storage conditions.

What is trichlorophosphane used for?

Trichlorophosphane is primarily used as an intermediate in the synthesis of organophosphorus compounds, including pesticides, flame retardants, and plasticizers. It serves as a key reagent in pharmaceutical manufacturing and in the production of phosphine derivatives. The compound is also utilized in semiconductor processing and as a precursor for various phosphorus-containing specialty chemicals in industrial applications.

How to handle trichlorophosphane safely?

Trichlorophosphane requires strict safety measures including full-face respirators, chemical-resistant gloves, and complete body protection due to its corrosive and toxic nature. Work must be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Personnel should be trained in emergency procedures and have immediate access to safety showers and eyewash stations when handling this dangerous substance.

How to store trichlorophosphane correctly?

Trichlorophosphane must be stored in tightly sealed containers in cool, dry, well-ventilated areas away from moisture and incompatible materials. Storage areas should be equipped with appropriate containment systems and maintained below 25°C. The substance should be kept separate from water, alcohols, and oxidizing agents to prevent dangerous reactions and maintain product stability.

What to do in case of contact with trichlorophosphane?

Immediate first aid for trichlorophosphane contact includes removing contaminated clothing and flushing affected skin or eyes with copious amounts of water for at least 15 minutes. If inhaled, move the person to fresh air immediately and seek medical attention. Never induce vomiting if swallowed, and contact emergency medical services promptly as this substance can cause severe chemical burns and systemic toxicity.

How to dispose of trichlorophosphane appropriately?

Trichlorophosphane disposal must comply with local and national hazardous waste regulations as it is classified as dangerous waste. The substance should be neutralized carefully by specialized waste treatment facilities equipped to handle corrosive and toxic materials. Never pour into drains or regular waste streams, and always use licensed hazardous waste contractors for collection and treatment.

How to transport trichlorophosphane?

Trichlorophosphane is classified under ADR as Class 6.1 (Toxic substances) with Packing Group I, indicating high danger level during transport. It requires specialized packaging meeting UN specifications and must be transported by trained personnel with appropriate documentation. Vehicles must display proper hazard placards and follow designated routing restrictions for dangerous goods transportation.

Is trichlorophosphane subject to specific regulations?

Trichlorophosphane is subject to strict regulations under REACH and CLP in Europe due to its high toxicity and corrosive properties. It requires safety data sheets, proper classification labeling with GHS pictograms (GHS05, GHS06, GHS08), and the danger signal word. The substance may have restrictions on use and requires appropriate risk management measures for professional handling.

Where to buy trichlorophosphane in Europe?

Trichlorophosphane is available through OYSI, a specialized European distributor of technical chemicals with expertise in handling dangerous substances. As a professional chemical supplier, OYSI provides proper documentation, regulatory compliance support, and technical assistance for industrial customers requiring this specialized phosphorus compound. Contact OYSI directly for availability, specifications, and regulatory guidance for your specific application needs.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.