Cyclopentyl carbonochloridate
C6H9ClO2
cyclopentyl carbonochloridate
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Identification
- CAS Number
- 50715-28-1
- EC Number
- 411-460-0
- UN Number
- 2742
- Index Number
- 607-332-00-0
- PubChem CID
- 2735892
Physical-chemical properties
- Molecular Formula
- C6H9ClO2
- Molar Mass
- 148.59 g/mol
- IUPAC Name
- cyclopentyl carbonochloridate
Chemical Identifiers
- InChI
- InChI=1S/C6H9ClO2/c7-6(8)9-5-3-1-2-4-5/h5H,1-4H2
- InChI Key
- ZFQCRLNKHHXELH-UHFFFAOYSA-N
Overview
Cyclopentyl carbonochloridate (CAS 50715-28-1) is a reactive organochlorine compound with carbonyl chloride functionality used in chemical synthesis applications. This specialized chemical intermediate belongs to the chloroformate family, characterized by its highly reactive acyl chloride group attached to a cyclopentyl ring structure. With the molecular formula C6H9ClO2 and a molecular weight of 148.59 g/mol, cyclopentyl carbonochloridate exhibits significant reactivity due to its electrophilic carbonyl carbon, making it valuable for various organic transformations and industrial processes. The compound presents notable safety considerations that require careful handling protocols. Classified under multiple hazard categories including flammable liquid (Category 3), acute toxicity, and eye damage (Category 1), it demands specialized storage and handling procedures. The presence of GHS pictograms including flame, skull and crossbones, health hazard, and corrosion symbols underscores its potentially dangerous nature. Transportation falls under ADR Class 6.1, reflecting its toxic properties during shipping and distribution. Like other reactive chloroformates such as 2-(chloromethyl)oxirane, this compound readily undergoes nucleophilic substitution reactions, making it particularly useful in pharmaceutical intermediate synthesis and specialty chemical manufacturing. Primary industrial applications include its use as an acylating agent in organic synthesis, as a building block for pharmaceutical compounds, and in the production of specialized polymers and protective group chemistry where the cyclopentyl moiety provides specific steric and electronic properties. OYSI maintains reliable supply chains for cyclopentyl carbonochloridate to support European chemical manufacturers and research institutions requiring this specialized intermediate.
Safety & Classification
Flam. Liq. 3; Acute Tox. 3 *; Acute Tox. 4 *; STOT RE 2 *; Eye Dam. 1; Skin Sens. 1
GHS Pictograms
Flame
GHS02
Flammable. May ignite on contact with air, water, or heat sources.
Skull and Crossbones
GHS06
Acute toxicity. Fatal if swallowed, in contact with skin, or if inhaled.
Health Hazard
GHS08
Serious health hazard. May cause cancer, organ damage, or genetic defects.
Corrosion
GHS05
Corrosive. Causes severe skin burns and eye damage.
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Inhalation
Measures if vapours or dust are inhaled
First Aid Actions
- +P304IF INHALED:
- +P340Remove person to fresh air and keep comfortable for breathing.
- +P311Call a POISON CENTER/doctor.
Related hazard statements:
Skin Contact
Measures if substance contacts the skin
First Aid Actions
- +P302IF ON SKIN:
- +P352Wash with plenty of water.
- +P361Take off immediately all contaminated clothing.
- +P313Get medical advice/attention.
Related hazard statements:
Eye Contact
Measures if substance gets into the eyes
First Aid Actions
- +P305IF IN EYES:
- +P351Rinse cautiously with water for several minutes.
- +P338Remove contact lenses, if present and easy to do. Continue rinsing.
- +P313Get medical advice/attention.
Related hazard statements:
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 2742 |
| ADR Class | 6.1 |
| Packing Group | II |
| Tunnel Code | D/E |
| Proper Shipping Name | Cyclopentylchlorformiat |
| Marine Pollutant | No |
Frequently Asked Questions
What is cyclopentyl carbonochloridate?
Cyclopentyl carbonochloridate is an organic chemical compound with the molecular formula C6H9ClO2 and CAS number 50715-28-1. This chloroformate derivative has a molecular weight of 148.59 g/mol and belongs to the family of carbonyl chlorides. It is classified as a hazardous substance with multiple danger categories including flammability, acute toxicity, and corrosive properties, requiring careful handling in industrial applications.
What are the physicochemical properties of cyclopentyl carbonochloridate?
Cyclopentyl carbonochloridate is a liquid organic compound at room temperature with the molecular formula C6H9ClO2. As a chloroformate ester, it typically exhibits high reactivity with water and alcohols, forming hydrochloric acid upon hydrolysis. The compound is flammable (category 3) and likely has a pungent odor characteristic of chloroformates. Its exact physical properties such as boiling point and density require consultation of detailed technical datasheets.
What is cyclopentyl carbonochloridate used for?
Cyclopentyl carbonochloridate serves as an important intermediate in organic synthesis and pharmaceutical manufacturing. It is primarily used as a reagent for introducing cyclopentyl carbamate protecting groups in peptide synthesis and for preparing cyclopentyl esters of carboxylic acids. The compound finds applications in fine chemical synthesis, pharmaceutical research, and as a building block for more complex organic molecules in specialized chemical processes.
How to handle cyclopentyl carbonochloridate safely?
Cyclopentyl carbonochloridate requires strict safety protocols due to its acute toxicity and corrosive nature. Essential PPE includes chemical-resistant gloves, safety goggles or face shield, and protective clothing. Work must be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid contact with skin, eyes, and clothing. Keep away from heat sources and ignition due to its flammable properties (category 3).
How to store cyclopentyl carbonochloridate correctly?
Cyclopentyl carbonochloridate must be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and ignition. Keep containers away from moisture as the compound reacts with water to form corrosive hydrochloric acid. Store separately from bases, alcohols, and amines to prevent dangerous reactions. Ensure storage areas have appropriate spill containment and are accessible only to trained personnel with proper safety equipment.
What to do in case of contact with cyclopentyl carbonochloridate?
Immediate action is critical due to the compound's corrosive and toxic properties. For skin contact, immediately remove contaminated clothing and rinse affected area with plenty of water for at least 15 minutes. For eye contact, flush immediately with water for at least 15 minutes and seek medical attention. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical attention. Always consult safety data sheets for complete emergency procedures.
How to dispose of cyclopentyl carbonochloridate properly?
Cyclopentyl carbonochloridate disposal must comply with local and national hazardous waste regulations as it is classified as toxic and corrosive waste. The compound cannot be disposed of in regular waste streams or sewers. Contact licensed hazardous waste disposal companies for proper treatment and disposal. Small quantities may require neutralization under controlled conditions by trained personnel. Always consult local environmental authorities for specific disposal requirements and approved facilities.
How to transport cyclopentyl carbonochloridate?
Cyclopentyl carbonochloridate is classified under ADR as Class 6.1 (Toxic substances), Packing Group II, indicating significant transport restrictions. Transportation requires appropriate UN-specification packaging, proper labeling with GHS pictograms (GHS02, GHS06, GHS08, GHS05), and accompanying transport documents. Only certified carriers experienced in hazardous materials transport should handle shipments. Vehicles must carry appropriate emergency equipment and drivers must have hazardous materials training certification.
Is cyclopentyl carbonochloridate subject to specific regulations?
Cyclopentyl carbonochloridate is subject to multiple regulatory frameworks including REACH registration requirements for European markets and CLP classification as a dangerous substance. It is not currently listed as an SVHC (Substance of Very High Concern) but falls under strict handling, storage, and transport regulations due to its hazard classification. Users must comply with occupational safety regulations, environmental protection laws, and chemical safety assessments before use.
Where to buy cyclopentyl carbonochloridate in Europe?
Cyclopentyl carbonochloridate is available through OYSI, a specialized European distributor of technical chemicals serving industrial and research customers across Europe. As a professional chemical supplier, OYSI ensures proper handling, documentation, and compliance with all regulatory requirements for hazardous substances. Contact OYSI directly for availability, technical specifications, safety documentation, and pricing information. Purchases require appropriate business credentials and intended use declarations due to the compound's hazardous classification.
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Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.