Cyclopentyl carbonochloridate

C6H9ClO2

cyclopentyl carbonochloridate

CAS50715-28-1
GHS02 Gefahrensymbol: Entzündbar – Flamme
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS05 Gefahrensymbol: Ätzend – Ätzwirkung
Danger

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Identification

CAS Number
50715-28-1
EC Number
411-460-0
UN Number
2742
Index Number
607-332-00-0
PubChem CID
2735892

Physical-chemical properties

Molecular Formula
C6H9ClO2
Molar Mass
148.59 g/mol
IUPAC Name
cyclopentyl carbonochloridate

Chemical Identifiers

InChI
InChI=1S/C6H9ClO2/c7-6(8)9-5-3-1-2-4-5/h5H,1-4H2
InChI Key
ZFQCRLNKHHXELH-UHFFFAOYSA-N

Overview

Cyclopentyl carbonochloridate (CAS 50715-28-1) is a reactive organochlorine compound with carbonyl chloride functionality used in chemical synthesis applications. This specialized chemical intermediate belongs to the chloroformate family, characterized by its highly reactive acyl chloride group attached to a cyclopentyl ring structure. With the molecular formula C6H9ClO2 and a molecular weight of 148.59 g/mol, cyclopentyl carbonochloridate exhibits significant reactivity due to its electrophilic carbonyl carbon, making it valuable for various organic transformations and industrial processes. The compound presents notable safety considerations that require careful handling protocols. Classified under multiple hazard categories including flammable liquid (Category 3), acute toxicity, and eye damage (Category 1), it demands specialized storage and handling procedures. The presence of GHS pictograms including flame, skull and crossbones, health hazard, and corrosion symbols underscores its potentially dangerous nature. Transportation falls under ADR Class 6.1, reflecting its toxic properties during shipping and distribution. Like other reactive chloroformates such as 2-(chloromethyl)oxirane, this compound readily undergoes nucleophilic substitution reactions, making it particularly useful in pharmaceutical intermediate synthesis and specialty chemical manufacturing. Primary industrial applications include its use as an acylating agent in organic synthesis, as a building block for pharmaceutical compounds, and in the production of specialized polymers and protective group chemistry where the cyclopentyl moiety provides specific steric and electronic properties. OYSI maintains reliable supply chains for cyclopentyl carbonochloridate to support European chemical manufacturers and research institutions requiring this specialized intermediate.

Safety & Classification

Danger
Classification:

Flam. Liq. 3; Acute Tox. 3 *; Acute Tox. 4 *; STOT RE 2 *; Eye Dam. 1; Skin Sens. 1

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H226

Flammable liquid and vapour.

H331

Toxic if inhaled.

H302

Harmful if swallowed.

H373

May cause damage to organs through prolonged or repeated exposure.

H318

Causes serious eye damage.

H317

May cause an allergic skin reaction.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Toxic

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Irritant

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Harmful

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2742
ADR Class6.1
Packing GroupII
Tunnel CodeD/E
Proper Shipping NameCyclopentylchlorformiat
Marine PollutantNo

Frequently Asked Questions

What is cyclopentyl carbonochloridate?

Cyclopentyl carbonochloridate is an organic chemical compound with the molecular formula C6H9ClO2 and CAS number 50715-28-1. This chloroformate derivative has a molecular weight of 148.59 g/mol and belongs to the family of carbonyl chlorides. It is classified as a hazardous substance with multiple danger categories including flammability, acute toxicity, and corrosive properties, requiring careful handling in industrial applications.

What are the physicochemical properties of cyclopentyl carbonochloridate?

Cyclopentyl carbonochloridate is a liquid organic compound at room temperature with the molecular formula C6H9ClO2. As a chloroformate ester, it typically exhibits high reactivity with water and alcohols, forming hydrochloric acid upon hydrolysis. The compound is flammable (category 3) and likely has a pungent odor characteristic of chloroformates. Its exact physical properties such as boiling point and density require consultation of detailed technical datasheets.

What is cyclopentyl carbonochloridate used for?

Cyclopentyl carbonochloridate serves as an important intermediate in organic synthesis and pharmaceutical manufacturing. It is primarily used as a reagent for introducing cyclopentyl carbamate protecting groups in peptide synthesis and for preparing cyclopentyl esters of carboxylic acids. The compound finds applications in fine chemical synthesis, pharmaceutical research, and as a building block for more complex organic molecules in specialized chemical processes.

How to handle cyclopentyl carbonochloridate safely?

Cyclopentyl carbonochloridate requires strict safety protocols due to its acute toxicity and corrosive nature. Essential PPE includes chemical-resistant gloves, safety goggles or face shield, and protective clothing. Work must be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid contact with skin, eyes, and clothing. Keep away from heat sources and ignition due to its flammable properties (category 3).

How to store cyclopentyl carbonochloridate correctly?

Cyclopentyl carbonochloridate must be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and ignition. Keep containers away from moisture as the compound reacts with water to form corrosive hydrochloric acid. Store separately from bases, alcohols, and amines to prevent dangerous reactions. Ensure storage areas have appropriate spill containment and are accessible only to trained personnel with proper safety equipment.

What to do in case of contact with cyclopentyl carbonochloridate?

Immediate action is critical due to the compound's corrosive and toxic properties. For skin contact, immediately remove contaminated clothing and rinse affected area with plenty of water for at least 15 minutes. For eye contact, flush immediately with water for at least 15 minutes and seek medical attention. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical attention. Always consult safety data sheets for complete emergency procedures.

How to dispose of cyclopentyl carbonochloridate properly?

Cyclopentyl carbonochloridate disposal must comply with local and national hazardous waste regulations as it is classified as toxic and corrosive waste. The compound cannot be disposed of in regular waste streams or sewers. Contact licensed hazardous waste disposal companies for proper treatment and disposal. Small quantities may require neutralization under controlled conditions by trained personnel. Always consult local environmental authorities for specific disposal requirements and approved facilities.

How to transport cyclopentyl carbonochloridate?

Cyclopentyl carbonochloridate is classified under ADR as Class 6.1 (Toxic substances), Packing Group II, indicating significant transport restrictions. Transportation requires appropriate UN-specification packaging, proper labeling with GHS pictograms (GHS02, GHS06, GHS08, GHS05), and accompanying transport documents. Only certified carriers experienced in hazardous materials transport should handle shipments. Vehicles must carry appropriate emergency equipment and drivers must have hazardous materials training certification.

Is cyclopentyl carbonochloridate subject to specific regulations?

Cyclopentyl carbonochloridate is subject to multiple regulatory frameworks including REACH registration requirements for European markets and CLP classification as a dangerous substance. It is not currently listed as an SVHC (Substance of Very High Concern) but falls under strict handling, storage, and transport regulations due to its hazard classification. Users must comply with occupational safety regulations, environmental protection laws, and chemical safety assessments before use.

Where to buy cyclopentyl carbonochloridate in Europe?

Cyclopentyl carbonochloridate is available through OYSI, a specialized European distributor of technical chemicals serving industrial and research customers across Europe. As a professional chemical supplier, OYSI ensures proper handling, documentation, and compliance with all regulatory requirements for hazardous substances. Contact OYSI directly for availability, technical specifications, safety documentation, and pricing information. Purchases require appropriate business credentials and intended use declarations due to the compound's hazardous classification.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.