Trichloromethylbenzene
C7H5Cl3
trichloromethylbenzene
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Identification
- CAS Number
- 98-07-7
- EC Number
- 202-634-5
- UN Number
- 2226
- Index Number
- 602-038-00-9
- PubChem CID
- 7367
Physical-chemical properties
- Molecular Formula
- C7H5Cl3
- Molar Mass
- 195.50 g/mol
- IUPAC Name
- trichloromethylbenzene
Chemical Identifiers
- InChI
- InChI=1S/C7H5Cl3/c8-7(9,10)6-4-2-1-3-5-6/h1-5H
- InChI Key
- XEMRAKSQROQPBR-UHFFFAOYSA-N
Overview
Trichloromethylbenzene (CAS 98-07-7) is an organochlorine compound with significant industrial applications and notable hazard classifications requiring careful handling protocols. This aromatic halogenated compound, also known by its IUPAC designation trichloromethylbenzene, represents an important intermediate in chemical synthesis processes. With a molecular formula of C7H5Cl3 and molecular weight of 195.5 g/mol, this substance exhibits the characteristic properties of chlorinated aromatic compounds. The molecule consists of a benzene ring substituted with a trichloromethyl group, creating a versatile building block for various chemical transformations. The safety profile of trichloromethylbenzene demands particular attention due to its classification as a Category 1B carcinogen, along with acute toxicity ratings and potential for causing serious eye damage and skin irritation. The compound carries the "Danger" signal word and is associated with GHS pictograms GHS08, GHS06, and GHS05, reflecting its health hazards, acute toxicity, and corrosive properties. Its ADR Class 8 designation indicates corrosive material handling requirements during transportation. Industrial applications of trichloromethylbenzene primarily focus on its role as a chemical intermediate in the synthesis of pharmaceuticals, agrochemicals, and specialty chemicals. The compound serves as a key building block in manufacturing processes where selective chlorination and aromatic substitution reactions are required. Its reactivity profile makes it particularly valuable in producing complex organic molecules where precise functional group placement is essential. While structurally distinct from compounds like pentachloro-lambda5-phosphane, trichloromethylbenzene shares similar industrial handling requirements due to its halogenated nature and associated safety considerations. OYSI maintains reliable supply chains for trichloromethylbenzene to support diverse industrial applications across European markets.
Safety & Classification
Carc. 1B; Acute Tox. 3 *; Acute Tox. 4 *; STOT SE 3; Skin Irrit. 2; Eye Dam. 1
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Inhalation
Measures if vapours or dust are inhaled
Skin Contact
Measures if substance contacts the skin
First Aid Actions
- +P302IF ON SKIN:
- +P352Wash with plenty of water.
- +P361Take off immediately all contaminated clothing.
- +P313Get medical advice/attention.
Related hazard statements:
Eye Contact
Measures if substance gets into the eyes
First Aid Actions
- +P305IF IN EYES:
- +P351Rinse cautiously with water for several minutes.
- +P338Remove contact lenses, if present and easy to do. Continue rinsing.
- +P313Get medical advice/attention.
Related hazard statements:
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 2226 |
| ADR Class | 8 |
| Packing Group | II |
| Tunnel Code | E |
| Proper Shipping Name | Benzotrichlorid |
| Marine Pollutant | No |
Frequently Asked Questions
What is trichloromethylbenzene?
Trichloromethylbenzene is an organochlorine compound with the molecular formula C7H5Cl3 and CAS number 98-07-7. This chemical consists of a benzene ring with a trichloromethyl group attached, resulting in a molecular weight of 195.5 g/mol. It is classified as a highly hazardous substance with significant health risks including carcinogenicity, acute toxicity, and potential for causing serious eye damage and skin irritation.
What are the physicochemical properties of trichloromethylbenzene?
Trichloromethylbenzene is typically a colorless to pale yellow liquid at room temperature with a characteristic aromatic odor. The compound has a density higher than water due to its chlorine content and is generally insoluble in water but soluble in organic solvents such as alcohols, ethers, and hydrocarbons. Its high chlorine content makes it chemically stable but potentially reactive under certain conditions.
What is trichloromethylbenzene used for?
Trichloromethylbenzene is primarily used as an intermediate in organic synthesis and pharmaceutical manufacturing. It serves as a building block for producing various chemical compounds, particularly in the synthesis of pesticides, dyes, and specialty chemicals. Due to its carcinogenic properties and toxicity, its industrial applications are strictly regulated and limited to controlled professional environments with appropriate safety measures.
How to handle trichloromethylbenzene safely?
Trichloromethylbenzene requires extreme caution during handling due to its carcinogenic and toxic properties. Essential personal protective equipment includes chemical-resistant gloves, safety goggles or face shields, and respiratory protection. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation. Avoid skin and eye contact at all costs, and ensure emergency eyewash stations and safety showers are readily accessible.
How to store trichloromethylbenzene correctly?
Trichloromethylbenzene must be stored in tightly sealed, chemically compatible containers in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Storage areas should be equipped with appropriate containment systems and separated from incompatible materials such as strong bases, oxidizing agents, and metals. Access should be restricted to authorized personnel only, with proper labeling and safety documentation maintained at all times.
What to do in case of contact with trichloromethylbenzene?
Immediate action is critical following trichloromethylbenzene contact. For skin contact, remove contaminated clothing and wash affected areas with soap and water for at least 15 minutes. In case of eye contact, flush immediately with clean water for 15-20 minutes while holding eyelids open. If inhaled, move to fresh air immediately. Seek medical attention promptly in all cases of exposure, bringing the safety data sheet for reference.
How to dispose of trichloromethylbenzene properly?
Trichloromethylbenzene disposal must comply with local and international hazardous waste regulations due to its carcinogenic classification. The substance cannot be disposed of in regular waste streams and requires treatment at licensed hazardous waste facilities. Incineration at high temperatures with appropriate emission controls or chemical treatment methods are typically required. Always consult local environmental authorities and waste management specialists for specific disposal requirements.
How to transport trichloromethylbenzene?
Trichloromethylbenzene is classified under ADR Class 8 (corrosive substances) with Packing Group II, indicating moderate danger during transport. Packages must meet UN specification requirements with proper marking, labeling, and documentation. Transport vehicles require appropriate placarding and drivers must carry emergency response information. Only authorized carriers experienced in hazardous materials transport should handle shipments of this substance.
Is trichloromethylbenzene subject to specific regulations?
Trichloromethylbenzene is subject to extensive regulatory oversight under REACH, CLP, and other international chemical safety frameworks due to its carcinogenic classification (Category 1B). Registration requirements apply for manufacturers and importers, with strict exposure limits and risk management measures mandated. Special authorization may be required for certain uses, and comprehensive safety data sheets must accompany all commercial quantities.
Where to buy trichloromethylbenzene in Europe?
Trichloromethylbenzene is available through OYSI, a specialized European distributor of technical chemicals with expertise in hazardous substances. As a regulated carcinogenic compound, purchase requires proper documentation, end-use declarations, and compliance verification. OYSI provides comprehensive technical support, safety documentation, and regulatory guidance to ensure compliant procurement and use of this restricted chemical substance across European markets.
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Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.