2-bromo-2-nitropropan-1-ol

C3H6BrNO3

CAS24403-04-1
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS05 Gefahrensymbol: Ätzend – Ätzwirkung
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Danger

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Identification

CAS Number
24403-04-1
EC Number
407-030-7
UN Number
2923
Index Number
609-062-00-9
PubChem CID
205966

Physical-chemical properties

Molecular Formula
C3H6BrNO3
Molar Mass
183.99 g/mol
IUPAC Name
2-bromo-2-nitropropan-1-ol

Chemical Identifiers

InChI
InChI=1S/C3H6BrNO3/c1-3(4,2-6)5(7)8/h6H,2H2,1H3
InChI Key
NYWJACXVDUOPFY-UHFFFAOYSA-N

Overview

2-bromo-2-nitropropan-1-ol (CAS 24403-04-1) is a halogenated nitroalcohol compound with antimicrobial and preservative properties used in industrial applications. This specialized chemical compound, with the molecular formula C3H6BrNO3 and molecular weight of 183.99 g/mol, represents an important class of organobromine compounds containing both nitro and hydroxyl functional groups. The unique combination of bromine, nitro, and alcohol functionalities in its structure provides distinctive chemical reactivity and biological activity profiles that make it valuable for specific industrial applications. The compound exhibits significant safety considerations, classified under multiple hazard categories including acute toxicity (categories 3 and 4), skin corrosion (1B), skin sensitization, and specific target organ toxicity with repeated exposure (category 2). Its classification as ADR class 8 indicates corrosive properties requiring careful handling protocols. The presence of GHS pictograms including skull and crossbones (GHS06), health hazard (GHS08), corrosion (GHS05), and environmental hazard (GHS09) emphasizes the need for appropriate safety measures during storage, handling, and transportation. Primary industrial applications include antimicrobial preservation systems, particularly in formulations where both biocidal activity and chemical stability are required. The compound finds use in specialized coating formulations and as an intermediate in organic synthesis processes. Unlike simpler compounds such as pentanedial, 2-bromo-2-nitropropan-1-ol offers enhanced stability and controlled release properties in preservative applications. Professional users requiring this compound for industrial applications can source 2-bromo-2-nitropropan-1-ol through OYSI's European distribution network, ensuring reliable supply chain management and technical support for specialized chemical requirements.

Safety & Classification

Danger
Classification:

Acute Tox. 3 *; Acute Tox. 4 *; STOT RE 2 *; Skin Corr. 1B; Skin Sens. 1; Aquatic Acute 1; Aquati...

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H311

Toxic in contact with skin.

H302

Harmful if swallowed.

H373

May cause damage to organs through prolonged or repeated exposure.

H314

Causes severe skin burns and eye damage.

H317

May cause an allergic skin reaction.

H400

Very toxic to aquatic life.

H410

Very toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Skin Contact

Toxic

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Harmful

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2923
ADR Class8
Packing GroupII
Tunnel CodeE
Proper Shipping Name2-Brom-2-nitropropanol, fest
Marine PollutantNo

Frequently Asked Questions

What is 2-bromo-2-nitropropan-1-ol?

2-bromo-2-nitropropan-1-ol is an organohalogen compound with the molecular formula C3H6BrNO3 and CAS number 24403-04-1. This chemical substance contains both bromine and nitro functional groups attached to a propanol backbone, giving it a molecular weight of 183.99 g/mol. It is classified as a hazardous substance with multiple danger classifications including acute toxicity, skin corrosion, and environmental hazards, requiring careful handling in industrial applications.

What are the physicochemical properties of 2-bromo-2-nitropropan-1-ol?

2-bromo-2-nitropropan-1-ol is an organic compound with a molecular mass of 183.99 g/mol and the formula C3H6BrNO3. The presence of both bromine and nitro groups significantly influences its chemical behavior and stability. Due to its molecular structure containing hydroxyl, bromo, and nitro functional groups, it exhibits polar characteristics. Specific physical properties such as melting point, boiling point, and solubility data should be consulted from technical datasheets for precise handling requirements.

What is 2-bromo-2-nitropropan-1-ol used for?

2-bromo-2-nitropropan-1-ol is primarily used as an intermediate in organic synthesis and chemical manufacturing processes. Its unique combination of functional groups makes it valuable for pharmaceutical synthesis, specialty chemical production, and research applications. The compound serves as a building block for more complex molecules in medicinal chemistry and fine chemical manufacturing. Due to its hazardous nature, its use is restricted to professional industrial settings with appropriate safety controls and expertise.

How to handle 2-bromo-2-nitropropan-1-ol safely?

2-bromo-2-nitropropan-1-ol requires strict safety protocols due to its Skin Corr. 1B and Acute Tox. 3-4 classifications. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, face protection, and appropriate respiratory protection. Work must be conducted in well-ventilated areas or under fume hoods. Avoid skin and eye contact completely, and prevent inhalation of vapors. Emergency shower and eyewash stations should be readily accessible when handling this corrosive and toxic substance.

How to store 2-bromo-2-nitropropan-1-ol correctly?

2-bromo-2-nitropropan-1-ol must be stored in a cool, dry, well-ventilated area away from incompatible materials and ignition sources. Use corrosion-resistant containers with tight-fitting lids due to its corrosive properties. Storage areas should be equipped with appropriate containment systems and maintained at stable temperatures. Keep away from oxidizing agents, strong bases, and reactive metals. Access should be restricted to trained personnel only, and storage areas must comply with local chemical storage regulations.

What to do in case of contact with 2-bromo-2-nitropropan-1-ol?

Immediate action is critical due to the substance's Skin Corr. 1B classification. For skin contact, immediately remove contaminated clothing and flush affected area with copious amounts of water for at least 15 minutes. In case of eye contact, rinse thoroughly with water and seek immediate medical attention. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek emergency medical care. Always consult the safety data sheet and contact poison control or emergency services when exposure occurs.

How to dispose of 2-bromo-2-nitropropan-1-ol appropriately?

2-bromo-2-nitropropan-1-ol must be disposed of as hazardous waste through licensed waste management companies specializing in chemical disposal. The substance cannot be disposed of in regular waste streams due to its toxic and corrosive properties. Disposal must comply with local, national, and EU waste regulations including the Waste Framework Directive. Containers should be properly labeled, and disposal documentation must be maintained. Neutralization or treatment may be required before final disposal depending on local regulations.

How to transport 2-bromo-2-nitropropan-1-ol?

2-bromo-2-nitropropan-1-ol is classified as ADR Class 8 (corrosive substances), Packing Group II, indicating medium danger level for transport. Transportation requires appropriate UN-approved packaging, proper labeling with GHS pictogrammes (GHS05, GHS06, GHS08, GHS09), and transport documentation. Vehicles must carry appropriate emergency equipment and placards. Only trained drivers with ADR certification can transport this substance. Shipping must comply with international dangerous goods regulations including ADR for road transport within Europe.

Is 2-bromo-2-nitropropan-1-ol subject to specific regulations?

2-bromo-2-nitropropan-1-ol is subject to multiple European regulations including REACH registration, CLP classification and labeling requirements. It is not currently listed as an SVHC (Substance of Very High Concern), but its hazard classifications require compliance with occupational health and safety directives. Users must maintain safety data sheets, implement risk assessments, and follow workplace exposure limits. Import/export may require additional permits, and industrial users must report usage under REACH obligations depending on quantities handled.

Where to buy 2-bromo-2-nitropropan-1-ol in Europe?

2-bromo-2-nitropropan-1-ol is available through OYSI, a specialized European distributor of technical chemicals. As a professional chemical supplier, OYSI can provide this regulated substance to qualified industrial customers with appropriate handling capabilities and regulatory compliance. Due to its hazardous nature and transport restrictions (ADR Class 8), procurement requires proper documentation, safety assessments, and adherence to chemical handling regulations. Contact OYSI directly for availability, technical specifications, and regulatory compliance support for your specific application requirements.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.