Tribromophosphane

Br3P

tribromophosphane

CAS7789-60-8
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS05 Gefahrensymbol: Ätzend – Ätzwirkung
Danger

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Identification

CAS Number
7789-60-8
EC Number
232-178-2
UN Number
1808
Index Number
015-103-00-6
PubChem CID
24614

Physical-chemical properties

Molecular Formula
Br3P
Molar Mass
270.69 g/mol
IUPAC Name
tribromophosphane

Chemical Identifiers

InChI
InChI=1S/Br3P/c1-4(2)3
InChI Key
IPNPIHIZVLFAFP-UHFFFAOYSA-N

Overview

Tribromophosphane (CAS 7789-60-8) is a phosphorus trihalide compound characterized by its highly corrosive properties and potential respiratory toxicity. This inorganic brominated phosphorus compound serves as an important intermediate in various chemical synthesis processes and specialized industrial applications. As a member of the phosphorus trihalide family, tribromophosphane exhibits typical reactivity patterns associated with these compounds. The molecule consists of a central phosphorus atom bonded to three bromine atoms, resulting in a pyramidal molecular geometry. This structure contributes to its significant chemical reactivity, particularly with water and other nucleophilic substances, making it a valuable reagent in organic and inorganic synthesis. The compound presents serious safety considerations due to its classification as STOT SE 3 and Skin Corr. 1B under the GHS system. The associated danger pictograms GHS05 and GHS07 indicate both corrosive and health hazard properties. Its ADR classification as Class 8 (corrosive substances) reflects the material's potential to cause severe skin burns and eye damage upon contact. Proper handling requires specialized equipment and trained personnel due to these inherent risks. Industrial applications of tribromophosphane include its use as a brominating agent in pharmaceutical synthesis, as an intermediate in the production of flame retardants, and in specialized chemical manufacturing processes. Unlike simpler compounds such as hydrogen chloride, tribromophosphane offers selective bromination capabilities that are particularly valuable in complex synthetic pathways. The compound's reactivity profile makes it useful in applications where controlled bromination is required, distinguishing it from other halogenating agents in terms of selectivity and reaction conditions. OYSI maintains reliable supply chains for tribromophosphane to support European industrial customers requiring this specialized chemical intermediate.

Safety & Classification

Danger
Classification:

STOT SE 3; Skin Corr. 1B

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H335

May cause respiratory irritation.

H314

Causes severe skin burns and eye damage.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Irritant

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Harmful

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number1808
ADR Class8
Packing GroupII
Tunnel CodeE
Proper Shipping NamePhosphortribromid
Marine PollutantNo

Frequently Asked Questions

What is tribromophosphane?

Tribromophosphane is an inorganic phosphorus compound with the molecular formula Br3P and CAS number 7789-60-8. This chemical substance has a molecular weight of 270.69 g/mol and belongs to the family of phosphorus trihalides. It is classified as a corrosive substance that can cause serious skin burns and eye damage, as well as specific target organ toxicity. Tribromophosphane is primarily used in specialized chemical synthesis and industrial applications requiring phosphorus-bromine chemistry.

What are the physicochemical properties of tribromophosphane?

Tribromophosphane is typically a colorless to pale yellow liquid at room temperature with a pungent, irritating odor. It has a molecular weight of 270.69 g/mol and is highly reactive with moisture, decomposing in the presence of water to form phosphorous acid and hydrogen bromide. The compound is soluble in organic solvents but reacts violently with water. It has a high density and low vapor pressure, making proper ventilation essential during handling.

What is tribromophosphane used for?

Tribromophosphane is primarily used as a brominating agent in organic synthesis and as an intermediate in the production of organophosphorus compounds. It serves as a reagent for introducing bromine atoms into organic molecules and for synthesizing phosphorus-containing pharmaceuticals, agrochemicals, and specialty chemicals. The compound is also utilized in research laboratories for specific chemical transformations and in the manufacture of flame retardants and other bromine-containing industrial products.

How to handle tribromophosphane safely?

Tribromophosphane must be handled with extreme caution due to its corrosive properties. Always wear appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Work in a well-ventilated area or under a fume hood to avoid inhalation of vapors. Avoid contact with skin, eyes, and clothing. Keep away from moisture and water sources as the compound reacts violently. Use only non-sparking tools and ensure proper grounding to prevent static electricity buildup.

How to store tribromophosphane correctly?

Tribromophosphane should be stored in tightly sealed, corrosion-resistant containers in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Keep containers away from moisture, water, alcohols, and other reactive substances. Store separately from oxidizing agents, acids, and bases. The storage area should be equipped with appropriate spill containment measures and emergency equipment. Regularly inspect containers for signs of corrosion or leakage and maintain inventory records for regulatory compliance.

What to do in case of contact with tribromophosphane?

In case of skin contact with tribromophosphane, immediately remove contaminated clothing and flush the affected area with copious amounts of water for at least 15 minutes. For eye contact, rinse immediately with water for at least 15 minutes and seek medical attention. If inhaled, move the person to fresh air and seek medical help if breathing difficulties occur. In case of ingestion, do not induce vomiting and seek immediate medical attention. Always consult a physician and provide the safety data sheet.

How to dispose of tribromophosphane properly?

Tribromophosphane must be disposed of as hazardous waste in accordance with local, national, and international regulations. Contact licensed hazardous waste disposal companies for proper collection and treatment. Never dispose of the substance down drains, sewers, or into the environment. Small quantities can be neutralized carefully by trained personnel using appropriate procedures, but this should only be done following established protocols. Maintain proper documentation of all disposal activities for regulatory compliance and traceability.

How to transport tribromophosphane?

Tribromophosphane is classified as a Class 8 corrosive substance under ADR regulations with Packing Group II. It must be transported in appropriate UN-specification packaging designed for corrosive liquids. Vehicles must display proper hazard placards and carry emergency response information. Drivers require ADR training certificates, and transport documents must include proper shipping names and hazard classifications. Ensure packages are properly labeled, secured, and protected from damage during transit while following all applicable transport regulations.

Is tribromophosphane subject to specific regulations?

Tribromophosphane is subject to various European regulations including REACH registration requirements and CLP classification as Skin Corr. 1B and STOT SE 3. It is not currently listed as a Substance of Very High Concern (SVHC). Users must comply with occupational safety regulations, proper labeling requirements with GHS pictograms GHS05 and GHS07, and the 'Danger' signal word. Additional national regulations may apply regarding use restrictions, reporting requirements, and workplace exposure limits that must be followed.

Where to buy tribromophosphane in Europe?

Tribromophosphane is available through OYSI, a specialized European distributor of technical chemicals. As an established chemical supplier, OYSI can provide this regulated substance to qualified industrial and research customers with proper documentation and compliance requirements. Contact OYSI directly for availability, technical specifications, and regulatory support. Due to the hazardous nature of this substance, purchases typically require verification of intended use, proper handling capabilities, and compliance with applicable regulations for professional users only.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.