Tetramethylplumbane
C4H12Pb
tetramethylplumbane
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Identification
- CAS Number
- 75-74-1
- EC Number
- 200-897-0
- UN Number
- 3483
- Index Number
- 082-002-00-1
- PubChem CID
- 6394
Physical-chemical properties
- Molecular Formula
- C4H12Pb
- Molar Mass
- 267.00 g/mol
- IUPAC Name
- tetramethylplumbane
Chemical Identifiers
- InChI
- InChI=1S/4CH3.Pb/h4*1H3;
- InChI Key
- XOOGZRUBTYCLHG-UHFFFAOYSA-N
Overview
Tetramethylplumbane (CAS 75-74-1) is an organolead compound with highly toxic properties and significant environmental impact concerns. This organometallic compound, also known by its IUPAC name tetramethylplumbane, represents one of the most hazardous lead-based chemicals in industrial applications. With its molecular formula C4H12Pb and molecular weight of 267 g/mol, tetramethylplumbane belongs to the family of tetraalkyllead compounds that have historically played important roles in various industrial processes. The substance carries severe health warnings, classified as Reproductive Toxicity Category 1A, Acute Toxicity Categories 1 and 2, and poses significant risks for specific target organ toxicity with repeated exposure. The compound's safety profile demands extreme caution, as indicated by its GHS pictograms including GHS08 (health hazard), GHS06 (skull and crossbones), and GHS09 (environmental hazard). Its classification under ADR Class 6.1 reflects its status as a toxic substance requiring specialized handling and transportation protocols. Unlike some related organometallic compounds such as N-methylaniline or phenylhydrazine, tetramethylplumbane presents particularly severe lead-specific toxicity concerns that affect multiple organ systems. Primary industrial applications include use as a specialized reagent in organometallic synthesis, as an intermediate in certain chemical manufacturing processes, and in specific research applications requiring organolead compounds. However, its use has become increasingly restricted due to environmental and health regulations across European markets. The compound's aquatic toxicity classification emphasizes the need for stringent containment and waste management procedures. OYSI maintains strict protocols for the handling and distribution of this specialized chemical, ensuring compliance with all European safety and environmental regulations.
Safety & Classification
Repr. 1A; Acute Tox. 2 *; Acute Tox. 1; Acute Tox. 2 *; STOT RE 2 *; Aquatic Acute 1; Aquatic Chr...
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Inhalation
Measures if vapours or dust are inhaled
First Aid Actions
- +P304IF INHALED:
- +P340Remove person to fresh air and keep comfortable for breathing.
- +P311Call a POISON CENTER/doctor.
Related hazard statements:
Skin Contact
Measures if substance contacts the skin
First Aid Actions
- +P302IF ON SKIN:
- +P352Wash with plenty of water.
- +P361Take off immediately all contaminated clothing.
- +P313Get medical advice/attention.
Related hazard statements:
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 3483 |
| ADR Class | 6.1 |
| Packing Group | I |
| Tunnel Code | C/D |
| Proper Shipping Name | Tetramethylblei |
| Marine Pollutant | No |
Frequently Asked Questions
What is tetramethylplumbane?
Tetramethylplumbane is an organolead compound with the chemical formula C4H12Pb and CAS number 75-74-1. This chemical substance has a molecular weight of 267 g/mol and belongs to the family of alkyl lead compounds. It is classified as extremely hazardous due to its high toxicity and reproductive toxicity properties, requiring strict safety measures for handling and use.
What are the physicochemical properties of tetramethylplumbane?
Tetramethylplumbane is an organometallic compound that typically appears as a colorless liquid at room temperature. As an alkyl lead derivative, it exhibits high volatility and can readily evaporate. The compound is relatively unstable when exposed to air and light, potentially decomposing over time. Its physical properties make it particularly hazardous due to potential inhalation exposure through vapor formation.
What is tetramethylplumbane used for?
Tetramethylplumbane is primarily used in specialized research applications and as a precursor in organometallic synthesis. Historically, organolead compounds were used in gasoline as anti-knock agents, but such applications have been largely discontinued due to environmental and health concerns. Today, its use is extremely limited and restricted to specific industrial processes under strict regulatory control.
How to handle tetramethylplumbane safely?
Tetramethylplumbane requires extreme safety precautions due to its acute toxicity classification (Acute Tox. 1 and 2). Essential protective equipment includes chemical-resistant gloves, full face protection, and appropriate respiratory protection. Work must be conducted in well-ventilated areas or under fume hoods. Avoid skin contact, inhalation, and ingestion completely. Emergency procedures should be readily available, and only trained personnel should handle this substance.
How to store tetramethylplumbane correctly?
Tetramethylplumbane must be stored in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Use appropriate secondary containment and ensure containers are tightly sealed to prevent vapor release. Storage areas should be restricted to authorized personnel only and equipped with appropriate emergency equipment. Keep away from incompatible materials and ensure proper labeling with GHS pictograms GHS06, GHS08, and GHS09.
What to do in case of contact with tetramethylplumbane?
Tetramethylplumbane exposure requires immediate emergency response due to its extreme toxicity. In case of skin contact, remove contaminated clothing and rinse thoroughly with water for at least 15 minutes. For eye contact, flush immediately with water and seek medical attention. If inhaled, move to fresh air immediately and seek urgent medical care. Any exposure should be treated as a medical emergency requiring professional intervention.
How to dispose of tetramethylplumbane appropriately?
Tetramethylplumbane disposal must comply with strict hazardous waste regulations due to its high toxicity and environmental impact. The substance cannot be disposed of through normal waste streams and requires specialized hazardous waste treatment facilities. Contact licensed waste management companies experienced in handling toxic organometallic compounds. Ensure proper documentation and follow all local, national, and European waste disposal regulations.
How to transport tetramethylplumbane?
Tetramethylplumbane is classified under ADR Class 6.1 (toxic substances) with Packing Group I, indicating maximum danger level. Transportation requires specialized packaging meeting UN specifications and proper hazardous goods documentation. Only certified carriers experienced in handling highly toxic materials should transport this substance. Shipments must include appropriate emergency response information and comply with all dangerous goods transport regulations.
Is tetramethylplumbane subject to specific regulations?
Tetramethylplumbane is subject to extensive regulatory control under European chemical legislation including REACH and CLP regulations. Its classification as Repr. 1A and multiple acute toxicity categories triggers strict handling requirements. The substance may face restrictions or authorization requirements for certain uses. Companies must ensure full compliance with notification, classification, and safety data sheet requirements before any commercial use.
Where to buy tetramethylplumbane in Europe?
Tetramethylplumbane is available through specialized chemical distributors like OYSI, which supplies industrial chemicals across Europe. Due to its extreme hazard classification and regulatory restrictions, procurement requires proper authorization and compliance documentation. Buyers must demonstrate legitimate use, appropriate safety measures, and regulatory compliance. Contact OYSI's technical team for availability, regulatory requirements, and safety consultation for this highly controlled substance.
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Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.