Oxiran-2-ylmethanol

C3H6O2

oxiran-2-ylmethanol

CAS556-52-5
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
Danger

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Identification

CAS Number
556-52-5
EC Number
209-128-3
UN Number
2810
Index Number
603-063-00-8
PubChem CID
11164

Physical-chemical properties

Molecular Formula
C3H6O2
Molar Mass
74.08 g/mol
IUPAC Name
oxiran-2-ylmethanol

Chemical Identifiers

InChI
InChI=1S/C3H6O2/c4-1-3-2-5-3/h3-4H,1-2H2
InChI Key
CTKINSOISVBQLD-UHFFFAOYSA-N

Overview

Oxiran-2-ylmethanol (CAS 556-52-5) is an epoxy alcohol compound characterized by its reactive oxirane ring and hydroxyl functional group. This glycidyl alcohol represents a significant chemical intermediate in industrial synthesis, combining the reactivity of an epoxide with the versatility of a primary alcohol. The compound's molecular structure, featuring both an oxirane ring and a hydroxyl group, makes it particularly valuable for creating cross-linked polymer networks and specialized chemical derivatives. With a molecular weight of 74.08 g/mol and the formula C3H6O2, oxiran-2-ylmethanol exhibits typical epoxide reactivity patterns while offering additional functionalization possibilities through its alcohol moiety. The substance requires careful handling protocols due to its classification as a Category 1B carcinogen, mutagen, and reproductive toxicant. The presence of GHS08 and GHS06 pictograms indicates serious health hazards, including potential cancer risk and acute toxicity. Its ADR Class 6.1 classification reflects the stringent transportation requirements necessary for safe logistics. Unlike more stable compounds such as N-methylaniline, oxiran-2-ylmethanol's dual reactive sites demand specialized storage conditions and enhanced safety measures. Primary industrial applications include epoxy resin modification, where it serves as a reactive diluent and cross-linking agent. The compound finds extensive use in adhesive formulations and coating systems requiring enhanced flexibility and chemical resistance. Additionally, it functions as a key intermediate in pharmaceutical synthesis and specialty polymer production. OYSI provides oxiran-2-ylmethanol with comprehensive safety documentation and regulatory compliance support for European industrial customers.

Safety & Classification

Danger
Classification:

Carc. 1B; Muta. 2; Repr. 1B; Acute Tox. 3 *; Acute Tox. 4 *; Acute Tox. 4 *; STOT SE 3; Skin Irri...

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H350

May cause cancer.

H341

Suspected of causing genetic defects.

H331

Toxic if inhaled.

H312

Harmful in contact with skin.

H302

Harmful if swallowed.

H335

May cause respiratory irritation.

H315

Causes skin irritation.

H319

Causes serious eye irritation.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Toxic

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Irritant

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2810
ADR Class6.1
Packing GroupIII
Tunnel CodeE
Proper Shipping Name2,3-Epoxypropan-1-ol
Marine PollutantNo

Frequently Asked Questions

What is oxiran-2-ylmethanol?

Oxiran-2-ylmethanol is an organic chemical compound with the molecular formula C3H6O2 and CAS number 556-52-5. It belongs to the epoxide family, featuring an oxirane ring attached to a methanol group. With a molecular weight of 74.08 g/mol, this compound is classified as highly hazardous due to its carcinogenic, mutagenic, and reproductive toxicity properties. It requires careful handling and is regulated under various safety frameworks.

What are the physicochemical properties of oxiran-2-ylmethanol?

Oxiran-2-ylmethanol is a colorless liquid at room temperature with the molecular formula C3H6O2. The compound has a molecular weight of 74.08 g/mol and contains both an epoxide ring and a hydroxyl group, making it polar and likely water-soluble. Its epoxide structure makes it highly reactive, particularly susceptible to ring-opening reactions. The presence of both ether and alcohol functionalities influences its physical and chemical behavior.

What is oxiran-2-ylmethanol used for?

Oxiran-2-ylmethanol serves as an important chemical intermediate in organic synthesis and industrial processes. Its epoxide functionality makes it valuable for producing polymers, resins, and various chemical derivatives through ring-opening reactions. It may be used in the manufacture of specialty chemicals, pharmaceuticals, and materials requiring reactive intermediates. However, its high toxicity classification limits its applications to controlled industrial environments with appropriate safety measures.

How to handle oxiran-2-ylmethanol safely?

Oxiran-2-ylmethanol requires extreme caution during handling due to its Danger signal word and multiple hazard classifications. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and respiratory protection. Work should be conducted in well-ventilated areas or under fume hoods. Avoid skin and eye contact, inhalation, and ingestion. Emergency procedures must be established, and only trained personnel should handle this substance following strict safety protocols.

How to store oxiran-2-ylmethanol correctly?

Oxiran-2-ylmethanol must be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Due to its reactive epoxide nature, avoid contact with acids, bases, and nucleophiles that could trigger ring-opening reactions. Storage areas should be equipped with appropriate containment measures and restricted to authorized personnel only. Regular container inspection is essential due to the compound's hazardous classification.

What to do in case of contact with oxiran-2-ylmethanol?

Oxiran-2-ylmethanol exposure requires immediate emergency response due to its high toxicity. For skin contact, remove contaminated clothing and rinse affected area with plenty of water for at least 15 minutes. In case of eye contact, flush immediately with water and seek medical attention. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical attention. Always consult safety data sheets for complete emergency procedures.

How to dispose of oxiran-2-ylmethanol appropriately?

Oxiran-2-ylmethanol disposal must comply with local and European waste regulations due to its hazardous classification. The substance requires treatment as hazardous waste and cannot be disposed of through normal channels. Contact licensed waste disposal companies experienced in handling toxic chemicals. Incineration at authorized facilities may be appropriate. Empty containers should also be treated as hazardous waste. Consult local environmental authorities for specific disposal requirements.

How to transport oxiran-2-ylmethanol?

Oxiran-2-ylmethanol is classified under ADR Class 6.1 (toxic substances), Packing Group III for transportation purposes. This classification requires specific packaging, labeling, and documentation according to dangerous goods regulations. Transport vehicles must display appropriate hazard placards, and drivers require ADR certification. Proper shipping papers and emergency response information must accompany shipments. Only authorized carriers experienced in hazardous materials should handle transportation.

Is oxiran-2-ylmethanol subject to specific regulations?

Oxiran-2-ylmethanol is subject to extensive European chemical regulations including REACH registration and CLP classification requirements. Its multiple hazard classes (Carc. 1B, Muta. 2, Repr. 1B) trigger strict regulatory controls and workplace exposure limits. Although not currently listed as SVHC, its hazard profile requires compliance with occupational safety regulations and potentially authorization procedures. Users must maintain safety data sheets and implement appropriate risk management measures.

Where to buy oxiran-2-ylmethanol in Europe?

Oxiran-2-ylmethanol is available through OYSI, a specialized European distributor of technical chemicals. As a professional chemical supplier, OYSI provides this regulated substance to qualified industrial customers with appropriate safety credentials and handling capabilities. Due to the compound's hazardous classification, purchases typically require verification of proper storage facilities, trained personnel, and compliance with relevant safety regulations. Contact OYSI directly for availability and technical specifications.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.