Oxiran-2-ylmethanol
C3H6O2
oxiran-2-ylmethanol
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Identification
- CAS Number
- 556-52-5
- EC Number
- 209-128-3
- UN Number
- 2810
- Index Number
- 603-063-00-8
- PubChem CID
- 11164
Physical-chemical properties
- Molecular Formula
- C3H6O2
- Molar Mass
- 74.08 g/mol
- IUPAC Name
- oxiran-2-ylmethanol
Chemical Identifiers
- InChI
- InChI=1S/C3H6O2/c4-1-3-2-5-3/h3-4H,1-2H2
- InChI Key
- CTKINSOISVBQLD-UHFFFAOYSA-N
Overview
Oxiran-2-ylmethanol (CAS 556-52-5) is an epoxide compound with highly reactive three-membered ring structure and significant industrial applications. This glycidyl alcohol derivative, also known by its IUPAC designation oxiran-2-ylmethanol, represents a critical intermediate in epoxy chemistry and polymer synthesis. With the molecular formula C3H6O2 and molecular weight of 74.08 g/mol, this compound features both an epoxide ring and a hydroxyl group, making it exceptionally versatile for chemical modifications and cross-linking reactions. The substance exhibits significant hazard characteristics, classified under multiple danger categories including carcinogenicity (1B), mutagenicity (2), and reproductive toxicity (1B), requiring stringent handling protocols and appropriate safety equipment. Its acute toxicity properties and skin irritation potential necessitate comprehensive risk management procedures in industrial applications. The compound falls under ADR transport class 6.1, reflecting its toxic nature during shipping and storage. Primary industrial applications include epoxy resin production, where oxiran-2-ylmethanol serves as a reactive diluent and cross-linking agent. The pharmaceutical and agrochemical industries utilize this compound as a building block for synthesizing complex molecules. Additionally, it functions as an intermediate in specialty polymer manufacturing, particularly in applications requiring enhanced adhesion properties. Unlike related compounds such as chloromethylbenzene or N-methylaniline, which serve different synthetic pathways, oxiran-2-ylmethanol's dual functionality as both epoxide and alcohol makes it particularly valuable for creating branched polymer structures and surface modification applications. OYSI provides technical-grade oxiran-2-ylmethanol with comprehensive documentation and regulatory compliance support for European industrial customers.
Safety & Classification
Carc. 1B; Muta. 2; Repr. 1B; Acute Tox. 3 *; Acute Tox. 4 *; Acute Tox. 4 *; STOT SE 3; Skin Irri...
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Inhalation
Measures if vapours or dust are inhaled
Skin Contact
Measures if substance contacts the skin
Eye Contact
Measures if substance gets into the eyes
First Aid Actions
- +P305IF IN EYES:
- +P351Rinse cautiously with water for several minutes.
- +P338Remove contact lenses, if present and easy to do. Continue rinsing.
- +P313Get medical advice/attention.
Related hazard statements:
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 2810 |
| ADR Class | 6.1 |
| Packing Group | III |
| Tunnel Code | E |
| Proper Shipping Name | 2,3-Epoxypropan-1-ol |
| Marine Pollutant | No |
Frequently Asked Questions
What is oxiran-2-ylmethanol?
Oxiran-2-ylmethanol is a chemical compound with the molecular formula C3H6O2 and CAS number 556-52-5. This substance has a molecular weight of 74.08 g/mol and belongs to the epoxy alcohol family. It is classified as a highly hazardous substance with multiple health risks including carcinogenic, mutagenic, and reproductive toxicity properties. The compound requires careful handling due to its acute toxicity and skin irritation potential, warranting strict safety protocols in industrial applications.
What are the physicochemical properties of oxiran-2-ylmethanol?
Oxiran-2-ylmethanol is a liquid organic compound at room temperature with characteristic properties typical of epoxy alcohols. The substance contains both an epoxide ring and a hydroxyl group, making it reactive and polar. Due to its hydroxyl group, it exhibits good solubility in polar solvents and water. The compound's molecular structure with the epoxide functionality makes it highly reactive, particularly in ring-opening reactions, which contributes to its industrial utility but also to its hazardous nature.
What is oxiran-2-ylmethanol used for?
Oxiran-2-ylmethanol serves as an important intermediate in organic synthesis and industrial chemical processes. The compound is primarily used in the production of various chemical derivatives through its reactive epoxide and alcohol functional groups. It finds applications in polymer chemistry, pharmaceutical synthesis, and as a building block for specialty chemicals. Due to its high toxicity profile, its use is restricted to professional industrial settings with appropriate safety measures and regulatory compliance.
How to handle oxiran-2-ylmethanol safely?
Oxiran-2-ylmethanol requires extreme caution during handling due to its classification as Carc. 1B, Muta. 2, and Repr. 1B. Essential personal protective equipment includes chemical-resistant gloves, protective clothing, eye protection, and respiratory protection. Work must be conducted in well-ventilated areas or under fume hoods. Avoid skin contact, inhalation, and ingestion. All personnel must be trained on the specific hazards and emergency procedures before handling this dangerous substance.
How to store oxiran-2-ylmethanol correctly?
Oxiran-2-ylmethanol must be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Due to its reactive epoxide group, avoid contact with acids, bases, and nucleophilic substances that could cause ring-opening reactions. Storage areas should be equipped with appropriate containment measures and emergency equipment. Access must be restricted to authorized personnel only, with proper labeling indicating the multiple hazard classifications including carcinogenic and reproductive toxicity risks.
What to do in case of contact with oxiran-2-ylmethanol?
Oxiran-2-ylmethanol exposure requires immediate emergency response due to its acute toxicity. For skin contact, immediately remove contaminated clothing and rinse with copious amounts of water for at least 15 minutes. In case of eye contact, flush thoroughly with water and seek immediate medical attention. If inhaled, move the person to fresh air and provide respiratory support if needed. For ingestion, do not induce vomiting and seek immediate medical attention. Always consult emergency services and provide the safety data sheet to medical personnel.
How to dispose of oxiran-2-ylmethanol appropriately?
Oxiran-2-ylmethanol disposal must comply with hazardous waste regulations due to its classification as a dangerous substance. The compound cannot be disposed of through normal waste streams and requires specialized hazardous waste treatment facilities. Container disposal must follow local and European waste regulations, with proper classification under hazardous waste codes. Waste generators must use licensed waste disposal companies with appropriate permits for handling carcinogenic and toxic substances. All disposal activities must be documented for regulatory compliance.
How to transport oxiran-2-ylmethanol?
Oxiran-2-ylmethanol is classified under ADR Class 6.1 (Toxic substances), Packing Group III for transportation purposes. The substance requires proper packaging in UN-approved containers with appropriate hazard labels and documentation. Transport vehicles must comply with ADR regulations for toxic substances, including proper placarding and emergency equipment. Drivers must hold appropriate dangerous goods certificates, and transport documentation must include emergency response information. Special precautions are required due to the substance's multiple health hazards.
Is oxiran-2-ylmethanol subject to specific regulations?
Oxiran-2-ylmethanol is subject to extensive European chemical regulations including REACH registration requirements and CLP classification obligations. The substance's classification as Carc. 1B, Muta. 2, and Repr. 1B triggers strict regulatory controls under various EU directives. Although not currently listed as an SVHC, its hazard profile requires compliance with occupational exposure limits, risk assessment procedures, and safety data sheet provisions. Industrial users must implement appropriate risk management measures and worker protection programs under applicable health and safety legislation.
Where to buy oxiran-2-ylmethanol in Europe?
Oxiran-2-ylmethanol is available through specialized chemical distributors in Europe, including OYSI, which serves as a reliable supplier of technical chemicals across European markets. Due to the substance's hazardous classification, procurement is restricted to qualified industrial users with appropriate handling capabilities and regulatory compliance. Suppliers must provide proper documentation including safety data sheets, certificates of analysis, and transport classification information. Professional consultation is recommended to ensure proper handling, storage, and regulatory compliance throughout the supply chain.
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Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.