Prop-2-enamide

C3H5NO

prop-2-enamide

CAS79-06-1
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
Danger

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Identification

CAS Number
79-06-1
EC Number
201-173-7
UN Number
2074
Index Number
616-003-00-0
PubChem CID
6579

Physical-chemical properties

Molecular Formula
C3H5NO
Molar Mass
71.08 g/mol
IUPAC Name
prop-2-enamide

Chemical Identifiers

InChI
InChI=1S/C3H5NO/c1-2-3(4)5/h2H,1H2,(H2,4,5)
InChI Key
HRPVXLWXLXDGHG-UHFFFAOYSA-N

Overview

Prop-2-enamide (CAS 79-06-1) is an unsaturated amide compound with significant industrial applications despite serious health hazards requiring strict handling protocols. This vinyl amide represents a critical building block in polymer chemistry and industrial synthesis, characterized by its reactive double bond structure that enables polymerization reactions. With the molecular formula C3H5NO and a molecular weight of 71.08 g/mol, prop-2-enamide exhibits unique chemical properties that make it valuable in specialized manufacturing processes, though its use is heavily regulated due to substantial health concerns. The compound presents severe safety considerations, classified as a Category 1B carcinogen and mutagen, with additional reproductive toxicity properties. Its hazard profile includes acute toxicity through multiple exposure routes and specific target organ toxicity following repeated exposure. The GHS08 and GHS06 pictograms underscore the serious health risks, requiring comprehensive risk management measures including specialized ventilation, personal protective equipment, and rigorous exposure monitoring protocols. Primary industrial applications include polymerization processes for specialty polymers, chemical synthesis intermediates, and research applications in materials science. The compound's reactivity profile makes it particularly suitable for creating crosslinked polymer networks and as a comonomer in advanced material formulations. Unlike related aromatic compounds such as N-methylaniline, prop-2-enamide's vinyl functionality provides distinct polymerization characteristics essential for specific industrial processes. Transportation regulations classify this material under ADR Class 6.1, reflecting its toxic properties and requiring specialized logistics handling. Manufacturing facilities utilizing prop-2-enamide must implement stringent safety protocols and ensure compliance with occupational exposure limits. OYSI provides prop-2-enamide to qualified industrial customers with comprehensive safety documentation and regulatory compliance support for European markets.

Safety & Classification

Danger
Classification:

Carc. 1B; Muta. 1B; Repr. 2; Acute Tox. 4 *; Acute Tox. 4 *; Acute Tox. 3 *; STOT RE 1; Skin Irri...

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H350

May cause cancer.

H340

May cause genetic defects.

H332

Harmful if inhaled.

H312

Harmful in contact with skin.

H301

Toxic if swallowed.

H372

Causes damage to organs through prolonged or repeated exposure.

H315

Causes skin irritation.

H319

Causes serious eye irritation.

H317

May cause an allergic skin reaction.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Harmful

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Irritant

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Toxic

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2074
ADR Class6.1
Packing GroupIII
Tunnel CodeE
Proper Shipping NameAcrylamid, fest
Marine PollutantNo

Frequently Asked Questions

What is prop-2-enamide?

Prop-2-enamide is an organic chemical compound with the molecular formula C3H5NO and CAS number 79-06-1. It has a molecular weight of 71.08 g/mol and belongs to the amide family of compounds. This substance is classified as highly hazardous due to its carcinogenic, mutagenic, and toxic properties. It requires careful handling and is subject to strict regulatory controls due to its significant health risks.

What are the physicochemical properties of prop-2-enamide?

Prop-2-enamide is a solid crystalline compound at room temperature, typically appearing as white or colorless crystals. It is highly soluble in water and polar solvents due to its amide functional group. The compound has a molecular weight of 71.08 g/mol and contains both carbon-carbon double bond and amide functionalities, making it reactive under certain conditions. Its physical state and solubility characteristics facilitate its industrial applications.

What is prop-2-enamide used for?

Prop-2-enamide is primarily used as a monomer in the production of polyacrylamide polymers, which find applications in water treatment, paper manufacturing, and enhanced oil recovery. It serves as a chemical intermediate in the synthesis of various industrial compounds and is used in the production of adhesives, coatings, and textile treatments. The compound is also utilized in research and development applications within the chemical industry.

How to handle prop-2-enamide safely?

Prop-2-enamide requires extreme caution during handling due to its carcinogenic and mutagenic properties. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and respiratory protection in well-ventilated areas. Work should be conducted in fume hoods or controlled environments to prevent inhalation or skin contact. All handling procedures must comply with occupational safety guidelines, and workers should receive specialized training before working with this hazardous substance.

How to store prop-2-enamide correctly?

Prop-2-enamide must be stored in cool, dry, well-ventilated areas away from heat sources and direct sunlight. The substance should be kept in tightly sealed, labeled containers made of compatible materials. Storage areas must be secured and accessible only to trained personnel due to the compound's hazardous nature. Incompatible materials should be stored separately, and emergency response equipment should be readily available in storage areas.

What to do in case of contact with prop-2-enamide?

Immediate action is required for any contact with prop-2-enamide. For skin contact, remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. In case of eye contact, flush immediately with clean water for 15-20 minutes. If inhaled, move the person to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical attention, providing the safety data sheet to medical personnel.

How to dispose of prop-2-enamide appropriately?

Prop-2-enamide disposal must comply with local and international hazardous waste regulations due to its toxic and carcinogenic properties. The substance cannot be disposed of in regular waste streams and requires specialized hazardous waste treatment facilities. Disposal should be arranged through licensed waste management companies capable of handling carcinogenic materials. All disposal activities must be documented and tracked according to regulatory requirements.

How to transport prop-2-enamide?

Prop-2-enamide is classified under ADR Class 6.1 (toxic substances), Packing Group III for transportation purposes. The substance must be packaged in approved containers with appropriate hazard labels and documentation. Transportation requires compliance with dangerous goods regulations, including proper vehicle marking, driver certification, and emergency response information. All transport activities must follow international dangerous goods transport protocols.

Is prop-2-enamide subject to specific regulations?

Prop-2-enamide is subject to extensive regulatory oversight under REACH and CLP regulations in Europe due to its hazardous classification. The substance is classified as carcinogenic (1B), mutagenic (1B), and toxic to reproduction (2), requiring strict compliance with occupational exposure limits and safety measures. Special authorization may be required for certain uses, and comprehensive risk assessments must be conducted before handling or processing this compound.

Where to buy prop-2-enamide in Europe?

Prop-2-enamide is available through OYSI, a specialized European distributor of technical chemicals with expertise in hazardous substances. As a professional chemical distributor, OYSI provides compliant packaging, proper documentation, and regulatory support for this controlled substance. Purchase requires verification of legitimate industrial use and compliance with safety regulations. Contact OYSI directly for availability, technical specifications, and regulatory guidance for your specific application requirements.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.