Prop-2-enamide

C3H5NO

prop-2-enamide

CAS79-06-1
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
Danger

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Identification

CAS Number
79-06-1
EC Number
201-173-7
UN Number
2074
Index Number
616-003-00-0
PubChem CID
6579

Physical-chemical properties

Molecular Formula
C3H5NO
Molar Mass
71.08 g/mol
IUPAC Name
prop-2-enamide

Chemical Identifiers

InChI
InChI=1S/C3H5NO/c1-2-3(4)5/h2H,1H2,(H2,4,5)
InChI Key
HRPVXLWXLXDGHG-UHFFFAOYSA-N

Overview

Prop-2-enamide (CAS 79-06-1) is an unsaturated amide compound with significant industrial applications but requiring strict safety protocols due to its hazardous properties. This vinyl amide derivative, with molecular formula C3H5NO and molecular weight 71.08 g/mol, represents an important building block in polymer chemistry and various industrial processes. The compound features a characteristic double bond adjacent to the amide functional group, making it highly reactive and valuable for polymerization reactions. However, prop-2-enamide carries severe health warnings, classified as carcinogenic (Category 1B), mutagenic (Category 1B), and potentially harmful to reproduction (Category 2), requiring extreme caution during handling and storage. The substance presents multiple hazard classifications including acute toxicity and specific target organ toxicity after repeated exposure (STOT RE 1), reflected in its ADR Class 6.1 designation and GHS pictograms GHS08 and GHS06. These safety concerns necessitate comprehensive risk management protocols and specialized handling equipment in industrial settings. Primary industrial applications include polymer production, where prop-2-enamide serves as a monomer for creating specialized polyacrylamide materials used in water treatment and enhanced oil recovery. It also functions as an intermediate in the synthesis of various chemical compounds and finds use in research applications for developing new materials with specific properties. Unlike less hazardous compounds such as N-methylaniline, prop-2-enamide requires significantly more stringent safety measures throughout its supply chain. OYSI maintains reliable supply capabilities for prop-2-enamide, supported by comprehensive safety documentation and regulatory compliance expertise to ensure proper handling throughout the European market.

Safety & Classification

Danger
Classification:

Carc. 1B; Muta. 1B; Repr. 2; Acute Tox. 4 *; Acute Tox. 4 *; Acute Tox. 3 *; STOT RE 1; Skin Irri...

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H350

May cause cancer.

H340

May cause genetic defects.

H332

Harmful if inhaled.

H312

Harmful in contact with skin.

H301

Toxic if swallowed.

H372

Causes damage to organs through prolonged or repeated exposure.

H315

Causes skin irritation.

H319

Causes serious eye irritation.

H317

May cause an allergic skin reaction.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Harmful

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Irritant

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Toxic

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2074
ADR Class6.1
Packing GroupIII
Tunnel CodeE
Proper Shipping NameAcrylamid, fest
Marine PollutantNo

Frequently Asked Questions

What is prop-2-enamide?

Prop-2-enamide is an organic chemical compound with the molecular formula C3H5NO and CAS number 79-06-1. It has a molecular weight of 71.08 g/mol and belongs to the amide family of compounds. This substance is classified as highly hazardous due to its carcinogenic, mutagenic, and reproductive toxicity properties, requiring strict handling protocols and safety measures in industrial applications.

What are the physicochemical properties of prop-2-enamide?

Prop-2-enamide is a small organic molecule with the formula C3H5NO and a molecular mass of 71.08 g/mol. As an amide compound, it typically appears as a white crystalline solid at room temperature. The substance is highly water-soluble due to its polar amide functional group, which allows for hydrogen bonding with water molecules, making it readily miscible in aqueous solutions.

What is prop-2-enamide used for?

Prop-2-enamide is primarily used as a chemical intermediate in polymer synthesis and as a monomer in the production of various industrial polymers. It serves as a building block for creating specialized materials with specific properties. Due to its high toxicity profile including carcinogenic and mutagenic properties, its applications are strictly regulated and limited to controlled industrial processes where proper safety measures can be implemented.

How to handle prop-2-enamide safely?

Prop-2-enamide requires extreme safety precautions due to its classification as Carc. 1B, Muta. 1B, and acute toxicity. Personal protective equipment must include chemical-resistant gloves, safety goggles, and respiratory protection. Work should be conducted in well-ventilated areas or fume hoods. Avoid skin and eye contact, inhalation, and ingestion. Only trained personnel should handle this substance following established safety protocols and risk assessments.

How to store prop-2-enamide correctly?

Prop-2-enamide must be stored in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Containers should be tightly sealed and properly labeled with appropriate hazard warnings. Storage areas must be restricted to authorized personnel only due to the substance's carcinogenic and mutagenic properties. Regular inventory checks and proper segregation from other chemicals are essential for safe storage management.

What to do in case of contact with prop-2-enamide?

Immediate action is required for any contact with prop-2-enamide due to its high toxicity. For skin contact, remove contaminated clothing and wash thoroughly with soap and water. In case of eye contact, flush immediately with water for at least 15 minutes. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical attention. Always contact emergency services for serious exposures.

How to dispose of prop-2-enamide appropriately?

Prop-2-enamide disposal must comply with local and international hazardous waste regulations due to its toxic properties. The substance cannot be disposed of through regular waste streams and requires specialized hazardous waste treatment. Contact licensed waste disposal companies experienced in handling carcinogenic materials. All disposal activities must be documented and follow proper chain of custody procedures as required by environmental regulations.

How to transport prop-2-enamide?

Prop-2-enamide is classified under ADR Class 6.1 (Toxic substances), Packing Group III for transportation purposes. Packages must be properly labeled with appropriate hazard markings and documentation. Transportation requires compliance with dangerous goods regulations, including proper packaging, labeling, and carrier certification. Only authorized transport companies experienced in handling toxic chemicals should be used for shipment of this substance.

Is prop-2-enamide subject to specific regulations?

Prop-2-enamide is subject to strict regulatory oversight under REACH and CLP regulations due to its hazardous classification. The substance requires safety data sheets, risk assessments, and proper hazard communication. Its carcinogenic and mutagenic properties may trigger additional restrictions on use and handling. Companies must comply with occupational exposure limits and implement appropriate risk management measures as mandated by chemical safety regulations.

Where to buy prop-2-enamide in Europe?

Prop-2-enamide is available through specialized chemical distributors in Europe, including OYSI, which serves as a reliable European supplier of technical chemicals. Due to its hazardous nature, purchases are typically restricted to qualified industrial users with proper safety protocols and regulatory compliance. Suppliers must provide comprehensive safety documentation and ensure proper handling and transportation procedures are followed throughout the supply chain.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.