N,N-diethylethanamine

C6H15N

CAS121-44-8
GHS02 Gefahrensymbol: Entzündbar – Flamme
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
GHS05 Gefahrensymbol: Ätzend – Ätzwirkung
Danger

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Identification

CAS Number
121-44-8
EC Number
204-469-4
UN Number
1296
Index Number
612-004-00-5
PubChem CID
8471

Physical-chemical properties

Molecular Formula
C6H15N
Molar Mass
101.19 g/mol
IUPAC Name
N,N-diethylethanamine

Chemical Identifiers

InChI
InChI=1S/C6H15N/c1-4-7(5-2)6-3/h4-6H2,1-3H3
InChI Key
ZMANZCXQSJIPKH-UHFFFAOYSA-N

Overview

N,N-diethylethanamine (CAS 121-44-8) is a tertiary aliphatic amine with strong basic properties and high chemical reactivity. This colorless liquid compound, also known as triethylamine, represents one of the most widely used tertiary amines in industrial chemistry, serving as both a chemical intermediate and process catalyst across numerous applications. With the molecular formula C6H15N and a molecular weight of 101.19 g/mol, this volatile organic compound exhibits typical tertiary amine characteristics including a distinctive fishy odor and strong alkaline behavior. The substance's chemical structure, featuring three ethyl groups attached to a central nitrogen atom, provides excellent nucleophilic properties that make it valuable for various synthetic processes. Unlike simpler amines such as 2-methylaziridine, triethylamine's tertiary structure offers enhanced stability and selectivity in chemical reactions. Safety considerations are paramount when handling N,N-diethylethanamine, as it carries significant hazard classifications including flammable liquid category 2, acute toxicity category 3, skin corrosion category 1A, and serious eye damage category 1. The substance requires careful handling protocols due to its corrosive nature and potential health impacts through inhalation, skin contact, or ingestion. Proper ventilation, personal protective equipment, and emergency response procedures are essential for safe operations. Industrial applications include its use as a catalyst in polyurethane foam production, as a curing agent for epoxy resins, and as an intermediate in pharmaceutical synthesis. The compound also serves as a base in organic synthesis reactions and finds application in the production of quaternary ammonium compounds. Similar to N',N'-diethylpropane-1,3-diamine, it demonstrates excellent performance in specialized chemical processes requiring controlled basicity. OYSI maintains reliable supply chains for N,N-diethylethanamine to support diverse European industrial requirements with consistent quality and technical support.

Safety & Classification

Danger
Classification:

Flam. Liq. 2; Acute Tox. 3; Acute Tox. 3; Acute Tox. 3; Skin Corr. 1A; Eye Dam. 1

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H225

Highly flammable liquid and vapour.

H331

Toxic if inhaled.

H311

Toxic in contact with skin.

H301

Toxic if swallowed.

H314

Causes severe skin burns and eye damage.

H318

Causes serious eye damage.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Toxic

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Toxic

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Harmful

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Toxic

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number1296
ADR Class3
Packing GroupII
Tunnel CodeD/E
Proper Shipping NameTriethylamin
Marine PollutantNo

Frequently Asked Questions

What is N,N-diethylethanamine?

N,N-diethylethanamine is a tertiary amine compound with the chemical formula C6H15N and CAS number 121-44-8. This organic chemical has a molecular weight of 101.19 g/mol and belongs to the family of aliphatic amines. It is classified as a hazardous substance with multiple danger classifications including flammable liquid, acute toxicity, skin corrosion, and eye damage properties, requiring careful handling in industrial applications.

What are the physicochemical properties of N,N-diethylethanamine?

N,N-diethylethanamine is typically a colorless to pale yellow liquid at room temperature with a characteristic amine odor. As a tertiary amine, it exhibits basic properties and is miscible with water and most organic solvents. The compound has flammable properties (Flam. Liq. 2 classification) and demonstrates corrosive characteristics toward skin and eyes, making it highly reactive with acids and other electrophilic compounds.

What is N,N-diethylethanamine used for?

N,N-diethylethanamine serves primarily as a chemical intermediate and catalyst in various industrial processes. It is commonly used in organic synthesis reactions, particularly as a base catalyst in pharmaceutical manufacturing, polymer production, and fine chemical synthesis. The compound also finds applications in the production of surfactants, corrosion inhibitors, and as a reagent in analytical chemistry procedures requiring a tertiary amine catalyst.

How to handle N,N-diethylethanamine safely?

N,N-diethylethanamine requires strict safety measures due to its corrosive and toxic properties. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, face shields, and acid-resistant clothing. Work must be conducted in well-ventilated areas or under fume hoods to prevent inhalation. Avoid contact with skin, eyes, and clothing, and ensure emergency shower and eyewash stations are readily accessible during handling operations.

How to store N,N-diethylethanamine correctly?

N,N-diethylethanamine must be stored in tightly sealed containers in cool, dry, well-ventilated areas away from heat sources and ignition points. Keep the substance separated from acids, oxidizing agents, and incompatible materials to prevent dangerous reactions. Storage areas should be equipped with appropriate fire suppression systems and spill containment measures. Containers should be properly labeled and stored according to flammable liquid storage regulations.

What to do in case of contact with N,N-diethylethanamine?

Immediate action is required for any contact with N,N-diethylethanamine due to its corrosive nature. For skin contact, remove contaminated clothing and flush affected areas with copious amounts of water for at least 15 minutes. In case of eye contact, rinse immediately with water for at least 15 minutes and seek medical attention. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical care.

How to dispose of N,N-diethylethanamine properly?

N,N-diethylethanamine disposal must comply with local and European waste regulations due to its hazardous classification. The substance cannot be disposed of in regular waste streams and requires treatment as hazardous chemical waste. Contact licensed hazardous waste disposal companies for proper collection and treatment. Small quantities may be neutralized under controlled conditions by qualified personnel, but large volumes require professional hazardous waste management services following EU waste directives.

How to transport N,N-diethylethanamine?

N,N-diethylethanamine is classified as ADR Class 3 (flammable liquids) Packing Group II, requiring compliance with dangerous goods transportation regulations. Containers must be UN-approved and properly labeled with appropriate hazard placards and shipping documentation. Transportation vehicles need ADR certification, and drivers must hold valid dangerous goods licenses. The substance requires appropriate packaging, marking, and documentation according to European ADR regulations for road transport.

Is N,N-diethylethanamine subject to specific regulations?

N,N-diethylethanamine is subject to various European chemical regulations including REACH registration requirements and CLP classification standards. The substance must comply with workplace exposure limits and industrial emissions regulations. While not currently listed as an SVHC (Substance of Very High Concern), its hazardous properties require compliance with occupational health and safety directives, environmental protection measures, and proper chemical safety assessments under EU legislation.

Where to buy N,N-diethylethanamine in Europe?

N,N-diethylethanamine is available through OYSI, a specialized European distributor of technical chemicals serving industrial customers across the continent. OYSI provides this substance with proper documentation, safety data sheets, and regulatory compliance support. As a professional chemical distributor, OYSI ensures quality standards and reliable supply chains for industrial applications requiring N,N-diethylethanamine, supporting customers with technical expertise and regulatory guidance throughout Europe.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.